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The map label for this gene is ribH [H]

Identifier: 52141380

GI number: 52141380

Start: 3994824

End: 3995285

Strand: Direct

Name: ribH [H]

Synonym: BCZK3868

Alternate gene names: 52141380

Gene position: 3994824-3995285 (Clockwise)

Preceding gene: 52141383

Following gene: 52141373

Centisome position: 75.36

GC content: 39.61

Gene sequence:

>462_bases
ATGGTATTCGAAGGTCATTTAGTTGGTACAGGATTAAAAGTTGGGGTTGTTGTTGGACGTTTTAATGAATTTATTACAAG
TAAGTTACTAGGGGGCGCTTTAGATGGATTAAAGCGTCACGGTGTAGAAGAAAACGATATTGATGTTGCTTGGGTTCCTG
GCGCATTCGAAATTCCTTTAATCGCTAAAAAGATGGCGAATAGCGGGAAGTATGATGCTGTTATTACGTTAGGTACAGTA
ATTCGAGGTGCTACAACACATTACGATTATGTTTGTAATGAAGTAGCAAAAGGTGTTGCATCTTTATCACTTCAAACAGA
CATCCCAGTTATTTTCGGTGTATTAACGACAGAAACGATTGAGCAAGCGATTGAACGCGCGGGCACGAAAGCTGGTAATA
AAGGCTATGAATCTGCAGTTGCTGCAATTGAAATGGCTCACTTATCAAAACAATGGGCATAA

Upstream 100 bases:

>100_bases
GTTACAAATGCCAGCAAAAGAAGAGAATAAAACGTATTTACAAACGAAAGTAAACAAATTAGGACATTTACTAAACTTAT
AATTAAAGGAGAGATTTATT

Downstream 100 bases:

>100_bases
AAAAAAGAGGCTGCGGCCTCTTTTTATTTTTTTACTTTTTTCCGTACATCTTTTATTAATTCATCCATTGTTTTTCCTTC
TGTTTGTATACGAAGTGTTT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTV
IRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA

Sequences:

>Translated_153_residues
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTV
IRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
>Mature_153_residues
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTV
IRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=150, Percent_Identity=54, Blast_Score=166, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6324429, Length=147, Percent_Identity=38.0952380952381, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16246; Mature: 16246

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPL
CEECCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHH
IAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETI
HHHHHCCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPL
CEECCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHH
IAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETI
HHHHHCCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA