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The map label for this gene is metQ [H]

Identifier: 52140546

GI number: 52140546

Start: 4806044

End: 4806856

Strand: Reverse

Name: metQ [H]

Synonym: BCZK4709

Alternate gene names: 52140546

Gene position: 4806856-4806044 (Counterclockwise)

Preceding gene: 52140547

Following gene: 52140549

Centisome position: 90.68

GC content: 33.09

Gene sequence:

>813_bases
ATGAAAAAATTATTACTGACAGCACTTATTTCAACTTCAATTTTTGGGTTAGCTGCTTGTGGTGGGAAAGATAACGATGA
AAAGAAACTAGTTGTTGGTGCTTCTAACGTACCGCACGCTGAAATTTTAGAAAAGGCAAAACCGTTACTTGAGAAAAAAG
GAATTGAATTAGAAGTGAAAAAATTCCAAGATTACGTGTTGCCAAATAAATCGCTGGCGGATAAAGATTTAGATGCTAAC
TATTTCCAGCACATTCCGTATTTAGAAAAAGAAATTAAAGATAAAAAATATGATTTTGAAGTAGCAGGAAAAATTCATTT
AGAACCAATTGGCGTATATTCTCAAAAATATAAGAGCTTAAAAGAGCTTCCAGACGGAGCGACAATTATTATGAGTAATT
CAGTTGCTGACCATGGACGTGGTTTAGCAATTTTACAAAAAGAAGGTATTTTAAAAATTAAAGACGGAGTAGATCCAGTT
AAAGCAACTCCGAAAGATATCGCGGATAATCCGAAAAACTTAAAATTCAAAACGGATATTGAGCCTGGTTTATTACCACA
AGTGTATAACAATAAAGAAGGCGACGCTGTTTTAATTAACTCAAACTATGCAATCGATGCGAAGTTAAATCCAGAAAAAG
ATGCAATTGCAATTGAAAGCAATGATTCACCGTACGCAAACGTAGTAGCTGTTCGTAAAGGCGATAAAGATAAAAAAGAA
ATTAAAGAGCTAGTAGAAGTGCTACATTCAAAAGAAATTGAAGACTTTATTAATAAAGAATATAAAGGGGCAGTTGTTCC
TGTAAAAGAATAA

Upstream 100 bases:

>100_bases
CAATTTGTGTATTACTAGTTGTATTTTTCATTCAGTGGATTGGTGATCGTGTAACGACTCGAATAGATAAACGATAATAA
AAAACGGGAGGATGTTTCAA

Downstream 100 bases:

>100_bases
TTGCTGGGGAAGGGCTGGTGTATGCCGGCCCTTTTTATAACTACATAATTATACGGGAGAAGGGGACATCATATGAAAAA
GATTCTATTGTCAGTTGTTA

Product: ABC transporter, substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDLDAN
YFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGVDPV
KATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKDKKE
IKELVEVLHSKEIEDFINKEYKGAVVPVKE

Sequences:

>Translated_270_residues
MKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDLDAN
YFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGVDPV
KATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKDKKE
IKELVEVLHSKEIEDFINKEYKGAVVPVKE
>Mature_270_residues
MKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVKKFQDYVLPNKSLADKDLDAN
YFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSLKELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGVDPV
KATPKDIADNPKNLKFKTDIEPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKDKKE
IKELVEVLHSKEIEDFINKEYKGAVVPVKE

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable) [H]

COG id: COG1464

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface antigen

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpA lipoprotein family [H]

Homologues:

Organism=Escherichia coli, GI1786396, Length=260, Percent_Identity=37.3076923076923, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1790093, Length=249, Percent_Identity=31.7269076305221, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004872 [H]

Pfam domain/function: PF03180 Lipoprotein_9 [H]

EC number: NA

Molecular weight: Translated: 29920; Mature: 29920

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVK
CHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
KFQDYVLPNKSLADKDLDANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSL
HHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCEEEECEEEEEECCHHHHHHHHH
KELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGVDPVKATPKDIADNPKNLKFKTDI
HHCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHCCCCCCCEEEECC
EPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKDKKE
CCCCCCHHHCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCHHH
IKELVEVLHSKEIEDFINKEYKGAVVPVKE
HHHHHHHHHHHHHHHHHCCCCCCCEEEECC
>Mature Secondary Structure
MKKLLLTALISTSIFGLAACGGKDNDEKKLVVGASNVPHAEILEKAKPLLEKKGIELEVK
CHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEE
KFQDYVLPNKSLADKDLDANYFQHIPYLEKEIKDKKYDFEVAGKIHLEPIGVYSQKYKSL
HHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCEEEECEEEEEECCHHHHHHHHH
KELPDGATIIMSNSVADHGRGLAILQKEGILKIKDGVDPVKATPKDIADNPKNLKFKTDI
HHCCCCEEEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCHHHCCCCCCCEEEECC
EPGLLPQVYNNKEGDAVLINSNYAIDAKLNPEKDAIAIESNDSPYANVVAVRKGDKDKKE
CCCCCCHHHCCCCCCEEEEECCEEEEEEECCCCCEEEEECCCCCCEEEEEEECCCCCHHH
IKELVEVLHSKEIEDFINKEYKGAVVPVKE
HHHHHHHHHHHHHHHHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]