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The map label for this gene is resD [H]

Identifier: 51894424

GI number: 51894424

Start: 3514664

End: 3515362

Strand: Reverse

Name: resD [H]

Synonym: STH3290

Alternate gene names: 51894424

Gene position: 3515362-3514664 (Counterclockwise)

Preceding gene: 51894426

Following gene: 51894423

Centisome position: 98.58

GC content: 72.39

Gene sequence:

>699_bases
ATGGCCCCGGGGAAGCGGCCTGTGGTGCTGGTGGTGGACGACGAGCCCCGCATGCGCGAGCTGATCCGGCTGTACCTCGC
GGCGGAGTGCACCGTGCTCGAGGCCGGGGACGGCCTCACCGCCCTGCGGGCGGTGCGTGACGCGGGGCCTGACCTCGTGC
TGCTGGACGTGATGATGCCCCGGTTGGACGGGTGGCAGACGCTGCAACGCATCCGCGAGGAGTCTGCCGTGCCCGTCATC
ATGCTCACCGCCCGGGGCGGTGTGGCGGATCGGGTACAGGGGCTCCGGATGGGCGCCGACGACTACATCGCCAAGCCCTT
CGACGGCCGGGAGCTGGCCGCCCGGGTCCAGGCCGTGCTCCGCCGCTCGGCCGGACAGGTGGAGGCGAACGTCCCCATCC
GCCGGGGCAGCCTGACGATCCGGCCGGCAGAGCGGACGGCGTTGTACGCCGGCCGTCCCCTGCCCCTCACTCCCAAGGAG
TTTGACCTCCTGGCCCTGCTGGCGGCGCACCCGGGTCAGGTCTTCTCCCGGGAGAAGCTGCTGGACCGCATCTGGGGGCC
CGACTTCCAGGGCGACGCCCGCACGGTGGACGCCCACATCAAGAACCTGCGGGACAAGCTGGGCGAGGGCGCGGGGCTCA
TCCTCACGGTCTGGGGCGTGGGGTACCGGTTCGCGGAGGTGCCGGATGCGCAGCCTTAG

Upstream 100 bases:

>100_bases
CTGCCGGGGTTTGCTATACTGGTGACAAGTGCGGAAACGGACAAGCGCGGGGACGGGCCAGTCCGACCGGATCAGGGAGA
GGAATCGGAGGTGGTGGCCG

Downstream 100 bases:

>100_bases
TCTGGTCGCCCGGTTCTGGCTCTCCCTCTCCCTGCTCCTGCTCGTCGTGCTCGTCCCCATGGAGTACGCCCTGGACCAGC
TGCTGGAGCGCTTCTACGCC

Product: two-component response regulator, CheY-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAPGKRPVVLVVDDEPRMRELIRLYLAAECTVLEAGDGLTALRAVRDAGPDLVLLDVMMPRLDGWQTLQRIREESAVPVI
MLTARGGVADRVQGLRMGADDYIAKPFDGRELAARVQAVLRRSAGQVEANVPIRRGSLTIRPAERTALYAGRPLPLTPKE
FDLLALLAAHPGQVFSREKLLDRIWGPDFQGDARTVDAHIKNLRDKLGEGAGLILTVWGVGYRFAEVPDAQP

Sequences:

>Translated_232_residues
MAPGKRPVVLVVDDEPRMRELIRLYLAAECTVLEAGDGLTALRAVRDAGPDLVLLDVMMPRLDGWQTLQRIREESAVPVI
MLTARGGVADRVQGLRMGADDYIAKPFDGRELAARVQAVLRRSAGQVEANVPIRRGSLTIRPAERTALYAGRPLPLTPKE
FDLLALLAAHPGQVFSREKLLDRIWGPDFQGDARTVDAHIKNLRDKLGEGAGLILTVWGVGYRFAEVPDAQP
>Mature_231_residues
APGKRPVVLVVDDEPRMRELIRLYLAAECTVLEAGDGLTALRAVRDAGPDLVLLDVMMPRLDGWQTLQRIREESAVPVIM
LTARGGVADRVQGLRMGADDYIAKPFDGRELAARVQAVLRRSAGQVEANVPIRRGSLTIRPAERTALYAGRPLPLTPKEF
DLLALLAAHPGQVFSREKLLDRIWGPDFQGDARTVDAHIKNLRDKLGEGAGLILTVWGVGYRFAEVPDAQP

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=41.2556053811659, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=42.4107142857143, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=37.6623376623377, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789402, Length=184, Percent_Identity=42.9347826086957, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=37.8378378378378, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=42.4107142857143, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=35.5263157894737, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=40.1826484018265, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=34.5454545454545, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790860, Length=205, Percent_Identity=38.5365853658537, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=33.7662337662338, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790863, Length=240, Percent_Identity=30.8333333333333, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.4786324786325, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=38.8888888888889, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=34.1269841269841, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=137, Percent_Identity=33.5766423357664, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=34, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25459; Mature: 25328

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPGKRPVVLVVDDEPRMRELIRLYLAAECTVLEAGDGLTALRAVRDAGPDLVLLDVMMP
CCCCCCCEEEEECCCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCEEEEEHHHC
RLDGWQTLQRIREESAVPVIMLTARGGVADRVQGLRMGADDYIAKPFDGRELAARVQAVL
CCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHH
RRSAGQVEANVPIRRGSLTIRPAERTALYAGRPLPLTPKEFDLLALLAAHPGQVFSREKL
HHCCCCEEECCCEECCCEEEEECHHHEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
LDRIWGPDFQGDARTVDAHIKNLRDKLGEGAGLILTVWGVGYRFAEVPDAQP
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCC
>Mature Secondary Structure 
APGKRPVVLVVDDEPRMRELIRLYLAAECTVLEAGDGLTALRAVRDAGPDLVLLDVMMP
CCCCCCEEEEECCCHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCEEEEEHHHC
RLDGWQTLQRIREESAVPVIMLTARGGVADRVQGLRMGADDYIAKPFDGRELAARVQAVL
CCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHH
RRSAGQVEANVPIRRGSLTIRPAERTALYAGRPLPLTPKEFDLLALLAAHPGQVFSREKL
HHCCCCEEECCCEECCCEEEEECHHHEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
LDRIWGPDFQGDARTVDAHIKNLRDKLGEGAGLILTVWGVGYRFAEVPDAQP
HHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]