Click here to switch to the map view.

The map label for this gene is comEB [H]

Identifier: 52141178

GI number: 52141178

Start: 4182953

End: 4183510

Strand: Reverse

Name: comEB [H]

Synonym: BCZK4072

Alternate gene names: 52141178

Gene position: 4183510-4182953 (Counterclockwise)

Preceding gene: 52141176

Following gene: 52141179

Centisome position: 78.92

GC content: 35.13

Gene sequence:

>558_bases
ATGGAACGAATTTCATGGGATCAATATTTTATGACGCAAAGCCATTTGCTATCTTTACGTAGTACATGTACAAGGCTTGC
AGTAGGAGCAACAATCGTTCGTGATAAACGAATTATTGCTGGTGGATATAATGGTTCAATTAAAGGTGGCGTACATTGTA
TAGATGATGGATGCTACGTTATTGATAATCATTGTGTTCGTACAATTCACGCAGAAATGAATGCTTTGTTACAATGTGCA
AAATTTGGCGTGAAAACGGAGGAAGCGGAAATTTATGTTACGCATTTTCCGTGTTTACAATGTTGTAAGGCGATTATACA
AAGTGGTATTACAGCGGTTTATTATGCACAGGATTATAAAAATCATCCATATGCCGTAGAGTTATTTAAAAAAGCGAATG
TAACGGTGAAACACGTTCCGTTAGAATATGATATTGCAGCATTAGAGGATCAAAAGCGTCATATGGAGTTAAAAGAACTA
TTTGCATCTTTAGAAAAAGAGAACTTATCAATGGAAGAATTACAGCATGTATTCACGAAAGCAAAAATGATGCTATAA

Upstream 100 bases:

>100_bases
TCTGGAAAAAATAAAAGATCAAATTATTATTCCGTAAAAGATTGACGAAGTTTTTCTTCATTCGCTACACTACAAGTAGA
CAAAAAAGTAGGTGAAGAAT

Downstream 100 bases:

>100_bases
GGAGTGAGTATGAGTTGCAAGGACAATGGGGCTACGTTGCAATCTCATTTATAATAGGGATTGCAATCGCCTTCTCCTCT
TCAGTTGTATTGCTGACTTG

Product: ComE operon protein 2

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MERISWDQYFMTQSHLLSLRSTCTRLAVGATIVRDKRIIAGGYNGSIKGGVHCIDDGCYVIDNHCVRTIHAEMNALLQCA
KFGVKTEEAEIYVTHFPCLQCCKAIIQSGITAVYYAQDYKNHPYAVELFKKANVTVKHVPLEYDIAALEDQKRHMELKEL
FASLEKENLSMEELQHVFTKAKMML

Sequences:

>Translated_185_residues
MERISWDQYFMTQSHLLSLRSTCTRLAVGATIVRDKRIIAGGYNGSIKGGVHCIDDGCYVIDNHCVRTIHAEMNALLQCA
KFGVKTEEAEIYVTHFPCLQCCKAIIQSGITAVYYAQDYKNHPYAVELFKKANVTVKHVPLEYDIAALEDQKRHMELKEL
FASLEKENLSMEELQHVFTKAKMML
>Mature_185_residues
MERISWDQYFMTQSHLLSLRSTCTRLAVGATIVRDKRIIAGGYNGSIKGGVHCIDDGCYVIDNHCVRTIHAEMNALLQCA
KFGVKTEEAEIYVTHFPCLQCCKAIIQSGITAVYYAQDYKNHPYAVELFKKANVTVKHVPLEYDIAALEDQKRHMELKEL
FASLEKENLSMEELQHVFTKAKMML

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=150, Percent_Identity=34.6666666666667, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI61742821, Length=150, Percent_Identity=34.6666666666667, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321938, Length=142, Percent_Identity=37.3239436619718, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667298, Length=183, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24667302, Length=183, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 21080; Mature: 21080

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERISWDQYFMTQSHLLSLRSTCTRLAVGATIVRDKRIIAGGYNGSIKGGVHCIDDGCYV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEECCCCCCCCCCEEEECCCCEE
IDNHCVRTIHAEMNALLQCAKFGVKTEEAEIYVTHFPCLQCCKAIIQSGITAVYYAQDYK
ECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCC
NHPYAVELFKKANVTVKHVPLEYDIAALEDQKRHMELKELFASLEKENLSMEELQHVFTK
CCCCEEEEEHHCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AKMML
HHHCC
>Mature Secondary Structure
MERISWDQYFMTQSHLLSLRSTCTRLAVGATIVRDKRIIAGGYNGSIKGGVHCIDDGCYV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCEEEECCCCCCCCCCEEEECCCCEE
IDNHCVRTIHAEMNALLQCAKFGVKTEEAEIYVTHFPCLQCCKAIIQSGITAVYYAQDYK
ECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEECCCC
NHPYAVELFKKANVTVKHVPLEYDIAALEDQKRHMELKELFASLEKENLSMEELQHVFTK
CCCCEEEEEHHCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AKMML
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]