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The map label for this gene is groES

Identifier: 51894034

GI number: 51894034

Start: 3122188

End: 3122481

Strand: Reverse

Name: groES

Synonym: STH2898

Alternate gene names: 51894034

Gene position: 3122481-3122188 (Counterclockwise)

Preceding gene: 51894036

Following gene: 51894033

Centisome position: 87.56

GC content: 62.59

Gene sequence:

>294_bases
ATGAACGTCAAGCCGTTGGGCGCTCGGGTCGTCATCAAGCCGCTTGAGAAGGAAGAGCGCACCAAGAGCGGCATTGTGCT
GCCCGACACTGCGAAGGAGAAGCCCCAGCAGGGTAAGGTCATCGCCGTGGGCCCCGGCCGTACCCTGGAGTCCGGGACGA
AGGTGGAGCTCGAGGTCAAGGAGGGCGACACCGTCATCTTCTCCAAGTACGCGGGCACCGAGGTCAAGATCGACGGCGAG
GAGTACATCATCCTGGACGGCGAGCGGGACATTCTCGCCATCGTTCAGGGTTAG

Upstream 100 bases:

>100_bases
GACTTGACTGCCTCCAGTTCCTTTTCTATCATAGGTCATGGTGTTAGCACTCGGGCGGAATGAGTGCTAACAGACTCAGC
ACTGAGGAGGGACCTTCGAG

Downstream 100 bases:

>100_bases
AGGGAGGTCTTCCATAGATGACTGCGAAGCAGATTATCTTTGATGAGGCCGCCCGGCGCAAGCTGCAGGCCGGTGTGGAC
GCTCTTGCCAATACCGTGAA

Product: 10 kDa chaperonin

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MNVKPLGARVVIKPLEKEERTKSGIVLPDTAKEKPQQGKVIAVGPGRTLESGTKVELEVKEGDTVIFSKYAGTEVKIDGE
EYIILDGERDILAIVQG

Sequences:

>Translated_97_residues
MNVKPLGARVVIKPLEKEERTKSGIVLPDTAKEKPQQGKVIAVGPGRTLESGTKVELEVKEGDTVIFSKYAGTEVKIDGE
EYIILDGERDILAIVQG
>Mature_97_residues
MNVKPLGARVVIKPLEKEERTKSGIVLPDTAKEKPQQGKVIAVGPGRTLESGTKVELEVKEGDTVIFSKYAGTEVKIDGE
EYIILDGERDILAIVQG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=98, Percent_Identity=47.9591836734694, Blast_Score=77, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=36.9565217391304, Blast_Score=66, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356029, Length=91, Percent_Identity=41.7582417582418, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358317, Length=92, Percent_Identity=41.304347826087, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_SYMTH (Q67KB7)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076725.1
- ProteinModelPortal:   Q67KB7
- SMR:   Q67KB7
- GeneID:   2980026
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2898
- NMPDR:   fig|292459.1.peg.2772
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- BioCyc:   STHE292459:STH2898-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10518; Mature: 10518

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKPLGARVVIKPLEKEERTKSGIVLPDTAKEKPQQGKVIAVGPGRTLESGTKVELEVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
EGDTVIFSKYAGTEVKIDGEEYIILDGERDILAIVQG
CCCEEEEEECCCCEEEECCCEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MNVKPLGARVVIKPLEKEERTKSGIVLPDTAKEKPQQGKVIAVGPGRTLESGTKVELEVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
EGDTVIFSKYAGTEVKIDGEEYIILDGERDILAIVQG
CCCEEEEEECCCCEEEECCCEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA