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The map label for this gene is etfA [H]

Identifier: 51894149

GI number: 51894149

Start: 3233361

End: 3234329

Strand: Reverse

Name: etfA [H]

Synonym: STH3013

Alternate gene names: 51894149

Gene position: 3234329-3233361 (Counterclockwise)

Preceding gene: 51894150

Following gene: 51894148

Centisome position: 90.7

GC content: 69.45

Gene sequence:

>969_bases
ATGGCACGCAACATCCTCGTGGTGGCTGAGGTTCGCAACGGGGCGATCCGTCCTGTGTCCTTCGAGTGCATCGCTGCCGG
CCGGGAGATCGCTGAGGGAGGCGCCATCACCGCGGTGCTGCTGGGGCAGCAGGGGGTCGACGCGTCCGAGCTGATCCGCC
GGGGCGCGGACCGGGTGGTGGTGGTCAAGGGCGACCATCTGGCCAACTACACGCCGGATGGCTGGCTGTCGGCGCTGCAG
CAGGTCTACCTGCAGGAGAAGCCCGACGTGGTCCTGATGGGCCACACGGGGATCGGCCGCGACCTCCTGCCCCGGTTCGC
CATGCGCAACGCGGCGGGCATGATCAGCGACGCCATCGCGGTGAAGGTCGAGGGCGGCCAGGTGGTCTTCACCCGGCCCA
TCTACGCCGGCAAGGCCTACGCGACCCAGGTGGTCAAGGACGGGCTGATCGTGGCCACGATCCGTCCCAACAACGTCGCA
GCCCTGGAAGCCGACCCCGGCCGCACAGGGGACGTCTCCGAGGCGGAGGCCGCTTCCGTGCATCTGCGCACGGTCGTCAA
GGAGGTCGTGCGGAAGGCCACGACCGGTGTGGACCTGACCGCCGCCAAGGTGGTCGTGGCCGGCGGGCGCGGCGTGCGGT
CCGCCGAGGGGTTCAAGCCGCTGTATGAGCTGGCCGAGGTGCTCGGGGGCGCCGTCGGCGCCAGCCGCGCTGCCGCCGAC
GCCGGGTACTGCGACTACGCCCTTCAGATCGGTCAGACGGGCAAGACCGTGACGCCCGACCTGTATATCGCCTGCGGCAT
CTCCGGGGCGATCCAGCACCTGGCGGGCATGAGCGCCTCGAAGGTGATCGTCGCCATCAACAAGGACCCCGATGCGCCGA
TCTTCAAGGTGGCCGACTACGGCATCGTCGGGGACCTGTTCGAGGTCGTGCCGCTCCTGACCAGGGAGTTCAAGGCGCTG
CTGGGGTAA

Upstream 100 bases:

>100_bases
TCAACAAGATGATCGCCGGCACGCCTGAGGAGCAGGCCCGGGAGCTGGTCCGCCTGCTCCGCAACGAAGCCAAGGTTGTA
TAGGGGAGGGCGCGAGAGCT

Downstream 100 bases:

>100_bases
GGACGGTCTGCCCCTGGGCAGCAGGGCACGGCGAAGCGGCGCCGACTTGGATCCTTGACCCATAGGTCCCCAACGGAACG
GTAAGGAGGGAGAGACTGTG

Product: electron transfer flavoprotein alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MARNILVVAEVRNGAIRPVSFECIAAGREIAEGGAITAVLLGQQGVDASELIRRGADRVVVVKGDHLANYTPDGWLSALQ
QVYLQEKPDVVLMGHTGIGRDLLPRFAMRNAAGMISDAIAVKVEGGQVVFTRPIYAGKAYATQVVKDGLIVATIRPNNVA
ALEADPGRTGDVSEAEAASVHLRTVVKEVVRKATTGVDLTAAKVVVAGGRGVRSAEGFKPLYELAEVLGGAVGASRAAAD
AGYCDYALQIGQTGKTVTPDLYIACGISGAIQHLAGMSASKVIVAINKDPDAPIFKVADYGIVGDLFEVVPLLTREFKAL
LG

Sequences:

