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The map label for this gene is uvsE [H]

Identifier: 52140215

GI number: 52140215

Start: 5147322

End: 5148299

Strand: Direct

Name: uvsE [H]

Synonym: BCZK5047

Alternate gene names: 52140215

Gene position: 5147322-5148299 (Clockwise)

Preceding gene: 52140214

Following gene: 52140213

Centisome position: 97.1

GC content: 33.95

Gene sequence:

>978_bases
ATGCATAAAGGATGTGTATTCATTATGATTATGCGGTTCGGATATGTCTCACATGCAATGGCACTCTGGGACTGCTCTCC
GGCTAAAACGATAACATTTACAAGCTTTCAAAAGCTCAGTAAACAAGAGCGAGAAGATAAATTATACGATGTTACAAAAC
AAAATCTTGAGCATACAATACGTATTCTCCATTACAATATAGCTCATGAAATTCCGTTATATCGCTTGTCTTCTTCCATC
GTCCCACTTGCAACACATCCCGAAGTCGAGTTTGATTATATCGGGGCATTTACACCGCTTTGGCGTAAAATTGGGGCATT
AATTAAAGAACATAATTTAAGAGTAAGTTTTCATCCAAATCAATTTACACTATTTACAAGCGACAAACCACATATTACGA
CTAACGCTATTACAGATATGAACTATCATTATAAAGTATTAGATGCAATAGGCATTGCAGATTCTTCTTATATTAACATC
CATGTAGGTGGGGCCTACGGAAATAAAGAAAAAGCAATCGAGCGTTTCCATGAAAACATAAAAAAACTTCCTGCACATAT
AAAAAAGCAAATGACACTTGAAAATGATGATAAAACATATACAACTGCTGAAACGTTATCTATTTGCCAAAAAGAAAAGA
TCCCATTCGTATTTGATTATCACCATCACATGGCAAATCTTTGCGAGGAACCGTTAGAAGAGTTACTTCCTGCAATTTTT
GAAACTTGGTCACATACAAATATCGTTCCTAAAGTTCACATTTCCTCTCCTAAATCAAAAAAAGAATTTAGGGCTCACGC
GGAATATATTGATTTAGAGTTTATTAAACCTTTCTTACACGTTGCAAAAAAAATCAATCATAATTTCGATATTATGATTG
AAAGTAAACAGAAAGATTTAGCGATGCTGCAATTCATACATGAATTATCCTCTATAAGAGGGATAAAAAGAATAAGTAGC
TCAACATTACAATGGTAA

Upstream 100 bases:

>100_bases
CATCATTACTTTCCTTTAAAGATGTTAGCCCGCATTCTCTTATTGATAGAGGAAAAGAATGGATAGGAACAATACTCGCT
TTCTTCCTATAGGAAAGATA

Downstream 100 bases:

>100_bases
ATTGTAATGTTGAGCTATTTTTTTCAAAAAAAGTAATTTTTTTAGTAAAAAACACCCTATTTTATATGCTATGATTGGAA
TTAGCATTTTCCACCTGTGA

Product: putative UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSI
VPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRVSFHPNQFTLFTSDKPHITTNAITDMNYHYKVLDAIGIADSSYINI
HVGGAYGNKEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIHELSSIRGIKRISS
STLQW

Sequences:

>Translated_325_residues
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSI
VPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRVSFHPNQFTLFTSDKPHITTNAITDMNYHYKVLDAIGIADSSYINI
HVGGAYGNKEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIHELSSIRGIKRISS
STLQW
>Mature_325_residues
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSI
VPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRVSFHPNQFTLFTSDKPHITTNAITDMNYHYKVLDAIGIADSSYINI
HVGGAYGNKEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIHELSSIRGIKRISS
STLQW

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 37803; Mature: 37803

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTI
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILHYNIAHEIPLYRLSSSIVPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRVSFHPN
HHHEEHHHHCCCCEECCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCC
QFTLFTSDKPHITTNAITDMNYHYKVLDAIGIADSSYINIHVGGAYGNKEKAIERFHENI
EEEEEECCCCCEEECEEECCCCCEEEHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
KKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
HHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDL
HHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
AMLQFIHELSSIRGIKRISSSTLQW
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTI
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILHYNIAHEIPLYRLSSSIVPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRVSFHPN
HHHEEHHHHCCCCEECCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCC
QFTLFTSDKPHITTNAITDMNYHYKVLDAIGIADSSYINIHVGGAYGNKEKAIERFHENI
EEEEEECCCCCEEECEEECCCCCEEEHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
KKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
HHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDL
HHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
AMLQFIHELSSIRGIKRISSSTLQW
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA