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The map label for this gene is argJ

Identifier: 51894026

GI number: 51894026

Start: 3113949

End: 3115157

Strand: Reverse

Name: argJ

Synonym: STH2890

Alternate gene names: 51894026

Gene position: 3115157-3113949 (Counterclockwise)

Preceding gene: 51894027

Following gene: 51894020

Centisome position: 87.35

GC content: 73.04

Gene sequence:

>1209_bases
ATGGAGTGGCTGGCAGGCGGCGTGACGGCGCCGGCGGGTTTCGTGGCCGCGGGCGCGTGCGCGGACATCAAGGGGAACGG
CGCGGGGAAGAAGGACGTGGCCCTGCTCGCCTCCCGGGTTCCCTGCGCGGCCGCGGGGGTGTACACCACCAACCTGGTGA
AGGCGGCGCCGGTGGTGCTCACCCGGGGGCGGACCGAGACCGGTGAGCTGCAGGCCGTGGTGGCCAACTCCGGCAACGCC
AACGCCTGCACCGGCGAGCAGGGGATGCGGGACGCGGCCGAGATGGCCCGGCTGGCCGCGGAGGCCCTGGGCATCCGGCC
CGAGCTGATGGGTGTGGCTTCGACGGGCGTGATCGGCGTACCGCTGCCGATGGACCGGGTGTCGGCGGGCATCAGGGCCG
CGGCCGCGGCGCTCTCCCCGGAGGGCGGCGCCGACGCGGCGGAGGCCATCATGACCACCGACACCTTCCCGAAGCAGGCG
GCGGCGCGGCTGGAGATCGGCGGGGCGACGGTCACCATCGGGGCGATGGCCAAGGGCTCCGGCATGATCCACCCCAACAT
GGCGACGATGCTGGGGTTCGTCACCACCGACGCCGCCGTGGACGCGGCCGCCCTGCGGGAGGCCCTCCGGGAGGCCACGG
ACCGTTCCTTCAACATGATCACGGTGGACGGCGACACCTCGACCAACGACATGGTCCTCGTCCTGGCCAACGGCCTCGCG
GGCAACCCCAGGATCATGCCGGGCTCCGCCCACTACCGGGCGTTCGCCGACGCGCTGGCGGCGGTGCTCATCCACCTGGC
GAAGGAGATCGCCCGGGACGGCGAGGGCGCGACCAAGCTGATCGAGGTGCGGGTGAAGGGGGCCGCGACCCTCTCCGACG
CCCGCAAGGCGGCCCGGGCGGTCTGCGGGTCGAACCTGGTGAAGGCCGCGGTCTTCGGCGAGGACGCCAACTGGGGCCGC
GTGCTGGCGGCCCTGGGCTATTCGGGGGCGCAGTTCGACCCCGGCCGGGTGGACCTGTGGCTGGGCGACCTGCAGATGAT
GCGCGCCGGCGAGCCGGTGGCCTTTGACGAGGCGGCCGCGGCCCGGGTACTGCGGGAGAAGGAGGTCGTCTTCACCGCCG
ACCTGCACGCCGGCGAATGCGAGGCCACCGCCTGGGGCTGCGACCTGACGTATGACTACGTGAAGATCAACGGCAGTTAC
CGGACCTAG

Upstream 100 bases:

>100_bases
CGATGATGCGGCTGCTGGTGCCGCCGGAGGAGTTGGACGACGAGCCCTGGGAGATCCCCCTGGTGGCCCGTCCGAACTGG
GTAAAGGGGTAGATGAGCAC

Downstream 100 bases:

>100_bases
CAGGCTGTGTCCGAGAACGACGGCGGGCGCAGGACACGGAGCGCCCGCGTCTCCGCTTTTTTCTGGTCGTGCCGGCTCGA
CTACCGGACGTCGTACTTGC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MEWLAGGVTAPAGFVAAGACADIKGNGAGKKDVALLASRVPCAAAGVYTTNLVKAAPVVLTRGRTETGELQAVVANSGNA
NACTGEQGMRDAAEMARLAAEALGIRPELMGVASTGVIGVPLPMDRVSAGIRAAAAALSPEGGADAAEAIMTTDTFPKQA
AARLEIGGATVTIGAMAKGSGMIHPNMATMLGFVTTDAAVDAAALREALREATDRSFNMITVDGDTSTNDMVLVLANGLA
GNPRIMPGSAHYRAFADALAAVLIHLAKEIARDGEGATKLIEVRVKGAATLSDARKAARAVCGSNLVKAAVFGEDANWGR
VLAALGYSGAQFDPGRVDLWLGDLQMMRAGEPVAFDEAAAARVLREKEVVFTADLHAGECEATAWGCDLTYDYVKINGSY
RT

Sequences:

>Translated_402_residues
MEWLAGGVTAPAGFVAAGACADIKGNGAGKKDVALLASRVPCAAAGVYTTNLVKAAPVVLTRGRTETGELQAVVANSGNA
NACTGEQGMRDAAEMARLAAEALGIRPELMGVASTGVIGVPLPMDRVSAGIRAAAAALSPEGGADAAEAIMTTDTFPKQA
AARLEIGGATVTIGAMAKGSGMIHPNMATMLGFVTTDAAVDAAALREALREATDRSFNMITVDGDTSTNDMVLVLANGLA
GNPRIMPGSAHYRAFADALAAVLIHLAKEIARDGEGATKLIEVRVKGAATLSDARKAARAVCGSNLVKAAVFGEDANWGR
VLAALGYSGAQFDPGRVDLWLGDLQMMRAGEPVAFDEAAAARVLREKEVVFTADLHAGECEATAWGCDLTYDYVKINGSY
RT
>Mature_402_residues
MEWLAGGVTAPAGFVAAGACADIKGNGAGKKDVALLASRVPCAAAGVYTTNLVKAAPVVLTRGRTETGELQAVVANSGNA
NACTGEQGMRDAAEMARLAAEALGIRPELMGVASTGVIGVPLPMDRVSAGIRAAAAALSPEGGADAAEAIMTTDTFPKQA
AARLEIGGATVTIGAMAKGSGMIHPNMATMLGFVTTDAAVDAAALREALREATDRSFNMITVDGDTSTNDMVLVLANGLA
GNPRIMPGSAHYRAFADALAAVLIHLAKEIARDGEGATKLIEVRVKGAATLSDARKAARAVCGSNLVKAAVFGEDANWGR
VLAALGYSGAQFDPGRVDLWLGDLQMMRAGEPVAFDEAAAARVLREKEVVFTADLHAGECEATAWGCDLTYDYVKINGSY
RT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=416, Percent_Identity=38.7019230769231, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_SYMTH (Q67KC5)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076717.1
- ProteinModelPortal:   Q67KC5
- SMR:   Q67KC5
- MEROPS:   T05.001
- GeneID:   2982163
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2890
- NMPDR:   fig|292459.1.peg.2765
- HOGENOM:   HBG284202
- OMA:   VHENSAY
- ProtClustDB:   PRK05388
- BioCyc:   STHE292459:STH2890-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 41138; Mature: 41138

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLAGGVTAPAGFVAAGACADIKGNGAGKKDVALLASRVPCAAAGVYTTNLVKAAPVVL
CCCCCCCCCCCCHHHCCCCEECCCCCCCCCHHHHHHHHCCCCHHCCHHHHHHHHHCCEEE
TRGRTETGELQAVVANSGNANACTGEQGMRDAAEMARLAAEALGIRPELMGVASTGVIGV
ECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEECCCEEEC
PLPMDRVSAGIRAAAAALSPEGGADAAEAIMTTDTFPKQAAARLEIGGATVTIGAMAKGS
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHEEEECCCEEEEEEEECCC
GMIHPNMATMLGFVTTDAAVDAAALREALREATDRSFNMITVDGDTSTNDMVLVLANGLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCC
GNPRIMPGSAHYRAFADALAAVLIHLAKEIARDGEGATKLIEVRVKGAATLSDARKAARA
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
VCGSNLVKAAVFGEDANWGRVLAALGYSGAQFDPGRVDLWLGDLQMMRAGEPVAFDEAAA
HHCCHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCHHHH
ARVLREKEVVFTADLHAGECEATAWGCDLTYDYVKINGSYRT
HHHHHHCCEEEEECCCCCCCCCEEECCCEEEEEEEECCCCCC
>Mature Secondary Structure
MEWLAGGVTAPAGFVAAGACADIKGNGAGKKDVALLASRVPCAAAGVYTTNLVKAAPVVL
CCCCCCCCCCCCHHHCCCCEECCCCCCCCCHHHHHHHHCCCCHHCCHHHHHHHHHCCEEE
TRGRTETGELQAVVANSGNANACTGEQGMRDAAEMARLAAEALGIRPELMGVASTGVIGV
ECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHEEECCCEEEC
PLPMDRVSAGIRAAAAALSPEGGADAAEAIMTTDTFPKQAAARLEIGGATVTIGAMAKGS
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHEEEECCCEEEEEEEECCC
GMIHPNMATMLGFVTTDAAVDAAALREALREATDRSFNMITVDGDTSTNDMVLVLANGLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCC
GNPRIMPGSAHYRAFADALAAVLIHLAKEIARDGEGATKLIEVRVKGAATLSDARKAARA
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHH
VCGSNLVKAAVFGEDANWGRVLAALGYSGAQFDPGRVDLWLGDLQMMRAGEPVAFDEAAA
HHCCHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCHHHH
ARVLREKEVVFTADLHAGECEATAWGCDLTYDYVKINGSYRT
HHHHHHCCEEEEECCCCCCCCCEEECCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA