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The map label for this gene is rnpA

Identifier: 51894474

GI number: 51894474

Start: 3565116

End: 3565463

Strand: Reverse

Name: rnpA

Synonym: STH3340

Alternate gene names: 51894474

Gene position: 3565463-3565116 (Counterclockwise)

Preceding gene: 51894475

Following gene: 51894473

Centisome position: 99.98

GC content: 65.8

Gene sequence:

>348_bases
ATGAAGAAGGCTTATCGGCTGAAATCGCGGCTGGCTTTCCAGTCGGTGTACGCACAGGGGCGTTCTGTCGCCAACCGGGC
TGCGGTCGTCCACGTCCTGAAACAGCAGGCGGGGACGCCTACCCGGGTTGGTTTCGCGGCAGGACGGAAGCTCGGCAAGG
CCGTGGTGCGCAACCGGGCGAAGCGGCGCCTGCGTGAGGCCGTGCGCCTCCTCTGGCCGCGCGTCCGGCAGGGATACTAC
ATTGTGGTCATCGCCCGCCAGGCAGCGCTGGACATGCCGTTCCCGGAACTCCGGCAGAAGGTCGAGGAACTCTTTGAACG
GGCGGGTCTTCTGCAGCGGGAAGGATAG

Upstream 100 bases:

>100_bases
CGTATAAGCCGCGACGGCCTCCCGTCGTGGCTCTTTTTCCATAAAAGGAGCGGATGGAGAGGGAAGCGCCGGCCTGCCGG
CGAATCCTCTCCCGACACGG

Downstream 100 bases:

>100_bases
ACGGTCATGACGCGTCTTCTGATGCTGCTGGTGCGCTTCTACCAGCGGTACCTCTCGCCGCTCAAGGGCGGACCGACGTG
CCGCTTTACCCCTTCCTGCT

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MKKAYRLKSRLAFQSVYAQGRSVANRAAVVHVLKQQAGTPTRVGFAAGRKLGKAVVRNRAKRRLREAVRLLWPRVRQGYY
IVVIARQAALDMPFPELRQKVEELFERAGLLQREG

Sequences:

>Translated_115_residues
MKKAYRLKSRLAFQSVYAQGRSVANRAAVVHVLKQQAGTPTRVGFAAGRKLGKAVVRNRAKRRLREAVRLLWPRVRQGYY
IVVIARQAALDMPFPELRQKVEELFERAGLLQREG
>Mature_115_residues
MKKAYRLKSRLAFQSVYAQGRSVANRAAVVHVLKQQAGTPTRVGFAAGRKLGKAVVRNRAKRRLREAVRLLWPRVRQGYY
IVVIARQAALDMPFPELRQKVEELFERAGLLQREG

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_SYMTH (Q67J29)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_077165.1
- ProteinModelPortal:   Q67J29
- SMR:   Q67J29
- GeneID:   2980993
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH3340
- NMPDR:   fig|292459.1.peg.3206
- HOGENOM:   HBG728160
- OMA:   CAEMERV
- BioCyc:   STHE292459:STH3340-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13144; Mature: 13144

Theoretical pI: Translated: 12.23; Mature: 12.23

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAYRLKSRLAFQSVYAQGRSVANRAAVVHVLKQQAGTPTRVGFAAGRKLGKAVVRNRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KRRLREAVRLLWPRVRQGYYIVVIARQAALDMPFPELRQKVEELFERAGLLQREG
HHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKAYRLKSRLAFQSVYAQGRSVANRAAVVHVLKQQAGTPTRVGFAAGRKLGKAVVRNRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
KRRLREAVRLLWPRVRQGYYIVVIARQAALDMPFPELRQKVEELFERAGLLQREG
HHHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA