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The map label for this gene is argD [H]

Identifier: 52141365

GI number: 52141365

Start: 4010120

End: 4011280

Strand: Reverse

Name: argD [H]

Synonym: BCZK3884

Alternate gene names: 52141365

Gene position: 4011280-4010120 (Counterclockwise)

Preceding gene: 52141364

Following gene: 52141366

Centisome position: 75.67

GC content: 38.42

Gene sequence:

>1161_bases
ATGATAAGTCATCTTTTTCAAACGTATGGGAGAAGAAAGATTGAGTTTGTAAAGGGAAAAGGAACGAAAGTCATTGATAA
TAACGGTAAGCAATATTTAGATTTCACATCAGGAATCGGTGTATGTAATTTAGGACATTGTCATCCTACTGTTATGAAAG
CTGTACAAGAGCAACTTAAAGATATATGGCATATATCTAACCTGTTTACGAGCAGCTTACAAGAAGAAGTCGCTTCATTA
TTAACAGAAAATATAGCATTAGATTATGTGTTCTTCTGTAATAGCGGGGCAGAGGCGAATGAAGCTGCTTTGAAGCTAGC
CCGTAAGCATACTGAAAAATCTCTCGTCGTAACATGCGAGCAATCTTTTCACGGTAGAACATTCGGAACGATGAGTGCGA
CGGGACAAAATAAAGTGAAAGAAGGATTTGGTCCGCTCCTTCCGTCTTTTTTACATACTCCATTTAACGATATAAAGGCG
CTCAAGGAAGTAATGAATGAAGAAGTTGCGGCAGTAATGGTAGAAGTTGTTCAAGGAGAGGGAGGAGTCAAACCTGCTGA
TCTATCCTTTTTGAAAGAGATTGAAACATTATGTAAGAAGTTCGGGTCTTTATTTATTATAGACGAAGTCCAAACAGGGA
TCGGAAGAACAGGGACACTATTTGCTTACGAACAAATGGGAATAAAACCTGATATTGTTACCGTGGCAAAGGCACTTGGA
AACGGGATTCCTGTAGGAGCGATGATTGGCCGGAAAGAACTTGGAACGTCGTTCACTGCAGGATCACACGGTTCAACGTT
TGGCGGAAATTATGTTGCAATGGCTGCAGCGAAAGAAGTATTGCAAGTAAGTAAAAGACCATCGTTTTTAAAAGAAGTAC
AAGAAAAGGGTGAGTACGTATTACAGAAGTTGCAAGAGGAATTACGACATGTCGAATGTATCCAAAATATACGTGGTAAA
GGGCTTATGATTGGAATTGAATGTACGCATGAAGTTGCAAGTTTTATAGAACAACTAGAAAAAGAGGGACTTCTCGTATT
ACAAGCAGGGCCTAATGTGATAAGACTATTACCGCCACTCATTGTAACGAATGAAGAGTTAGAACAGGCAGTATATATGA
TAAAAAAAGTAGTTTGTACAAAAAACGTATCAATTATATAA

Upstream 100 bases:

>100_bases
TGGGAGTGCAAAAGGTTAGTATCGTAAATGGGATGAAGGATTTTACCGAGGTTACAGGTGAGTGTATCGGAACGACGGTA
ACGAGGGGCGTGAGTATTGC

Downstream 100 bases:

>100_bases
GGGGGAAGTTTCATGTCAACTGTACAAGTACCGAAATTAAATACGAAAGATCTTTTAACATTAGAAGAACTAACGCAAGA
AGAAATTATTTCTTTAATTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MISHLFQTYGRRKIEFVKGKGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLKDIWHISNLFTSSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTEKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVKPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIKPDIVTVAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRPSFLKEVQEKGEYVLQKLQEELRHVECIQNIRGK
GLMIGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII

Sequences:

>Translated_386_residues
MISHLFQTYGRRKIEFVKGKGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLKDIWHISNLFTSSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTEKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVKPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIKPDIVTVAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRPSFLKEVQEKGEYVLQKLQEELRHVECIQNIRGK
GLMIGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII
>Mature_386_residues
MISHLFQTYGRRKIEFVKGKGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLKDIWHISNLFTSSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTEKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVKPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIKPDIVTVAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRPSFLKEVQEKGEYVLQKLQEELRHVECIQNIRGK
GLMIGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=32.2164948453608, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=30.8755760368664, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=33.8870431893688, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI37574042, Length=415, Percent_Identity=28.1927710843373, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI24119277, Length=410, Percent_Identity=27.3170731707317, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=28.1578947368421, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI226442705, Length=410, Percent_Identity=27.5609756097561, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI188536080, Length=416, Percent_Identity=22.3557692307692, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679950, Length=416, Percent_Identity=22.3557692307692, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679946, Length=416, Percent_Identity=22.3557692307692, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1789759, Length=376, Percent_Identity=40.9574468085106, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1788044, Length=361, Percent_Identity=42.1052631578947, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI145693181, Length=395, Percent_Identity=35.6962025316456, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=33.8383838383838, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1787560, Length=386, Percent_Identity=33.160621761658, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1786991, Length=399, Percent_Identity=28.3208020050125, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786349, Length=339, Percent_Identity=29.4985250737463, Blast_Score=127, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=384, Percent_Identity=34.8958333333333, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=32.258064516129, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=376, Percent_Identity=31.6489361702128, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=412, Percent_Identity=31.0679611650485, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI71981843, Length=172, Percent_Identity=31.9767441860465, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=23.2876712328767, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71992985, Length=99, Percent_Identity=35.3535353535354, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=35.969387755102, Blast_Score=248, Evalue=9e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=404, Percent_Identity=34.4059405940594, Blast_Score=217, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6324386, Length=283, Percent_Identity=26.5017667844523, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=369, Percent_Identity=25.7452574525745, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=31.8652849740933, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI161085790, Length=403, Percent_Identity=31.5136476426799, Blast_Score=187, Evalue=7e-48,
Organism=Drosophila melanogaster, GI28574759, Length=403, Percent_Identity=31.5136476426799, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=30.8823529411765, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI281366494, Length=418, Percent_Identity=25.1196172248804, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667139, Length=418, Percent_Identity=25.1196172248804, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667143, Length=418, Percent_Identity=25.1196172248804, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42324; Mature: 42324

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHLFQTYGRRKIEFVKGKGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLK
CHHHHHHHCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
DIWHISNLFTSSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTEKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGVKPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIKPDIVTVAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRPSFLKEVQEKGEYV
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELRHVECIQNIRGKGLMIGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCH
IVTNEELEQAVYMIKKVVCTKNVSII
HCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MISHLFQTYGRRKIEFVKGKGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLK
CHHHHHHHCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
DIWHISNLFTSSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTEKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGVKPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIKPDIVTVAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRPSFLKEVQEKGEYV
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELRHVECIQNIRGKGLMIGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCH
IVTNEELEQAVYMIKKVVCTKNVSII
HCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]