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The map label for this gene is amaA [H]

Identifier: 52142335

GI number: 52142335

Start: 3036160

End: 3037365

Strand: Reverse

Name: amaA [H]

Synonym: BCZK2908

Alternate gene names: 52142335

Gene position: 3037365-3036160 (Counterclockwise)

Preceding gene: 52142333

Following gene: 52142337

Centisome position: 57.3

GC content: 42.54

Gene sequence:

>1206_bases
ATGGGAGCGACAGGAGTAGCGTCACAAAGAAAAACAATTGAAGAGAGTATCGAAAGAAATAAGGAAAAGTACATAGAAAC
AAGTCATGATATTCATGCGAATCCAGAGATTGGTAATCAAGAGTTTTACGCATCTAGAACGTTAAGTTTATTGCTAGGTA
GTGCCGGATTTCAGTTGCAGCACAATATAGCTGGACACGAAACAGGATTTATCGCGCGAAAAAGTTCAGGAAAACAAGGA
CCAGCAATCGCATTTTTAGCTGAGTATGACGCTTTACCAGGACTCGGTCATGCGTGTGGTCACAATTTAATCGGCACCAT
TAGCGTTGCAGCAGCGATTGCATTATCAGAAACGCTTGAAGAAATCGGCGGGGAAGTTGTTGTATTTGGAACACCAGCAG
AAGAAGGCGGGCCAAACGGTAGCGCAAAATCGAGTTATGTAAAGGCAGGTTTATTTAAAAATATTGATGCAGCACTTATG
ATTCATCCGAGTGGAAAAACAGCGACGACGAGCCCTTCACTAGCAGTCGATCCACTTGATTTTCATTTTTACGGAAAAAC
AGCTCATGCTGCAGCTTCACCTGAAGAAGGAATTAACGCATTAGATGCGGTGATTCAGCTGTACAACAGTATTAACGCAC
TTCGACAACAACTTCCGTCAGATGTGAGAATTCATGGCGTGATTACAGAAGGCGGAAAAGCACCTAACATTATTCCTGAC
TACGCCGCGGCAAGGTTCTTCATCCGTGCAGCAACGCGACAAAGATGTGCAGAAGTAACAGAAAAAGTAAAAAATATCGC
ACAGGGAGCAGCGTTAGCAACAGGAACAAAAGTAAAAATCCATCAATTCCAAAATGAAATCGATGAACTGCTCGTAACAA
AAACATATAACGACGTCGTAGCTGAAGAACTAGAATTACTCGGGGAAGACGTAAATCGTAAAGAAAGATTTGGTATTGGT
TCAACCGATGCAGGAAACGTTAGCCAAGTTGTACCGACAATCCATCCGTACATTAAAATCGGGCCAGATGATTTAATTGC
ACATACGAATGAATTTAGAGAAGCAGCGCGTTCAGAATTAGGAGACAAAGCTCTAATTACATCCGCAAAAGCACTAGCAA
ATACCGCGTATCGATTAATTACGGAAGAAGGGTTGTTAGAGAAGGTGAAGGAAGAGTTTAGAGAGGCGCAGAGGAATCAG
GGGTAG

Upstream 100 bases:

>100_bases
GAAAGATAAGAAAGAAGCTCATTTTGACTGTATATACAGAAGCCTCTTTCTATCTTTTAGAAAGAGGCTTTTTTACGTGA
AAATAAAAGGAGGAAGAAAA

Downstream 100 bases:

>100_bases
ATGATTAAAGGGAGTGGATGATCCACTCCTTTTTCTTTTTTGGAAAGCTGGTGCCTATCACTTTATTAGAACGACAATTT
CTCCTCAAACTCACTCTTTA

Product: N-acyl-L-amino acid amidohydrolase

Products: carboxylate; L-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MGATGVASQRKTIEESIERNKEKYIETSHDIHANPEIGNQEFYASRTLSLLLGSAGFQLQHNIAGHETGFIARKSSGKQG
PAIAFLAEYDALPGLGHACGHNLIGTISVAAAIALSETLEEIGGEVVVFGTPAEEGGPNGSAKSSYVKAGLFKNIDAALM
IHPSGKTATTSPSLAVDPLDFHFYGKTAHAAASPEEGINALDAVIQLYNSINALRQQLPSDVRIHGVITEGGKAPNIIPD
YAAARFFIRAATRQRCAEVTEKVKNIAQGAALATGTKVKIHQFQNEIDELLVTKTYNDVVAEELELLGEDVNRKERFGIG
STDAGNVSQVVPTIHPYIKIGPDDLIAHTNEFREAARSELGDKALITSAKALANTAYRLITEEGLLEKVKEEFREAQRNQ
G

Sequences:

>Translated_401_residues
MGATGVASQRKTIEESIERNKEKYIETSHDIHANPEIGNQEFYASRTLSLLLGSAGFQLQHNIAGHETGFIARKSSGKQG
PAIAFLAEYDALPGLGHACGHNLIGTISVAAAIALSETLEEIGGEVVVFGTPAEEGGPNGSAKSSYVKAGLFKNIDAALM
IHPSGKTATTSPSLAVDPLDFHFYGKTAHAAASPEEGINALDAVIQLYNSINALRQQLPSDVRIHGVITEGGKAPNIIPD
YAAARFFIRAATRQRCAEVTEKVKNIAQGAALATGTKVKIHQFQNEIDELLVTKTYNDVVAEELELLGEDVNRKERFGIG
STDAGNVSQVVPTIHPYIKIGPDDLIAHTNEFREAARSELGDKALITSAKALANTAYRLITEEGLLEKVKEEFREAQRNQ
G
>Mature_400_residues
GATGVASQRKTIEESIERNKEKYIETSHDIHANPEIGNQEFYASRTLSLLLGSAGFQLQHNIAGHETGFIARKSSGKQGP
AIAFLAEYDALPGLGHACGHNLIGTISVAAAIALSETLEEIGGEVVVFGTPAEEGGPNGSAKSSYVKAGLFKNIDAALMI
HPSGKTATTSPSLAVDPLDFHFYGKTAHAAASPEEGINALDAVIQLYNSINALRQQLPSDVRIHGVITEGGKAPNIIPDY
AAARFFIRAATRQRCAEVTEKVKNIAQGAALATGTKVKIHQFQNEIDELLVTKTYNDVVAEELELLGEDVNRKERFGIGS
TDAGNVSQVVPTIHPYIKIGPDDLIAHTNEFREAARSELGDKALITSAKALANTAYRLITEEGLLEKVKEEFREAQRNQG

Specific function: Required but not essential for aminobenzoyl-glutamate utilization. May participate in hydrolysis of aminobenzoyl- glutamate to aminobenzoate, either alone or in combination with AbgA [H]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI58082085, Length=404, Percent_Identity=36.3861386138614, Blast_Score=228, Evalue=5e-60,
Organism=Escherichia coli, GI1787598, Length=319, Percent_Identity=35.423197492163, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI87081880, Length=239, Percent_Identity=26.7782426778243, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017145
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.5.1.14

Molecular weight: Translated: 42963; Mature: 42832

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGATGVASQRKTIEESIERNKEKYIETSHDIHANPEIGNQEFYASRTLSLLLGSAGFQLQ
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
HNIAGHETGFIARKSSGKQGPAIAFLAEYDALPGLGHACGHNLIGTISVAAAIALSETLE
ECCCCCCCCEEEECCCCCCCCEEEEEEHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
EIGGEVVVFGTPAEEGGPNGSAKSSYVKAGLFKNIDAALMIHPSGKTATTSPSLAVDPLD
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCE
FHFYGKTAHAAASPEEGINALDAVIQLYNSINALRQQLPSDVRIHGVITEGGKAPNIIPD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCH
YAAARFFIRAATRQRCAEVTEKVKNIAQGAALATGTKVKIHQFQNEIDELLVTKTYNDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
AEELELLGEDVNRKERFGIGSTDAGNVSQVVPTIHPYIKIGPDDLIAHTNEFREAARSEL
HHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHC
GDKALITSAKALANTAYRLITEEGLLEKVKEEFREAQRNQG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GATGVASQRKTIEESIERNKEKYIETSHDIHANPEIGNQEFYASRTLSLLLGSAGFQLQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEE
HNIAGHETGFIARKSSGKQGPAIAFLAEYDALPGLGHACGHNLIGTISVAAAIALSETLE
ECCCCCCCCEEEECCCCCCCCEEEEEEHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
EIGGEVVVFGTPAEEGGPNGSAKSSYVKAGLFKNIDAALMIHPSGKTATTSPSLAVDPLD
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCE
FHFYGKTAHAAASPEEGINALDAVIQLYNSINALRQQLPSDVRIHGVITEGGKAPNIIPD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCH
YAAARFFIRAATRQRCAEVTEKVKNIAQGAALATGTKVKIHQFQNEIDELLVTKTYNDVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
AEELELLGEDVNRKERFGIGSTDAGNVSQVVPTIHPYIKIGPDDLIAHTNEFREAARSEL
HHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHC
GDKALITSAKALANTAYRLITEEGLLEKVKEEFREAQRNQG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-acyl-L-amino acid; H2O

Specific reaction: An N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9829935 [H]