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The map label for this gene is baeS [H]

Identifier: 51894423

GI number: 51894423

Start: 3513331

End: 3514677

Strand: Reverse

Name: baeS [H]

Synonym: STH3289

Alternate gene names: 51894423

Gene position: 3514677-3513331 (Counterclockwise)

Preceding gene: 51894424

Following gene: 51894421

Centisome position: 98.56

GC content: 73.87

Gene sequence:

>1347_bases
ATGCGCAGCCTTAGTCTGGTCGCCCGGTTCTGGCTCTCCCTCTCCCTGCTCCTGCTCGTCGTGCTCGTCCCCATGGAGTA
CGCCCTGGACCAGCTGCTGGAGCGCTTCTACGCCACGCAGGTCACGGAGCCCCTCCTCTACCACGGCCGGCAACTCGCGG
ACATGCTGGCCGCAGAGGACGCGGCGCTGGCCGCCGCACCGCTCATGGCCGAGATGGTGGGGGGCGAGGTGGTGGTGCTG
GACCGGGAAGGAAGGCCGCGGTCCTTCCCGGGCGCCTCCGCGGTCGAGGTGCCCGAGGACATCCGGCGGGCGGTGGTCGT
CGGACGGACCCATGTGGACCAGCTGCGGACCCCGGAGGGAGCCACCTACATCGTCACCGGCGTGCCGGTCCAGGGGGGCG
AAGGAGGAGTGCTGCTGCTGGCGCCCGCCGATCCCCTCCGGCAGTCGTTCGACAGGGCCCGGCGCGGCCTGTGGCTGGCC
GGCGCCGCCGCGCTCCTGCTGGGCACGGGGCTCGCGCTGGTGATGGCCCGGAGCCTCACCCGCCCCGTGCTGGCGATGGA
ACGGGCGACCCGGGCCATCGCGCGCGGCGACTTCTCGGCGCGCGTGGCCCCGGCGGGCGCTAACGAGCTGGGCCGCCTCG
GCGAGGCGATCAACCGGATGGCGGAACAGCTGGAGGGCCACGAGCGCCGCCGGCGGGAGTTCCTGGCTGACGTGGCCCAC
GAGCTGCGCACGCCGCTGTCGTACATCCGCGGGTATACCCAGGCCCTGGCCGAGGGGGTCGTGACCGATCCTGCGGAGGT
CCGGCGATTCCAACGGGTGGTGATGGACGAGGTCGACCGGCTGAGCCGCCTCGTGGACGACCTGATGGACCTGGCGCAGA
TCGAAGAGGGGCAGATGGCCTTCGAGCGGGTGCCGCTGGATCTGCGCGTGCCGGTGGAGCAGGCGGTCCGGACCGTGCGG
TCGCAGGCGGAGGAGAAGGGCGTCGCCCTGGTGGTGGGCCTCCCGGACGCGCTGCCCCCCGTCCTCGCCGACGGCGGCCG
GATTCAGCAGGTGGTCTTCAACCTGCTGGACAACGCCCTGCGCCATACCCCGCCGGGAGGCGTGGTGCGGGTGTCCGCCG
CGGTCACGAGGGACGCCGTGGCGGTCCGGGTGCGGGACACGGGGGAGGGCATCGACCCGGCTCAGCTTCCCCACGTGTTC
GACCGCTTCCGCGGCCGGCGGAAGGGCGGCCGGGGGCTCGGTCTGGCGGTGGTGCGCTCCATCGTCCGGGCGCACGGCGG
TGACGTCGGCGTGGAGTCCCGTCCCGGCGGGGGCGCCGCCTTCTGGTTCTGGCTGCCGCGGGCCTGA

Upstream 100 bases:

>100_bases
GTGGACGCCCACATCAAGAACCTGCGGGACAAGCTGGGCGAGGGCGCGGGGCTCATCCTCACGGTCTGGGGCGTGGGGTA
CCGGTTCGCGGAGGTGCCGG

Downstream 100 bases:

>100_bases
GGGCAGGGCGCGGAGCGGCCAACGGAAAACGAGCACCCGGTCAGGGGTGCTCGTTCAGGTCTGCGGATCCGGGGACGCGC
GCTGGATCACTGGTCAGGCG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRSLSLVARFWLSLSLLLLVVLVPMEYALDQLLERFYATQVTEPLLYHGRQLADMLAAEDAALAAAPLMAEMVGGEVVVL
DREGRPRSFPGASAVEVPEDIRRAVVVGRTHVDQLRTPEGATYIVTGVPVQGGEGGVLLLAPADPLRQSFDRARRGLWLA
GAAALLLGTGLALVMARSLTRPVLAMERATRAIARGDFSARVAPAGANELGRLGEAINRMAEQLEGHERRRREFLADVAH
ELRTPLSYIRGYTQALAEGVVTDPAEVRRFQRVVMDEVDRLSRLVDDLMDLAQIEEGQMAFERVPLDLRVPVEQAVRTVR
SQAEEKGVALVVGLPDALPPVLADGGRIQQVVFNLLDNALRHTPPGGVVRVSAAVTRDAVAVRVRDTGEGIDPAQLPHVF
DRFRGRRKGGRGLGLAVVRSIVRAHGGDVGVESRPGGGAAFWFWLPRA

Sequences:

>Translated_448_residues
MRSLSLVARFWLSLSLLLLVVLVPMEYALDQLLERFYATQVTEPLLYHGRQLADMLAAEDAALAAAPLMAEMVGGEVVVL
DREGRPRSFPGASAVEVPEDIRRAVVVGRTHVDQLRTPEGATYIVTGVPVQGGEGGVLLLAPADPLRQSFDRARRGLWLA
GAAALLLGTGLALVMARSLTRPVLAMERATRAIARGDFSARVAPAGANELGRLGEAINRMAEQLEGHERRRREFLADVAH
ELRTPLSYIRGYTQALAEGVVTDPAEVRRFQRVVMDEVDRLSRLVDDLMDLAQIEEGQMAFERVPLDLRVPVEQAVRTVR
SQAEEKGVALVVGLPDALPPVLADGGRIQQVVFNLLDNALRHTPPGGVVRVSAAVTRDAVAVRVRDTGEGIDPAQLPHVF
DRFRGRRKGGRGLGLAVVRSIVRAHGGDVGVESRPGGGAAFWFWLPRA
>Mature_448_residues
MRSLSLVARFWLSLSLLLLVVLVPMEYALDQLLERFYATQVTEPLLYHGRQLADMLAAEDAALAAAPLMAEMVGGEVVVL
DREGRPRSFPGASAVEVPEDIRRAVVVGRTHVDQLRTPEGATYIVTGVPVQGGEGGVLLLAPADPLRQSFDRARRGLWLA
GAAALLLGTGLALVMARSLTRPVLAMERATRAIARGDFSARVAPAGANELGRLGEAINRMAEQLEGHERRRREFLADVAH
ELRTPLSYIRGYTQALAEGVVTDPAEVRRFQRVVMDEVDRLSRLVDDLMDLAQIEEGQMAFERVPLDLRVPVEQAVRTVR
SQAEEKGVALVVGLPDALPPVLADGGRIQQVVFNLLDNALRHTPPGGVVRVSAAVTRDAVAVRVRDTGEGIDPAQLPHVF
DRFRGRRKGGRGLGLAVVRSIVRAHGGDVGVESRPGGGAAFWFWLPRA

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=329, Percent_Identity=36.7781155015198, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789149, Length=343, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=35.7446808510638, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1786783, Length=274, Percent_Identity=33.9416058394161, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788549, Length=215, Percent_Identity=33.4883720930233, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87081816, Length=344, Percent_Identity=30.2325581395349, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=32.2709163346614, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=32, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786600, Length=285, Percent_Identity=30.5263157894737, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790861, Length=296, Percent_Identity=31.4189189189189, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790346, Length=292, Percent_Identity=28.7671232876712, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787894, Length=301, Percent_Identity=29.5681063122924, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=29.4871794871795, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=274, Percent_Identity=26.2773722627737, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=28.1938325991189, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789808, Length=290, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=226, Percent_Identity=30.0884955752212, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=306, Percent_Identity=26.797385620915, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=234, Percent_Identity=29.0598290598291, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790551, Length=282, Percent_Identity=26.5957446808511, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787374, Length=286, Percent_Identity=25.5244755244755, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790567, Length=134, Percent_Identity=32.089552238806, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48600; Mature: 48600

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLSLVARFWLSLSLLLLVVLVPMEYALDQLLERFYATQVTEPLLYHGRQLADMLAAED
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AALAAAPLMAEMVGGEVVVLDREGRPRSFPGASAVEVPEDIRRAVVVGRTHVDQLRTPEG
HHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCC
ATYIVTGVPVQGGEGGVLLLAPADPLRQSFDRARRGLWLAGAAALLLGTGLALVMARSLT
CEEEEEECEEECCCCCEEEEECCHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHH
RPVLAMERATRAIARGDFSARVAPAGANELGRLGEAINRMAEQLEGHERRRREFLADVAH
HHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRTPLSYIRGYTQALAEGVVTDPAEVRRFQRVVMDEVDRLSRLVDDLMDLAQIEEGQMA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
FERVPLDLRVPVEQAVRTVRSQAEEKGVALVVGLPDALPPVLADGGRIQQVVFNLLDNAL
HHHCCCCEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHH
RHTPPGGVVRVSAAVTRDAVAVRVRDTGEGIDPAQLPHVFDRFRGRRKGGRGLGLAVVRS
HCCCCCCEEEEEHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IVRAHGGDVGVESRPGGGAAFWFWLPRA
HHHHCCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MRSLSLVARFWLSLSLLLLVVLVPMEYALDQLLERFYATQVTEPLLYHGRQLADMLAAED
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AALAAAPLMAEMVGGEVVVLDREGRPRSFPGASAVEVPEDIRRAVVVGRTHVDQLRTPEG
HHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCC
ATYIVTGVPVQGGEGGVLLLAPADPLRQSFDRARRGLWLAGAAALLLGTGLALVMARSLT
CEEEEEECEEECCCCCEEEEECCHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHH
RPVLAMERATRAIARGDFSARVAPAGANELGRLGEAINRMAEQLEGHERRRREFLADVAH
HHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRTPLSYIRGYTQALAEGVVTDPAEVRRFQRVVMDEVDRLSRLVDDLMDLAQIEEGQMA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
FERVPLDLRVPVEQAVRTVRSQAEEKGVALVVGLPDALPPVLADGGRIQQVVFNLLDNAL
HHHCCCCEECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHH
RHTPPGGVVRVSAAVTRDAVAVRVRDTGEGIDPAQLPHVFDRFRGRRKGGRGLGLAVVRS
HCCCCCCEEEEEHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IVRAHGGDVGVESRPGGGAAFWFWLPRA
HHHHCCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]