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The map label for this gene is can [H]

Identifier: 52140707

GI number: 52140707

Start: 4636940

End: 4637503

Strand: Reverse

Name: can [H]

Synonym: BCZK4546

Alternate gene names: 52140707

Gene position: 4637503-4636940 (Counterclockwise)

Preceding gene: 52140704

Following gene: 52140710

Centisome position: 87.48

GC content: 37.23

Gene sequence:

>564_bases
ATGAAGTCATTAGAAGAGATTTTGCAATACAATGAGAAATTTGTGGAAGAGAAAAAGTATGAAGAGTTTGTAGCGGGGAA
ATTTCCAAACAAAAAGATGGTAATTATTTCTTGTATGGATACAAGACTTGTTGAACTATTGCCGAAAGCGATGAATATGC
GTAACGGCGATGTGAAAATTATTAAAGTAGCAGGTGCTGTTATTTCACATCCTTTTGGAAGTATTATGCGTAGTATTTTA
GTCGCTGTATATGAACTTGGCGCTGATGAAGTATGTGTAGTTGGTCACCACGATTGTGGCATGGCAAAAATTCAAGCGAG
CAGTACAATTGAGAAAATGAAAGAGCGCGGTATAACAGAAGAAAAATTAGATATGCTTCGTTATTCTGGAATCGATTTAG
AACAATTCTTGCGCGGTTTCTCTAGTGTGGAAGAAAGTGTAGAACATAGCGTATCAGTACTTCGCAACCACCCATTACTT
CCGGAAGAAGTACCTGTTCACGGTCTTGTTATCGATCCTGATACAGGAAAATTAGATTTAGTTGTGAATGGTTACGACAA
TTAA

Upstream 100 bases:

>100_bases
AATATCTTATTTTTACTATAAAGCGATATCCTTTTTGAGTTTTTCATATTTTGGTACACTATTCATGTAGTGTAAACGAG
AGAAAAGAGGGCCTTTTACT

Downstream 100 bases:

>100_bases
GAATTTACTTTGTCATCCTTTTTATCTGGGACAGGATCAAATCCTCCTGGGTGGAAAGGGTGACATTTTAATATACGCTT
ACAAGTAAGCCAAAAGCCTT

Product: carbonic anhydrase; carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKSLEEILQYNEKFVEEKKYEEFVAGKFPNKKMVIISCMDTRLVELLPKAMNMRNGDVKIIKVAGAVISHPFGSIMRSIL
VAVYELGADEVCVVGHHDCGMAKIQASSTIEKMKERGITEEKLDMLRYSGIDLEQFLRGFSSVEESVEHSVSVLRNHPLL
PEEVPVHGLVIDPDTGKLDLVVNGYDN

Sequences:

>Translated_187_residues
MKSLEEILQYNEKFVEEKKYEEFVAGKFPNKKMVIISCMDTRLVELLPKAMNMRNGDVKIIKVAGAVISHPFGSIMRSIL
VAVYELGADEVCVVGHHDCGMAKIQASSTIEKMKERGITEEKLDMLRYSGIDLEQFLRGFSSVEESVEHSVSVLRNHPLL
PEEVPVHGLVIDPDTGKLDLVVNGYDN
>Mature_187_residues
MKSLEEILQYNEKFVEEKKYEEFVAGKFPNKKMVIISCMDTRLVELLPKAMNMRNGDVKIIKVAGAVISHPFGSIMRSIL
VAVYELGADEVCVVGHHDCGMAKIQASSTIEKMKERGITEEKLDMLRYSGIDLEQFLRGFSSVEESVEHSVSVLRNHPLL
PEEVPVHGLVIDPDTGKLDLVVNGYDN

Specific function: Reversible hydration of carbon dioxide [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 20966; Mature: 20966

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLEEILQYNEKFVEEKKYEEFVAGKFPNKKMVIISCMDTRLVELLPKAMNMRNGDVKI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEE
IKVAGAVISHPFGSIMRSILVAVYELGADEVCVVGHHDCGMAKIQASSTIEKMKERGITE
EEEHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCH
EKLDMLRYSGIDLEQFLRGFSSVEESVEHSVSVLRNHPLLPEEVPVHGLVIDPDTGKLDL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEE
VVNGYDN
EEECCCC
>Mature Secondary Structure
MKSLEEILQYNEKFVEEKKYEEFVAGKFPNKKMVIISCMDTRLVELLPKAMNMRNGDVKI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEE
IKVAGAVISHPFGSIMRSILVAVYELGADEVCVVGHHDCGMAKIQASSTIEKMKERGITE
EEEHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCH
EKLDMLRYSGIDLEQFLRGFSSVEESVEHSVSVLRNHPLLPEEVPVHGLVIDPDTGKLDL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEE
VVNGYDN
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]