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The map label for this gene is yycG [H]

Identifier: 51894441

GI number: 51894441

Start: 3532881

End: 3534671

Strand: Reverse

Name: yycG [H]

Synonym: STH3307

Alternate gene names: 51894441

Gene position: 3534671-3532881 (Counterclockwise)

Preceding gene: 51894442

Following gene: 51894440

Centisome position: 99.12

GC content: 68.23

Gene sequence:

>1791_bases
GTGGACGTTGTGTTCCGCAGCATTCAGGGGAAGTTGGTGGTGGTCTACCTCCTCCTGATCGTGGTGGCCATGGAGTTGGC
GAGCCTCTACCTGATGCGCGAGCTGGAGCGCAGCTACATCGGCAAGGTCCAGGACGACCTGCACCAGAGCGCGCAGCTCC
TGGCGGGGCAGCTCACCAACTTCTTCGCGGGCGACCGCCTCGACCCCGAGGCGGTTGACCAGTATATGGAACGCTGGCCG
GGCGAGGTGCTGGTGCTCGACGCCAACGGCGTCGTCATCGGCGCTACGGCGCGCCTTTCCAACCGGGAGGAGCTCCTGGG
GCTGAAGTTCAGCCATGACGACGTCTCCCCCGCGTTCTTCGGCAACACCAACCGGCGGATCGGCAAGGAAGGCTCACAGC
GGATGGCCTACGAGGCGGTGCCGATCACCGTGGCCGACAACGTCGTCGGGGTGATCTACCTCAAGGACTCCCTGGAGGAG
GCCTACGCCCGTCTACAGGATCTGCGGGACATCCTGCTGGTCGCGACGCTGGTGGCCATGGCCTCGACGGTGGTGCTGGG
CGTGGCTCTGGCCCGCACGATCACGGGGCCGATCCGGGAGCTCACCCGCACCGCGGCGCTCATTGCCGGCGGCAACTTCG
ACCAGAAGATCCCCGTCCGGTCCGGCGATGAGATCGGCCAGCTGGCCGAGATGTTCAACCGGATGAGCCGGCAGCTGAAG
GAGACGATGAGCGAGATCCAGGACGAGAAGAGCCAGGCCGAAGCCATCCTGACCCACATGGCCGACGGCCTGATGGCGCT
CAACCGCGCCAGGCGCATCATCCGGCTCAACCCTGCTGCGCAGCGGATGTTCCAGATTCAGGAGCTGCAGGCGCTCGGCC
GCCGCCCCGGAGAGCTGGCTGAGGGTTCGGGGCTGGAGGAGGCCCTGGAGGAGGCGTGGGATCGGAACAGCGCCCTGACC
CGGCAGATCCGGCTGAAGGACCGGGTGCTGCAGGCCTACATCACCCCGCTGACCGGCGAGGGCCGTCACTCCGGCGGCAC
GGTCGTCGTCTTCCACGACATCACCGAGCTGGAGCGGCTGGAGAGCATGCGCCGGGAGTTCGTCGCCAACGTCTCGCACG
AGCTCAAGACGCCCCTCACGACGGTCAAGAGCTACGTGGAGACCCTGCTGGACGGCGCCGCCGACGATCCGGAGGTGCGT
GACCGTTTCCTGCGGGTGGTGGACGGGGAGACGGAGCGAATGGCCCGGCTGGTGCGGGATCTCCTGCGGCTGACCCAGAT
GGACGAGGGGACGCTCCGCTGGAACGTGAGGCCGCAAGACGTGGGCGAACTGGTGGCGGAAACGGTGGGGCGCCTGAGGG
TGCAGGCGGACCGGAAGCGGCTCACCGTCCTGTGCGAGGTGGACCCGGAGACGCCGCCCGCCCTCTGCGACTATGACAAG
ATCCAGCAGGTGGTGATCAACCTGCTGGCCAACGCCATCGAGTTCACGCCCAACGGCGGCCAGATCCGGGTGAGCGTGGC
GCCGGAGGGCGCGGATGCCGTGCGCGTCACCATCGCCGACACGGGGATCGGCATCCCGGCCCAGGACCTGCCCCGCATCT
TCGAGCGCTTCTACCGGGTGGACAAGGCCCGCTCCCGCTCGATGGGGGGCACCGGGCTGGGCCTCTCCATCGCCAAGCAG
ATCGTCGAGCTGTCGGGCGGCGCCATCGCCATCGCGTCCGAGGTGGACCGGGGGACCACGGTCACCTTCACGCTGCCTGC
GGCCCGGACTGCGGAGGTGAGACCGTCATGA

