Click here to switch to the map view.

The map label for this gene is yycF [H]

Identifier: 51894442

GI number: 51894442

Start: 3534680

End: 3535384

Strand: Reverse

Name: yycF [H]

Synonym: STH3308

Alternate gene names: 51894442

Gene position: 3535384-3534680 (Counterclockwise)

Preceding gene: 51894443

Following gene: 51894441

Centisome position: 99.14

GC content: 64.82

Gene sequence:

>705_bases
ATGGCCGATCGCATCCTGGTCGTGGACGATGAACGCCCTATTGCCGAAATCCTGAAGTTCAGCTTCGAACGCGAGGGTTT
TGAGGTGGAGATGGCCTTCGACGGCGAGGAGGCCGTGGCCAAGGCCCGTGCGTCTGACTTCGATCTCGTCATCCTTGACA
TCATGTTGCCCAAGCTGGACGGCTTCACGGTCTGCCGCGAGATCCGCCGCTTCTCCACCGTGCCGATCCTGATGCTGACG
GCCAAAGAGGACGAGGTGGACAAGGTCCTGGGGCTGGAGCTGGGAGCGGACGACTACGTGACCAAGCCCTTCAGCCCCCG
GGAGCTGATCGCGCGCGTGCGGGCGATCCTCAGGCGCACACGGGTGGCGGAGAGCAGCCGGTCGCGCACGGCTGCCGATG
AGATCCTGCGCGAGGGCGACATCACCATCAACCTGACCAGCTACGAGGTGCGCAAGGGCGACAAGCTGCTGGAGCTGACC
CCCCGGGAATTTGAGCTGCTCCGCTTCCTGATGGCCCACGCCGGCCAGGTCTTCTCGCGCGAGGCCCTGCTGGAGGAGGT
CTGGGGCTATGACTACTACGGCGACGTGCGCACGGTGGACGTGACCGTGCGGCGGCTCAGGGAGAAGCTGGAGGAGAACT
CTGCCAGGCCGGAGTACATCAAGACGCGGCGGGGGGTCGGCTACTACTTCCAGCGGTTCGACTGA

Upstream 100 bases:

>100_bases
CGACTGGCTGGATCAGGCCGAAGGGCGTTCCGCACAGGGAAGGAACGTACGCCTTTCGGAGCGAAAAGGCCTGCTGGAAG
AGAGATAAGGAGAGGACGTT

Downstream 100 bases:

>100_bases
CGGAGAGGGTGGACGTTGTGTTCCGCAGCATTCAGGGGAAGTTGGTGGTGGTCTACCTCCTCCTGATCGTGGTGGCCATG
GAGTTGGCGAGCCTCTACCT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MADRILVVDDERPIAEILKFSFEREGFEVEMAFDGEEAVAKARASDFDLVILDIMLPKLDGFTVCREIRRFSTVPILMLT
AKEDEVDKVLGLELGADDYVTKPFSPRELIARVRAILRRTRVAESSRSRTAADEILREGDITINLTSYEVRKGDKLLELT
PREFELLRFLMAHAGQVFSREALLEEVWGYDYYGDVRTVDVTVRRLREKLEENSARPEYIKTRRGVGYYFQRFD

Sequences:

>Translated_234_residues
MADRILVVDDERPIAEILKFSFEREGFEVEMAFDGEEAVAKARASDFDLVILDIMLPKLDGFTVCREIRRFSTVPILMLT
AKEDEVDKVLGLELGADDYVTKPFSPRELIARVRAILRRTRVAESSRSRTAADEILREGDITINLTSYEVRKGDKLLELT
PREFELLRFLMAHAGQVFSREALLEEVWGYDYYGDVRTVDVTVRRLREKLEENSARPEYIKTRRGVGYYFQRFD
>Mature_233_residues
ADRILVVDDERPIAEILKFSFEREGFEVEMAFDGEEAVAKARASDFDLVILDIMLPKLDGFTVCREIRRFSTVPILMLTA
KEDEVDKVLGLELGADDYVTKPFSPRELIARVRAILRRTRVAESSRSRTAADEILREGDITINLTSYEVRKGDKLLELTP
REFELLRFLMAHAGQVFSREALLEEVWGYDYYGDVRTVDVTVRRLREKLEENSARPEYIKTRRGVGYYFQRFD

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=44.206008583691, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=41.7391304347826, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.4736842105263, Blast_Score=170, Evalue=6e-44,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=40.5286343612335, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=40.7894736842105, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=39.1304347826087, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=36.7256637168142, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=39.7379912663755, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=35.5263157894737, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=34.1991341991342, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=35.0877192982456, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=35.3448275862069, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.5132743362832, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=33.1877729257642, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=37.037037037037, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790437, Length=118, Percent_Identity=33.0508474576271, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788191, Length=126, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27142; Mature: 27011

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRILVVDDERPIAEILKFSFEREGFEVEMAFDGEEAVAKARASDFDLVILDIMLPKLD
CCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHCCCCCCEEEEEHHHCCCC
GFTVCREIRRFSTVPILMLTAKEDEVDKVLGLELGADDYVTKPFSPRELIARVRAILRRT
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
RVAESSRSRTAADEILREGDITINLTSYEVRKGDKLLELTPREFELLRFLMAHAGQVFSR
HHHHHHCHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
EALLEEVWGYDYYGDVRTVDVTVRRLREKLEENSARPEYIKTRRGVGYYFQRFD
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHCCCC
>Mature Secondary Structure 
ADRILVVDDERPIAEILKFSFEREGFEVEMAFDGEEAVAKARASDFDLVILDIMLPKLD
CCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHCCCCCCEEEEEHHHCCCC
GFTVCREIRRFSTVPILMLTAKEDEVDKVLGLELGADDYVTKPFSPRELIARVRAILRRT
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
RVAESSRSRTAADEILREGDITINLTSYEVRKGDKLLELTPREFELLRFLMAHAGQVFSR
HHHHHHCHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHH
EALLEEVWGYDYYGDVRTVDVTVRRLREKLEENSARPEYIKTRRGVGYYFQRFD
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]