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The map label for this gene is rfbG [H]

Identifier: 52142173

GI number: 52142173

Start: 3197356

End: 3198411

Strand: Direct

Name: rfbG [H]

Synonym: BCZK3070

Alternate gene names: 52142173

Gene position: 3197356-3198411 (Clockwise)

Preceding gene: 52142172

Following gene: 52142171

Centisome position: 60.32

GC content: 38.64

Gene sequence:

>1056_bases
ATGGCTTCATCATCTTTTTGGAATAAAAAAAAAGTATTTATTACGGGACATACTGGATTTAAAGGTTCCTGGCTCACCCT
TTTCTTAACTTCTTTAGGTGCAGAAGTAGTTGGCTTTTCTTCTCATCCCCCATCTATTCCTAACCTTTTTGAACAAGGTA
ACGTAGCAAAAGAATGCATAACAATTCATGGCAACATTACAGATTACGATTCTTTATTCCACACCCTAAAACAACATAAT
CCTGACATACTATTTCATTTAGCAGCCCAGCCAATCGTCACCACTTCATATAAAAATCCTATCGAAACATTTAAAACGAA
TGTTTTAGGAACTGTCCACGTGTTAGAGGCGGCAAAACATATAGAAAGTATACGTGGCATCATTAATGTTACAAGTGATA
AATGTTATGAAAATGACGGGAGCGGTAACCAGGCATTCGTGGAAAGTGACCGACTAGGCGGTTTTGACCCTTATAGTGCT
AGTAAAGCTTGCGCTGAAATAGTGGCAACATCCTATCATAAATCATTCTTCCGCACGAATACTCAGAAACTCGCTTCGGT
TAGAGCAGGTAACGTCATCGGCGGTGGTGATTGGGCAGAGGACCGATTATTCCCAGATATCATTCGTGCATATTTACAAG
ATGATACGTTAACTATTAGAAACAAAAATGCTATTCGCCCGTGGCAACACGTATTAGATCCTTTACACGGCTATATCCTT
TTAGCTGAAAAACTTTGGACAGACGCTGAATATGCAGAAGCATGGAATTTCGGCCCGTTGAACGAACCTAACAGAACCGT
TCATGATGTCATTCAATCTGTAATAAAATTATGGAATAAACAACTAACAATCACTTCCCCCTCTACAAACGCTCCTTATG
AATCGCCTGTTTTAACACTCGATAGTACAAAAGCAGTAAATAAACTCAACTGGACTCCTAAGTTATCAACAGATAACGCT
ATCGCTTGGACTGTTGATTGGTACAAACAATATGCATCCGGTGAAAATATAGAATCTTTCACGAGGCAACAAATCGATGC
ATTCAAAAATTTATAA

Upstream 100 bases:

>100_bases
CAACATGCTGGTTTTTGGCATCCGATGGATACATTGCGCGATAAAAATAAATTAGTCGAGCTATGGGAAAGTAATAACGC
TCCGTGGAAGGTTTGGTAAT

Downstream 100 bases:

>100_bases
GGGGGCTATAAAATGGAACAGAAAAAATGCCGTTTTTGCCACTCATTACTCACAAACACTTTTTTAGATTTAGGTGTTTC
TCCTCTCGCTAACTCATTTG

Product: CDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MASSSFWNKKKVFITGHTGFKGSWLTLFLTSLGAEVVGFSSHPPSIPNLFEQGNVAKECITIHGNITDYDSLFHTLKQHN
PDILFHLAAQPIVTTSYKNPIETFKTNVLGTVHVLEAAKHIESIRGIINVTSDKCYENDGSGNQAFVESDRLGGFDPYSA
SKACAEIVATSYHKSFFRTNTQKLASVRAGNVIGGGDWAEDRLFPDIIRAYLQDDTLTIRNKNAIRPWQHVLDPLHGYIL
LAEKLWTDAEYAEAWNFGPLNEPNRTVHDVIQSVIKLWNKQLTITSPSTNAPYESPVLTLDSTKAVNKLNWTPKLSTDNA
IAWTVDWYKQYASGENIESFTRQQIDAFKNL

