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The map label for this gene is metQ [H]

Identifier: 52140549

GI number: 52140549

Start: 4805165

End: 4805971

Strand: Reverse

Name: metQ [H]

Synonym: BCZK4708

Alternate gene names: 52140549

Gene position: 4805971-4805165 (Counterclockwise)

Preceding gene: 52140546

Following gene: 52140550

Centisome position: 90.66

GC content: 34.45

Gene sequence:

>807_bases
ATGAAAAAGATTCTATTGTCAGTTGTTACAGCGCTGTCTGTATTTACATTAGCTGCTTGCGGGGGGAAAGAGGAGAATAA
GCTTGTCGTTGGAGCTTCTAACGTACCGCACGCTGTTATTTTAGAAAAGGTACAGCCGATATTAGAGAAAAAGGGAATTA
AATTAGAAATTAAAAAATTCCAAGATTATGTGTTGCCAAATAAGGCGTTAGCGGATAAGGAAATTGATGCAAACTACTTC
CAGCACATTCCGTATTTAGATAAAGAAATCCAAGAAAAAGGATATAAAATTGTAAACGCAGGAAAAATCCATTTAGAGCC
AATGGGTATTTATTCTAAGAGATATAAAAGCTTAAAAGACTTACCAGATGGCGGGACAGTAATTATGAGTAATAACGTAG
CGGAGCGTGGCCGTATGCTAGCATTGTTACAAAAAGGCGGCGTTATTAAATTAAAAGATGGAGTAGATGTTGTGAAAGCA
ACAGTAAAAGATGTTGTAGAAAACCCGAAAAACTTAAAGTTTAAAACAGATGTTGAGCCTGGACTTTCACCGAAGTTATA
TGAAAATAATGAAGGAGATGCTTTATTTATTAATTCAAACTATGCAATTGATGCAAAATTAAATCCAACAAAGGATGCAA
TTGCCATTGAAGGATCAGACTCTCCGTATGCAAATATTATTGCAGTTCGTAAAGGTGACGAGAAGAAAAAAGAAATTAAA
GAGCTAGTAGAAGTACTGCATTCAAAAGAAATTCAAGATTTTATTAATAAAGAATATAAAGGTGCTGTACTTCCGGTAAG
TGAATAA

Upstream 100 bases:

>100_bases
AGGGGCAGTTGTTCCTGTAAAAGAATAATTGCTGGGGAAGGGCTGGTGTATGCCGGCCCTTTTTATAACTACATAATTAT
ACGGGAGAAGGGGACATCAT

Downstream 100 bases:

>100_bases
ATATAAGGAAAGGACTGGGAAATTACCAGTCCTTTTTTCTTTATATAAATAAGAAGAAAGGTGTATCATAGAAAGATGTG
AAGGAAATACTTATATACAT

Product: ABC transporter, substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKKILLSVVTALSVFTLAACGGKEENKLVVGASNVPHAVILEKVQPILEKKGIKLEIKKFQDYVLPNKALADKEIDANYF
QHIPYLDKEIQEKGYKIVNAGKIHLEPMGIYSKRYKSLKDLPDGGTVIMSNNVAERGRMLALLQKGGVIKLKDGVDVVKA
TVKDVVENPKNLKFKTDVEPGLSPKLYENNEGDALFINSNYAIDAKLNPTKDAIAIEGSDSPYANIIAVRKGDEKKKEIK
ELVEVLHSKEIQDFINKEYKGAVLPVSE

Sequences:

>Translated_268_residues
MKKILLSVVTALSVFTLAACGGKEENKLVVGASNVPHAVILEKVQPILEKKGIKLEIKKFQDYVLPNKALADKEIDANYF
QHIPYLDKEIQEKGYKIVNAGKIHLEPMGIYSKRYKSLKDLPDGGTVIMSNNVAERGRMLALLQKGGVIKLKDGVDVVKA
TVKDVVENPKNLKFKTDVEPGLSPKLYENNEGDALFINSNYAIDAKLNPTKDAIAIEGSDSPYANIIAVRKGDEKKKEIK
ELVEVLHSKEIQDFINKEYKGAVLPVSE
>Mature_268_residues
MKKILLSVVTALSVFTLAACGGKEENKLVVGASNVPHAVILEKVQPILEKKGIKLEIKKFQDYVLPNKALADKEIDANYF
QHIPYLDKEIQEKGYKIVNAGKIHLEPMGIYSKRYKSLKDLPDGGTVIMSNNVAERGRMLALLQKGGVIKLKDGVDVVKA
TVKDVVENPKNLKFKTDVEPGLSPKLYENNEGDALFINSNYAIDAKLNPTKDAIAIEGSDSPYANIIAVRKGDEKKKEIK
ELVEVLHSKEIQDFINKEYKGAVLPVSE

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable) [H]

COG id: COG1464

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface antigen

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpA lipoprotein family [H]

Homologues:

Organism=Escherichia coli, GI1786396, Length=265, Percent_Identity=38.8679245283019, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1790093, Length=217, Percent_Identity=33.1797235023041, Blast_Score=134, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004872 [H]

Pfam domain/function: PF03180 Lipoprotein_9 [H]

EC number: NA

Molecular weight: Translated: 29657; Mature: 29657

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLSVVTALSVFTLAACGGKEENKLVVGASNVPHAVILEKVQPILEKKGIKLEIKKF
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHH
QDYVLPNKALADKEIDANYFQHIPYLDKEIQEKGYKIVNAGKIHLEPMGIYSKRYKSLKD
HHHHCCCCHHCCCCCCCHHHHHCCCHHHHHHHCCCEEEECCEEEEEECCHHHHHHHHHHC
LPDGGTVIMSNNVAERGRMLALLQKGGVIKLKDGVDVVKATVKDVVENPKNLKFKTDVEP
CCCCCEEEEECCHHHHHHEEEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCC
GLSPKLYENNEGDALFINSNYAIDAKLNPTKDAIAIEGSDSPYANIIAVRKGDEKKKEIK
CCCCCEEECCCCCEEEEECCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHH
ELVEVLHSKEIQDFINKEYKGAVLPVSE
HHHHHHHHHHHHHHHCHHHCCCEEECCC
>Mature Secondary Structure
MKKILLSVVTALSVFTLAACGGKEENKLVVGASNVPHAVILEKVQPILEKKGIKLEIKKF
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEHH
QDYVLPNKALADKEIDANYFQHIPYLDKEIQEKGYKIVNAGKIHLEPMGIYSKRYKSLKD
HHHHCCCCHHCCCCCCCHHHHHCCCHHHHHHHCCCEEEECCEEEEEECCHHHHHHHHHHC
LPDGGTVIMSNNVAERGRMLALLQKGGVIKLKDGVDVVKATVKDVVENPKNLKFKTDVEP
CCCCCEEEEECCHHHHHHEEEEECCCCEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCC
GLSPKLYENNEGDALFINSNYAIDAKLNPTKDAIAIEGSDSPYANIIAVRKGDEKKKEIK
CCCCCEEECCCCCEEEEECCEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHH
ELVEVLHSKEIQDFINKEYKGAVLPVSE
HHHHHHHHHHHHHHHCHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]