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The map label for this gene is moaC [H]

Identifier: 51894039

GI number: 51894039

Start: 3127659

End: 3128243

Strand: Reverse

Name: moaC [H]

Synonym: STH2903

Alternate gene names: 51894039

Gene position: 3128243-3127659 (Counterclockwise)

Preceding gene: 51894040

Following gene: 51894038

Centisome position: 87.72

GC content: 70.6

Gene sequence:

>585_bases
ATGAGCAACATCAACCACGCAGATGCGCCGCGGCATGGGACGGACGAGCGCGGGGACAACGCGCAGCTCGCCGGCCAGAC
CGAGGGCGGCGGTGAGGCGCGGCTGACCCACCTGGACGAGCGCGGCCATGCCCGCATGGTCGACGTGGGTCCGAAGCCCG
AGACCGAGCGGGTGGCCGTCGCCCGGGCTGAGGTGCGGATGAAGCCGGAGACGCTGACCCTGATTCAGTCGGGCGGGGTG
CCGAAAGGCGACGTGCTGGGTGTGGCCCGGGTGGCGGGCATCATGGCCGCCAAGCGCACCGGCGATCTGATCCCCCTCTG
CCATCCGCTGCCCATCACGCAGGCCAGCGTCGACTTCGCCTTCGACGAAGCCGGCAGCCGGGTGCTGATCGAGGCCCGGG
TCTCCACCGTCGGCCGGACCGGCGTGGAGATGGAGGCGCTCACCGCCTGCGCCGCGGCCGCGCTGACCATCTACGATATG
GCCAAGGCCGTGGACAAGGGCATGGTCATCGGCGAGGTGCGGCTGGTGAAGAAGACCGGCGGCAAGAGCGGGACCTATAT
CCGCCCCGGTGAGGACGTGGAGTGA

Upstream 100 bases:

>100_bases
CCTGCGCAAGCCCCGGGAGCACAACTTCGACGACGCCGAGTCGGACTACGTCCTGCGGGTCATGCACGGCATCGGCGGGT
AGCCGCGAAAGGGGTGCGAC

Downstream 100 bases:

>100_bases
CCCACGACGCGCATATGTCAAGAGGCCCCCGTGCCGGCGGCGCGGGGGCTTTGCGCTGGCCGCGAACGGGCCCTTCTTCC
CCTCTATCTGAGTGAGAACA

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSNINHADAPRHGTDERGDNAQLAGQTEGGGEARLTHLDERGHARMVDVGPKPETERVAVARAEVRMKPETLTLIQSGGV
PKGDVLGVARVAGIMAAKRTGDLIPLCHPLPITQASVDFAFDEAGSRVLIEARVSTVGRTGVEMEALTACAAAALTIYDM
AKAVDKGMVIGEVRLVKKTGGKSGTYIRPGEDVE

Sequences:

>Translated_194_residues
MSNINHADAPRHGTDERGDNAQLAGQTEGGGEARLTHLDERGHARMVDVGPKPETERVAVARAEVRMKPETLTLIQSGGV
PKGDVLGVARVAGIMAAKRTGDLIPLCHPLPITQASVDFAFDEAGSRVLIEARVSTVGRTGVEMEALTACAAAALTIYDM
AKAVDKGMVIGEVRLVKKTGGKSGTYIRPGEDVE
>Mature_193_residues
SNINHADAPRHGTDERGDNAQLAGQTEGGGEARLTHLDERGHARMVDVGPKPETERVAVARAEVRMKPETLTLIQSGGVP
KGDVLGVARVAGIMAAKRTGDLIPLCHPLPITQASVDFAFDEAGSRVLIEARVSTVGRTGVEMEALTACAAAALTIYDMA
KAVDKGMVIGEVRLVKKTGGKSGTYIRPGEDVE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=160, Percent_Identity=55, Blast_Score=163, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI32566331, Length=158, Percent_Identity=43.0379746835443, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574490, Length=157, Percent_Identity=49.6815286624204, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=51.8248175182482, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 20393; Mature: 20261

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNINHADAPRHGTDERGDNAQLAGQTEGGGEARLTHLDERGHARMVDVGPKPETERVAV
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCEEE
ARAEVRMKPETLTLIQSGGVPKGDVLGVARVAGIMAAKRTGDLIPLCHPLPITQASVDFA
EEEHEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
FDEAGSRVLIEARVSTVGRTGVEMEALTACAAAALTIYDMAKAVDKGMVIGEVRLVKKTG
ECCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC
GKSGTYIRPGEDVE
CCCCCEECCCCCCC
>Mature Secondary Structure 
SNINHADAPRHGTDERGDNAQLAGQTEGGGEARLTHLDERGHARMVDVGPKPETERVAV
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCEEE
ARAEVRMKPETLTLIQSGGVPKGDVLGVARVAGIMAAKRTGDLIPLCHPLPITQASVDFA
EEEHEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
FDEAGSRVLIEARVSTVGRTGVEMEALTACAAAALTIYDMAKAVDKGMVIGEVRLVKKTG
ECCCCCEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECC
GKSGTYIRPGEDVE
CCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA