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The map label for this gene is qor [C]

Identifier: 52142023

GI number: 52142023

Start: 3342359

End: 3343357

Strand: Direct

Name: qor [C]

Synonym: BCZK3221

Alternate gene names: 52142023

Gene position: 3342359-3343357 (Clockwise)

Preceding gene: 52142022

Following gene: 52142021

Centisome position: 63.05

GC content: 34.73

Gene sequence:

>999_bases
ATGAAAGCGATGATAATTGATAAGTACGGAAAAGTTCCAATGCGTATGGCCGAGGTACCTATTCCTGAAATAAATGAGCA
TGAAGTGCTCGCAGAAATTTATGCAGCTAGTATTAACCCAATTGATTTTAAAATACGCGATGGAAAAGTAAAGATGTTAC
TTAAATATGAAATGCCCCTAATCCTTGGGAATGACTTTGCCGGTGTCATCATAAAGGTTGGATCCAAAGTAACTCGTTTT
AAAGTCGGTGATGAAATATATGCACGTCCAAGAAAAAATAAGATTGGTACTTTCGCGGAGTATATAGCCATTCATGAAGA
TGATATAGCTTTAAAACCGAAAAATTTAAGTTTTGAAGAAGCTGCTTCAATTCCACTTGTTGGCTTAACATCATACCAAG
CATTACATGACATTATGCAATTACAAAAAGATCAAAAGATTTTAATTCACGCTGGATCTGGTGGTGTTGGTACTTTCGCA
ATTCAGTTAGCAAAAATAATGGGCGCTACCGTTACAACAACTGCTAGTGAAGCTGGTTCCGATTTAGTAAAGTCTCTTGG
AGCAGATCAAATTATTAATTACAAAACAGAAAAATTTGAAGAAATACTAAAAGATTATGATGCAGTATTTGATACCATTG
GTGGTACAACACTTGAAAAATCATTCGATATTATAAAAAGCGGCGGCAGCATTGTTTCCGTTTCAGGAATGCCAAATGCT
CGTTTCGGTAAAGAATTCGGTTCTGGATTTTTTAAAACATTCTTATTTTCATTAGCAAGTAAAAAACTTACTGCACTTGA
AAAAAAGCATAATGCTCAATATTCATTTTTATTTATGAAGCCAAGCGGGGATCAATTACGTATTATCGCAAATTATATTG
AAGCCGGAAAAATCAAACCGGTAATCGATCGCGTTTTCCCTTTTGAAGATGCGCAAAAAGCAATGGAATATTCAGAGGCC
GGAAGAGCAAAAGGAAAAATAATTGTAAAAATGAAATAA

Upstream 100 bases:

>100_bases
TGCCCATAAAAGTCCGATTGGTTCAACTAATAATCAGTGGGGGATGAAGAACCCCCCACTGATTAAAGTTTCACTTTATT
GAAATTTGGAGGTATAAGAA

Downstream 100 bases:

>100_bases
TAATAAAGACTCCATTTTCTTAAAATGGAGGTTTTAAATTTGCTGTTAAATAGACATAGTGTACTGAAGTCCTTACAATA
GATTGCAAGGGGAAATATCA

Product: alcohol dehydrogenase, zinc-containing

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIYAASINPIDFKIRDGKVKMLLKYEMPLILGNDFAGVIIKVGSKVTRF
KVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGSDLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGSIVSVSGMPNA
RFGKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKPVIDRVFPFEDAQKAMEYSEA
GRAKGKIIVKMK

Sequences:

>Translated_332_residues
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIYAASINPIDFKIRDGKVKMLLKYEMPLILGNDFAGVIIKVGSKVTRF
KVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGSDLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGSIVSVSGMPNA
RFGKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKPVIDRVFPFEDAQKAMEYSEA
GRAKGKIIVKMK
>Mature_332_residues
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIYAASINPIDFKIRDGKVKMLLKYEMPLILGNDFAGVIIKVGSKVTRF
KVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGSDLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGSIVSVSGMPNA
RFGKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKPVIDRVFPFEDAQKAMEYSEA
GRAKGKIIVKMK

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=358, Percent_Identity=35.7541899441341, Blast_Score=198, Evalue=5e-51,
Organism=Homo sapiens, GI22538446, Length=346, Percent_Identity=29.7687861271676, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI22538444, Length=346, Percent_Identity=29.7687861271676, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=29.6774193548387, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=28, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=28, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI194239676, Length=313, Percent_Identity=28.1150159744409, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=25.7879656160458, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI67078404, Length=334, Percent_Identity=24.5508982035928, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI67078406, Length=299, Percent_Identity=25.752508361204, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI28557745, Length=345, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI90669511, Length=157, Percent_Identity=30.5732484076433, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1790485, Length=318, Percent_Identity=32.3899371069182, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790045, Length=351, Percent_Identity=21.3675213675214, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789651, Length=246, Percent_Identity=26.0162601626016, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=366, Percent_Identity=29.2349726775956, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17507255, Length=238, Percent_Identity=30.672268907563, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71988145, Length=258, Percent_Identity=26.7441860465116, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536829, Length=282, Percent_Identity=28.3687943262411, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562876, Length=267, Percent_Identity=28.0898876404494, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17556000, Length=347, Percent_Identity=23.0547550432277, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323801, Length=341, Percent_Identity=27.8592375366569, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319520, Length=347, Percent_Identity=27.3775216138329, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320948, Length=369, Percent_Identity=24.1192411924119, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324195, Length=243, Percent_Identity=32.9218106995885, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319945, Length=284, Percent_Identity=30.2816901408451, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319401, Length=262, Percent_Identity=25.9541984732824, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323493, Length=242, Percent_Identity=30.9917355371901, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581341, Length=364, Percent_Identity=28.021978021978, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24581339, Length=364, Percent_Identity=28.021978021978, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45550423, Length=253, Percent_Identity=24.5059288537549, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330659, Length=233, Percent_Identity=27.4678111587983, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19920632, Length=233, Percent_Identity=27.4678111587983, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR014182
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36637; Mature: 36637

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIYAASINPIDFKIRDGKVKMLLKYEMPL
CCEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCE
ILGNDFAGVIIKVGSKVTRFKVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEE
EECCCCCEEEEEECCCEEEEECCCHHHCCCCCCCCHHHHHHHEEECCCCEECCCCCCHHH
AASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFAIQLAKIMGATVTTTASEAGS
HCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECHHHHHH
DLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGSIVSVSGMPNA
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCC
RFGKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEHHHCCCCCH
VIDRVFPFEDAQKAMEYSEAGRAKGKIIVKMK
HHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIYAASINPIDFKIRDGKVKMLLKYEMPL
CCEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCCE
ILGNDFAGVIIKVGSKVTRFKVGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEE
EECCCCCEEEEEECCCEEEEECCCHHHCCCCCCCCHHHHHHHEEECCCCEECCCCCCHHH
AASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFAIQLAKIMGATVTTTASEAGS
HCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECHHHHHH
DLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGSIVSVSGMPNA
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCC
RFGKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRIIANYIEAGKIKP
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEHHHCCCCCH
VIDRVFPFEDAQKAMEYSEAGRAKGKIIVKMK
HHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA