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The map label for this gene is yybE [H]

Identifier: 52140346

GI number: 52140346

Start: 5004115

End: 5004999

Strand: Direct

Name: yybE [H]

Synonym: BCZK4914

Alternate gene names: 52140346

Gene position: 5004115-5004999 (Clockwise)

Preceding gene: 52140348

Following gene: 52140342

Centisome position: 94.4

GC content: 37.85

Gene sequence:

>885_bases
ATGGAACTTCTTCAACTAAAATACTTTCAGACAGTTGCAAGATTAGAGCATATGACAAAAGCCGCTGAAGAATTGCATAT
CGCACAACCTTCGCTCAGCAAAACAATTGCTAGATTAGAAAAGGACTTAGGCGTTCCGTTATTTGACCGCCAAGGGCGAC
AAATTACATTAAACTCTTTCGGGAAAGTATTTTTAAAACGAGTAGAGCGCATTTTTCATGAATTAAGTGAAGGCGAACGA
GAAATTAAAGATTTAGCTGACTTACAACAAAGCTCTATTACGCTGGCTGTTTCTATTCCAAGAATATTACCCGAACTAAT
CGGTTCCTTTTTACTAGAACATCCTAACGTTCGATTCCAACAGTTTCTCGCATCTACTCCTTCTATGAAACGACAACTAG
ATAATATAGAAATTGACTTTTGCATTTCTTCTGTGCCAATTGAAGGCGAAGAGATTATTTGGGAACCACTTATTACAGAA
GAAATTTTCTTAGTCGTCCCTTCAGGTCATCGTTTATCAGAACGTGAAAGTATCTATCTACATGAAGTAAAAGACGAACC
GTTCATTAGTATGAACACTGGTTATGGATTTCGGCACTTAACAGATGAATTTTGTAAAGAAGCTGGCTTCACTCCACATA
TCGCTTTTGAAGTAGATGAACCAACCGTAATTAGCGACCTTATTAAGCAAGGCCTCGGCATCGCCTTTGTCCCAAGTTTA
ACTTTACTAAAAAACTCTACTTTAGCATTAAATAAGTTACGTATTATTGAACCCGTTTGTAAGCGAACGATTGGCTTAAG
CTGGTCAAAAAAACGCTACTTATCGAAAACCGCCCAGCAATTCCGTGAATTCGTGATCGATTACTTCTCCAATATTAAGG
CGTAA

Upstream 100 bases:

>100_bases
AATGGTTTAACAGATTTACTATACACGTCCACTTCCATACTGTATAATACATCTTTAATTATCAATTCATTCCTTTTGGT
CTATAGAAAGGAGAATCAAA

Downstream 100 bases:

>100_bases
AATGATATCAAAAAACAAAAGGTGCCATCCCGATAGGATGGCACCTTCTATTGTTCACTTTTCTCTAATTCTATTTCAGC
TAAAAGCGGTAGTACGTTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNSFGKVFLKRVERIFHELSEGER
EIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITE
EIFLVVPSGHRLSERESIYLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLALNKLRIIEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA

Sequences:

>Translated_294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNSFGKVFLKRVERIFHELSEGER
EIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITE
EIFLVVPSGHRLSERESIYLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLALNKLRIIEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA
>Mature_294_residues
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNSFGKVFLKRVERIFHELSEGER
EIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQQFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITE
EIFLVVPSGHRLSERESIYLHEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
TLLKNSTLALNKLRIIEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=30.0699300699301, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI145693105, Length=295, Percent_Identity=26.4406779661017, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=25.2559726962457, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=29.7619047619048, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=27.5720164609054, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=27.3648648648649, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=24.4, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788748, Length=303, Percent_Identity=25.4125412541254, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788296, Length=247, Percent_Identity=27.5303643724696, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789204, Length=270, Percent_Identity=24.4444444444444, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=285, Percent_Identity=23.1578947368421, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=26.4, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=172, Percent_Identity=29.6511627906977, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788297, Length=299, Percent_Identity=22.4080267558528, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081904, Length=259, Percent_Identity=28.957528957529, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790208, Length=289, Percent_Identity=24.9134948096886, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789506, Length=298, Percent_Identity=23.8255033557047, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33716; Mature: 33716

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNSF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEHHHH
GKVFLKRVERIFHELSEGEREIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHH
QFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITEEIFLVVPSGHRLSERESIYL
HHHHCCCHHHHHHCCCEEEEEEECCCCCCCHHEECCCCCCEEEEEECCCCCCCCCCCEEE
HEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEECCCH
TLLKNSTLALNKLRIIEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELLQLKYFQTVARLEHMTKAAEELHIAQPSLSKTIARLEKDLGVPLFDRQGRQITLNSF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEHHHH
GKVFLKRVERIFHELSEGEREIKDLADLQQSSITLAVSIPRILPELIGSFLLEHPNVRFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHCCCCHHHH
QFLASTPSMKRQLDNIEIDFCISSVPIEGEEIIWEPLITEEIFLVVPSGHRLSERESIYL
HHHHCCCHHHHHHCCCEEEEEEECCCCCCCHHEECCCCCCEEEEEECCCCCCCCCCCEEE
HEVKDEPFISMNTGYGFRHLTDEFCKEAGFTPHIAFEVDEPTVISDLIKQGLGIAFVPSL
EECCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEECCCH
TLLKNSTLALNKLRIIEPVCKRTIGLSWSKKRYLSKTAQQFREFVIDYFSNIKA
HHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]