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The map label for this gene is yvcQ [H]

Identifier: 51894348

GI number: 51894348

Start: 3427197

End: 3428312

Strand: Reverse

Name: yvcQ [H]

Synonym: STH3213

Alternate gene names: 51894348

Gene position: 3428312-3427197 (Counterclockwise)

Preceding gene: 51894349

Following gene: 51894347

Centisome position: 96.14

GC content: 69.44

Gene sequence:

>1116_bases
GTGCGCTTCTGGCAGTTTCTGTGGGACCGGATCAACTACATCGCCGTCTACGTGGCCTTCGCTGCGCTGTCCCTCGTGGT
GGTCCACCTGGACCTCATGCTCACCGGGGCGAGTCTGCAGGTGGTCAACCTCCTCTACATCTTCCTCCTGGGGCTGGTGG
GGCTCGTCGTCTACCTCTGGTGGGAATACCAGCGGATAGTCCCCTTCTACCGCCACCTGGCCGGGCTGACGGGTCGGGAG
CCCATCGCACAGCTGGCCCTACTGCCGGTGCCGCAGACGGCGGAGGGGGAGTTGCTGGCCGAGGCCTGGAGCCGCATGTA
CGGGCGGCTGAGCGGCGAGCTGGCGGCCGAGAGGGAGCGGGGGCAGCGGAACGTGAGCCTGGTCACCCAGTGGGCGCACC
ACATGAAGACCCCCGTCGCCGTCATCGACCTGCTGCTGCAGCGGGCCGACACGGAGGAGTGGCCGGAGGAGGCGCGGGCC
CTGGCAGCCGGCGTGGCCGAGGAGAATCAGCGGCTGCAGCACTCGCTGCAGATGCTGCTCAACACCGTCCGGCTGCAGGA
CTTCGCACAGGACTTCCGCGCGGAGCGGCTCGACCTGCTGGCGCTGGTCCGGGAGGTCATCAATGACGAGAAGCGGGCCT
TCATCGCGCGGCGGGTCTACCCTCAGGTGGTTGCGGAGGATGAGGGAGACCGGCCCTGGCTGGTGGAGAGCGACGCCAAG
TGGCTGCGCCTTGTGCTGGAGCAGGTGGTGAGCAACGCCCTGAAGTACGCCTCCCGGCCCCCGGAGGCGGACGAGCAGGG
GCGGGTGCTCTTCCGGCTGCGCCGGGAGGGTGGCGACGTGGTCCTGGAGATCGCCGACAACGGCGTCGGCATCCCGCCGG
AGGACCTGGGGCGCGTCTTCGACCCCTTCTTCACGGGGCTGAACGGCCGGGCCTTTCCGCAGGCGACCGGGATGGGGCTG
TACCTGGCCCGGGAGGTGTGCAGCCAACTGGGACACGGGATCAGCCTCGACTCGGCCCCGGGGGAGGGCACCACGGTACG
GCTGCGCTTCGCAGCGCCGCAGACCCTCTTCGCGGGGCTGCGGGACAGCCTTACAGCCAACGTGACGGAACCGTAA

Upstream 100 bases:

>100_bases
ACCCGGGTCCGGCGTCGGCTGGAGGAGCTGGGCCTTACCGGGGTGATCGAGACCAAGCGGGGCCAGGGCTATCGGCTGAA
CGCCGGCTGGGGGGAGTGAC

Downstream 100 bases:

>100_bases
GCTTCGTCCCGCGGCCTGCAAGCCAGATCGATGGGAACCGCCGGCCGGCGCCGCTACACTGGGAAGCGCAAGGCGCCGGC
CTCGCCGTTCATCGCCTGCG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRFWQFLWDRINYIAVYVAFAALSLVVVHLDLMLTGASLQVVNLLYIFLLGLVGLVVYLWWEYQRIVPFYRHLAGLTGRE
PIAQLALLPVPQTAEGELLAEAWSRMYGRLSGELAAERERGQRNVSLVTQWAHHMKTPVAVIDLLLQRADTEEWPEEARA
LAAGVAEENQRLQHSLQMLLNTVRLQDFAQDFRAERLDLLALVREVINDEKRAFIARRVYPQVVAEDEGDRPWLVESDAK
WLRLVLEQVVSNALKYASRPPEADEQGRVLFRLRREGGDVVLEIADNGVGIPPEDLGRVFDPFFTGLNGRAFPQATGMGL
YLAREVCSQLGHGISLDSAPGEGTTVRLRFAAPQTLFAGLRDSLTANVTEP

Sequences:

>Translated_371_residues
MRFWQFLWDRINYIAVYVAFAALSLVVVHLDLMLTGASLQVVNLLYIFLLGLVGLVVYLWWEYQRIVPFYRHLAGLTGRE
PIAQLALLPVPQTAEGELLAEAWSRMYGRLSGELAAERERGQRNVSLVTQWAHHMKTPVAVIDLLLQRADTEEWPEEARA
LAAGVAEENQRLQHSLQMLLNTVRLQDFAQDFRAERLDLLALVREVINDEKRAFIARRVYPQVVAEDEGDRPWLVESDAK
WLRLVLEQVVSNALKYASRPPEADEQGRVLFRLRREGGDVVLEIADNGVGIPPEDLGRVFDPFFTGLNGRAFPQATGMGL
YLAREVCSQLGHGISLDSAPGEGTTVRLRFAAPQTLFAGLRDSLTANVTEP
>Mature_371_residues
MRFWQFLWDRINYIAVYVAFAALSLVVVHLDLMLTGASLQVVNLLYIFLLGLVGLVVYLWWEYQRIVPFYRHLAGLTGRE
PIAQLALLPVPQTAEGELLAEAWSRMYGRLSGELAAERERGQRNVSLVTQWAHHMKTPVAVIDLLLQRADTEEWPEEARA
LAAGVAEENQRLQHSLQMLLNTVRLQDFAQDFRAERLDLLALVREVINDEKRAFIARRVYPQVVAEDEGDRPWLVESDAK
WLRLVLEQVVSNALKYASRPPEADEQGRVLFRLRREGGDVVLEIADNGVGIPPEDLGRVFDPFFTGLNGRAFPQATGMGL
YLAREVCSQLGHGISLDSAPGEGTTVRLRFAAPQTLFAGLRDSLTANVTEP

Specific function: Member of the two-component regulatory system yvcQ/yvcP. Probably activates yvcP by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=28.0769230769231, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994928, Length=125, Percent_Identity=32, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790861, Length=311, Percent_Identity=23.7942122186495, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41769; Mature: 41769

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFWQFLWDRINYIAVYVAFAALSLVVVHLDLMLTGASLQVVNLLYIFLLGLVGLVVYLW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WEYQRIVPFYRHLAGLTGREPIAQLALLPVPQTAEGELLAEAWSRMYGRLSGELAAERER
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GQRNVSLVTQWAHHMKTPVAVIDLLLQRADTEEWPEEARALAAGVAEENQRLQHSLQMLL
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTVRLQDFAQDFRAERLDLLALVREVINDEKRAFIARRVYPQVVAEDEGDRPWLVESDAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHH
WLRLVLEQVVSNALKYASRPPEADEQGRVLFRLRREGGDVVLEIADNGVGIPPEDLGRVF
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCEEEEECCCCCCCCHHHHHHHH
DPFFTGLNGRAFPQATGMGLYLAREVCSQLGHGISLDSAPGEGTTVRLRFAAPQTLFAGL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
RDSLTANVTEP
HHHCCCCCCCC
>Mature Secondary Structure
MRFWQFLWDRINYIAVYVAFAALSLVVVHLDLMLTGASLQVVNLLYIFLLGLVGLVVYLW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
WEYQRIVPFYRHLAGLTGREPIAQLALLPVPQTAEGELLAEAWSRMYGRLSGELAAERER
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GQRNVSLVTQWAHHMKTPVAVIDLLLQRADTEEWPEEARALAAGVAEENQRLQHSLQMLL
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTVRLQDFAQDFRAERLDLLALVREVINDEKRAFIARRVYPQVVAEDEGDRPWLVESDAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCHH
WLRLVLEQVVSNALKYASRPPEADEQGRVLFRLRREGGDVVLEIADNGVGIPPEDLGRVF
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCEEEEECCCCCCCCHHHHHHHH
DPFFTGLNGRAFPQATGMGLYLAREVCSQLGHGISLDSAPGEGTTVRLRFAAPQTLFAGL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
RDSLTANVTEP
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]