Upstream 100 bases:

>100_bases
GGCTCAGGGAGAAGCTGGAGGAGAACTCTGCCAGGCCGGAGTACATCAAGACGCGGCGGGGGGTCGGCTACTACTTCCAG
CGGTTCGACTGACGGAGAGG

Downstream 100 bases:

>100_bases
CGAAGCCTTCCGGCCGGGCGCGCGAGGTGCTGCTGGACCTCCTGCTGGCGGCGCTGGTGCTGACCAGCGTGGTGCTCACG
GTCCGCGTCTGGTATCCGGA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MDVVFRSIQGKLVVVYLLLIVVAMELASLYLMRELERSYIGKVQDDLHQSAQLLAGQLTNFFAGDRLDPEAVDQYMERWP
GEVLVLDANGVVIGATARLSNREELLGLKFSHDDVSPAFFGNTNRRIGKEGSQRMAYEAVPITVADNVVGVIYLKDSLEE
AYARLQDLRDILLVATLVAMASTVVLGVALARTITGPIRELTRTAALIAGGNFDQKIPVRSGDEIGQLAEMFNRMSRQLK
ETMSEIQDEKSQAEAILTHMADGLMALNRARRIIRLNPAAQRMFQIQELQALGRRPGELAEGSGLEEALEEAWDRNSALT
RQIRLKDRVLQAYITPLTGEGRHSGGTVVVFHDITELERLESMRREFVANVSHELKTPLTTVKSYVETLLDGAADDPEVR
DRFLRVVDGETERMARLVRDLLRLTQMDEGTLRWNVRPQDVGELVAETVGRLRVQADRKRLTVLCEVDPETPPALCDYDK
IQQVVINLLANAIEFTPNGGQIRVSVAPEGADAVRVTIADTGIGIPAQDLPRIFERFYRVDKARSRSMGGTGLGLSIAKQ
IVELSGGAIAIASEVDRGTTVTFTLPAARTAEVRPS

Sequences:

>Translated_596_residues
MDVVFRSIQGKLVVVYLLLIVVAMELASLYLMRELERSYIGKVQDDLHQSAQLLAGQLTNFFAGDRLDPEAVDQYMERWP
GEVLVLDANGVVIGATARLSNREELLGLKFSHDDVSPAFFGNTNRRIGKEGSQRMAYEAVPITVADNVVGVIYLKDSLEE
AYARLQDLRDILLVATLVAMASTVVLGVALARTITGPIRELTRTAALIAGGNFDQKIPVRSGDEIGQLAEMFNRMSRQLK
ETMSEIQDEKSQAEAILTHMADGLMALNRARRIIRLNPAAQRMFQIQELQALGRRPGELAEGSGLEEALEEAWDRNSALT
RQIRLKDRVLQAYITPLTGEGRHSGGTVVVFHDITELERLESMRREFVANVSHELKTPLTTVKSYVETLLDGAADDPEVR
DRFLRVVDGETERMARLVRDLLRLTQMDEGTLRWNVRPQDVGELVAETVGRLRVQADRKRLTVLCEVDPETPPALCDYDK
IQQVVINLLANAIEFTPNGGQIRVSVAPEGADAVRVTIADTGIGIPAQDLPRIFERFYRVDKARSRSMGGTGLGLSIAKQ
IVELSGGAIAIASEVDRGTTVTFTLPAARTAEVRPS
>Mature_596_residues
MDVVFRSIQGKLVVVYLLLIVVAMELASLYLMRELERSYIGKVQDDLHQSAQLLAGQLTNFFAGDRLDPEAVDQYMERWP
GEVLVLDANGVVIGATARLSNREELLGLKFSHDDVSPAFFGNTNRRIGKEGSQRMAYEAVPITVADNVVGVIYLKDSLEE
AYARLQDLRDILLVATLVAMASTVVLGVALARTITGPIRELTRTAALIAGGNFDQKIPVRSGDEIGQLAEMFNRMSRQLK
ETMSEIQDEKSQAEAILTHMADGLMALNRARRIIRLNPAAQRMFQIQELQALGRRPGELAEGSGLEEALEEAWDRNSALT
RQIRLKDRVLQAYITPLTGEGRHSGGTVVVFHDITELERLESMRREFVANVSHELKTPLTTVKSYVETLLDGAADDPEVR
DRFLRVVDGETERMARLVRDLLRLTQMDEGTLRWNVRPQDVGELVAETVGRLRVQADRKRLTVLCEVDPETPPALCDYDK
IQQVVINLLANAIEFTPNGGQIRVSVAPEGADAVRVTIADTGIGIPAQDLPRIFERFYRVDKARSRSMGGTGLGLSIAKQ
IVELSGGAIAIASEVDRGTTVTFTLPAARTAEVRPS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=36.734693877551, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=34.3220338983051, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788549, Length=409, Percent_Identity=25.6723716381418, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI145693157, Length=230, Percent_Identity=30.8695652173913, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI48994928, Length=404, Percent_Identity=24.7524752475248, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=32.8947368421053, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=33.2, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=29.6137339055794, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=27.1186440677966, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=289, Percent_Identity=30.7958477508651, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082128, Length=272, Percent_Identity=28.3088235294118, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=24.2553191489362, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=233, Percent_Identity=25.3218884120172, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=27.2340425531915, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789403, Length=202, Percent_Identity=29.2079207920792, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790300, Length=220, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=24.6636771300448, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65866; Mature: 65866