Sequences:

>Translated_351_residues
MASSSFWNKKKVFITGHTGFKGSWLTLFLTSLGAEVVGFSSHPPSIPNLFEQGNVAKECITIHGNITDYDSLFHTLKQHN
PDILFHLAAQPIVTTSYKNPIETFKTNVLGTVHVLEAAKHIESIRGIINVTSDKCYENDGSGNQAFVESDRLGGFDPYSA
SKACAEIVATSYHKSFFRTNTQKLASVRAGNVIGGGDWAEDRLFPDIIRAYLQDDTLTIRNKNAIRPWQHVLDPLHGYIL
LAEKLWTDAEYAEAWNFGPLNEPNRTVHDVIQSVIKLWNKQLTITSPSTNAPYESPVLTLDSTKAVNKLNWTPKLSTDNA
IAWTVDWYKQYASGENIESFTRQQIDAFKNL
>Mature_350_residues
ASSSFWNKKKVFITGHTGFKGSWLTLFLTSLGAEVVGFSSHPPSIPNLFEQGNVAKECITIHGNITDYDSLFHTLKQHNP
DILFHLAAQPIVTTSYKNPIETFKTNVLGTVHVLEAAKHIESIRGIINVTSDKCYENDGSGNQAFVESDRLGGFDPYSAS
KACAEIVATSYHKSFFRTNTQKLASVRAGNVIGGGDWAEDRLFPDIIRAYLQDDTLTIRNKNAIRPWQHVLDPLHGYILL
AEKLWTDAEYAEAWNFGPLNEPNRTVHDVIQSVIKLWNKQLTITSPSTNAPYESPVLTLDSTKAVNKLNWTPKLSTDNAI
AWTVDWYKQYASGENIESFTRQQIDAFKNL

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=343, Percent_Identity=23.3236151603499, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI48994969, Length=342, Percent_Identity=26.0233918128655, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788353, Length=350, Percent_Identity=24.5714285714286, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786974, Length=350, Percent_Identity=24.8571428571429, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115532424, Length=337, Percent_Identity=24.0356083086053, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=332, Percent_Identity=23.4939759036145, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 39293; Mature: 39162

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSSFWNKKKVFITGHTGFKGSWLTLFLTSLGAEVVGFSSHPPSIPNLFEQGNVAKECI
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCHHHEECCCCCCCCHHHHHCCCCCCEEE
TIHGNITDYDSLFHTLKQHNPDILFHLAAQPIVTTSYKNPIETFKTNVLGTVHVLEAAKH
EEECCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IESIRGIINVTSDKCYENDGSGNQAFVESDRLGGFDPYSASKACAEIVATSYHKSFFRTN
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
TQKLASVRAGNVIGGGDWAEDRLFPDIIRAYLQDDTLTIRNKNAIRPWQHVLDPLHGYIL
HHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEE
LAEKLWTDAEYAEAWNFGPLNEPNRTVHDVIQSVIKLWNKQLTITSPSTNAPYESPVLTL
EHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEE
DSTKAVNKLNWTPKLSTDNAIAWTVDWYKQYASGENIESFTRQQIDAFKNL
CCCHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASSSFWNKKKVFITGHTGFKGSWLTLFLTSLGAEVVGFSSHPPSIPNLFEQGNVAKECI
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCHHHEECCCCCCCCHHHHHCCCCCCEEE
TIHGNITDYDSLFHTLKQHNPDILFHLAAQPIVTTSYKNPIETFKTNVLGTVHVLEAAKH
EEECCCCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IESIRGIINVTSDKCYENDGSGNQAFVESDRLGGFDPYSASKACAEIVATSYHKSFFRTN
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
TQKLASVRAGNVIGGGDWAEDRLFPDIIRAYLQDDTLTIRNKNAIRPWQHVLDPLHGYIL
HHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEE
LAEKLWTDAEYAEAWNFGPLNEPNRTVHDVIQSVIKLWNKQLTITSPSTNAPYESPVLTL
EHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEE
DSTKAVNKLNWTPKLSTDNAIAWTVDWYKQYASGENIESFTRQQIDAFKNL
CCCHHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]