>Translated_322_residues
MARNILVVAEVRNGAIRPVSFECIAAGREIAEGGAITAVLLGQQGVDASELIRRGADRVVVVKGDHLANYTPDGWLSALQ
QVYLQEKPDVVLMGHTGIGRDLLPRFAMRNAAGMISDAIAVKVEGGQVVFTRPIYAGKAYATQVVKDGLIVATIRPNNVA
ALEADPGRTGDVSEAEAASVHLRTVVKEVVRKATTGVDLTAAKVVVAGGRGVRSAEGFKPLYELAEVLGGAVGASRAAAD
AGYCDYALQIGQTGKTVTPDLYIACGISGAIQHLAGMSASKVIVAINKDPDAPIFKVADYGIVGDLFEVVPLLTREFKAL
LG
>Mature_321_residues
ARNILVVAEVRNGAIRPVSFECIAAGREIAEGGAITAVLLGQQGVDASELIRRGADRVVVVKGDHLANYTPDGWLSALQQ
VYLQEKPDVVLMGHTGIGRDLLPRFAMRNAAGMISDAIAVKVEGGQVVFTRPIYAGKAYATQVVKDGLIVATIRPNNVAA
LEADPGRTGDVSEAEAASVHLRTVVKEVVRKATTGVDLTAAKVVVAGGRGVRSAEGFKPLYELAEVLGGAVGASRAAADA
GYCDYALQIGQTGKTVTPDLYIACGISGAIQHLAGMSASKVIVAINKDPDAPIFKVADYGIVGDLFEVVPLLTREFKALL
G

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=321, Percent_Identity=41.1214953271028, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI189181759, Length=267, Percent_Identity=45.3183520599251, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1787990, Length=233, Percent_Identity=35.1931330472103, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1786226, Length=226, Percent_Identity=33.6283185840708, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082157, Length=256, Percent_Identity=29.296875, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17506929, Length=318, Percent_Identity=40.251572327044, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6325261, Length=297, Percent_Identity=37.037037037037, Blast_Score=170, Evalue=3e-43,
Organism=Drosophila melanogaster, GI17136898, Length=317, Percent_Identity=44.1640378548896, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24652801, Length=317, Percent_Identity=44.1640378548896, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33572; Mature: 33441

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNILVVAEVRNGAIRPVSFECIAAGREIAEGGAITAVLLGQQGVDASELIRRGADRVV
CCCCEEEEEEECCCCCCCEEHHHHHCCHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEE
VVKGDHLANYTPDGWLSALQQVYLQEKPDVVLMGHTGIGRDLLPRFAMRNAAGMISDAIA
EEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCEEE
VKVEGGQVVFTRPIYAGKAYATQVVKDGLIVATIRPNNVAALEADPGRTGDVSEAEAASV
EEEECCEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHH
HLRTVVKEVVRKATTGVDLTAAKVVVAGGRGVRSAEGFKPLYELAEVLGGAVGASRAAAD
HHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCC
AGYCDYALQIGQTGKTVTPDLYIACGISGAIQHLAGMSASKVIVAINKDPDAPIFKVADY
CCCCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECC
GIVGDLFEVVPLLTREFKALLG
CHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARNILVVAEVRNGAIRPVSFECIAAGREIAEGGAITAVLLGQQGVDASELIRRGADRVV
CCCEEEEEEECCCCCCCEEHHHHHCCHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEE
VVKGDHLANYTPDGWLSALQQVYLQEKPDVVLMGHTGIGRDLLPRFAMRNAAGMISDAIA
EEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCEEE
VKVEGGQVVFTRPIYAGKAYATQVVKDGLIVATIRPNNVAALEADPGRTGDVSEAEAASV
EEEECCEEEEECCCCCCHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHH
HLRTVVKEVVRKATTGVDLTAAKVVVAGGRGVRSAEGFKPLYELAEVLGGAVGASRAAAD
HHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCC
AGYCDYALQIGQTGKTVTPDLYIACGISGAIQHLAGMSASKVIVAINKDPDAPIFKVADY
CCCCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECC
GIVGDLFEVVPLLTREFKALLG
CHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]