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVVFRSIQGKLVVVYLLLIVVAMELASLYLMRELERSYIGKVQDDLHQSAQLLAGQLTN
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAGDRLDPEAVDQYMERWPGEVLVLDANGVVIGATARLSNREELLGLKFSHDDVSPAFF
HHCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCHHHHEEEEECCCCCCCHHC
GNTNRRIGKEGSQRMAYEAVPITVADNVVGVIYLKDSLEEAYARLQDLRDILLVATLVAM
CCCCCCCCCCCCHHHHHEEEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ASTVVLGVALARTITGPIRELTRTAALIAGGNFDQKIPVRSGDEIGQLAEMFNRMSRQLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ETMSEIQDEKSQAEAILTHMADGLMALNRARRIIRLNPAAQRMFQIQELQALGRRPGELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHCCCCCCCC
EGSGLEEALEEAWDRNSALTRQIRLKDRVLQAYITPLTGEGRHSGGTVVVFHDITELERL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHH
ESMRREFVANVSHELKTPLTTVKSYVETLLDGAADDPEVRDRFLRVVDGETERMARLVRD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LLRLTQMDEGTLRWNVRPQDVGELVAETVGRLRVQADRKRLTVLCEVDPETPPALCDYDK
HHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHH
IQQVVINLLANAIEFTPNGGQIRVSVAPEGADAVRVTIADTGIGIPAQDLPRIFERFYRV
HHHHHHHHHHHHHEECCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
DKARSRSMGGTGLGLSIAKQIVELSGGAIAIASEVDRGTTVTFTLPAARTAEVRPS
HHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDVVFRSIQGKLVVVYLLLIVVAMELASLYLMRELERSYIGKVQDDLHQSAQLLAGQLTN
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFAGDRLDPEAVDQYMERWPGEVLVLDANGVVIGATARLSNREELLGLKFSHDDVSPAFF
HHCCCCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCHHHHEEEEECCCCCCCHHC
GNTNRRIGKEGSQRMAYEAVPITVADNVVGVIYLKDSLEEAYARLQDLRDILLVATLVAM
CCCCCCCCCCCCHHHHHEEEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ASTVVLGVALARTITGPIRELTRTAALIAGGNFDQKIPVRSGDEIGQLAEMFNRMSRQLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ETMSEIQDEKSQAEAILTHMADGLMALNRARRIIRLNPAAQRMFQIQELQALGRRPGELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHCCCCCCCC
EGSGLEEALEEAWDRNSALTRQIRLKDRVLQAYITPLTGEGRHSGGTVVVFHDITELERL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECHHHHHHH
ESMRREFVANVSHELKTPLTTVKSYVETLLDGAADDPEVRDRFLRVVDGETERMARLVRD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LLRLTQMDEGTLRWNVRPQDVGELVAETVGRLRVQADRKRLTVLCEVDPETPPALCDYDK
HHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHH
IQQVVINLLANAIEFTPNGGQIRVSVAPEGADAVRVTIADTGIGIPAQDLPRIFERFYRV
HHHHHHHHHHHHHEECCCCCEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHH
DKARSRSMGGTGLGLSIAKQIVELSGGAIAIASEVDRGTTVTFTLPAARTAEVRPS
HHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]