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The map label for this gene is grdB [H]

Identifier: 51894004

GI number: 51894004

Start: 3091230

End: 3092519

Strand: Reverse

Name: grdB [H]

Synonym: STH2867

Alternate gene names: 51894004

Gene position: 3092519-3091230 (Counterclockwise)

Preceding gene: 51894005

Following gene: 51894003

Centisome position: 86.72

GC content: 69.46

Gene sequence:

>1290_bases
GTGCGGATTGTGCATTACCTGAACCAGTTCTTCGGTGGAATCGGAGGTGAGGAGCACGCCGGCGTGCGGCCCGAGGTACG
CCCCGGCCCGGTGGGGCCCGGGATGGCCTTGAAGGCGGCCCTGGGCGACGCCGGGGAGATCGTGGCCACCGTGATCTGCG
GCGACTCCTGGTTCAACGAGAACCTGGAGGAAGCCAAGGCCACCGTGCTCGCGCTGATCCGGCAGCAGAACCCCGACCTG
GTCGTCGCCGGCCCGGCCTTCAACGCCGGCCGCTACGGCATGGCGTGCGGGGCGGTGGCCGAGGTGGTCAGCAAGGAGCT
CGGGATCCCCGTCGTGACCGGCATGTTCCTGGAGAATCCCGGCGTGGAGGTCTACCGCCGGTACGCATGGGTGGTGGAGA
CCGGCAACTCCGCCGCCTCCATGCGGACGGCCATCCCGGCCATGGCGGCCCTGATCCGGCGGCTGGCGGCGGGGCAGGAG
CCCGAACCGGGCACCTATCTGGAACGGGGCCTGCGGGTCAACACCTTCGCGGCGGAGCGGGGCTCCGCCCGGGCGGTGGA
GATGCTGGTGCGCAAGCTGAAAGGCGAGCCCTACACCACCGAGTACCCCATGCCCTCCTTCGACCGGGTGCCGCCCAACC
CGCCGGTGAAGGACCTGAGCAAGGCGAAGATCGCCCTGGTCACCTCCGGCGGCATCGTGCCCAAGGGCAACCCGGACCAC
ATCGAATCCTCCTCAGCATCCAAGTACGGCAAGTACTACCTGGGTGACCTCGACGACCTGACCGCCGAGACGCACCAGAC
CGCCCACGGCGGCTACGACCCGACCTACGCCAACGCCGACGCCGACCGGGTGCTCCCCGTGGACGTCATGCGGGAGCTGG
AGCGGGAAGGCGTCATCGGCAAGCTGCACGACTACTGGTACGCGACCGTGGGCAACGGCACCTCGGTGGCCAACGCCCGA
GCCTACGCCCGGGAGATCGCCGAGGACCTGAAGAAGTACGAGGTGGATGCCGTCATCCTCACCTCCACCTGAGGGACCTG
CACTCGTTGCGGAGCAACGATGGTGAAGGAGATCGAGCGGGCTGGCATCCCCGTGGTCCACGTCTGCACCGTGGTGCCGA
TCTCGCTGACCGTGGGCGCCAACCGGATCGTGCCGGCGGTGGCCATCCCCCATCCGCTGGGCAACCCGGCGCTGCCGCCC
GACGAGGAGCGGACCCTGCGCCGCCGGCTGGTGATGAAGGCGCTGCAGGCGCTGACCACCCCGGTGGACGGGCAGACGGT
GTTCGAGTAA

Upstream 100 bases:

>100_bases
CAGGTCTCCCTGATGGAGATGGTGCTGGACGTGGAGGCGATCGTCCAGGAGGTCCGCTCGATCCGCGAGAAGTACGCCGC
CTGGTAAAGGGGGGTCACAC

Downstream 100 bases:

>100_bases
GACCCGGAGGGGGCGCCGTGATTGCGGCGCCCCTTACGTGCCGCGGGGCGGCGTTCCGGGGTGCCCGGTTCGTAGCGGCG
TGCGCGGCGATGGACCGGTC

Product: glycine reductase complex selenoprotein B

Products: NA

Alternate protein names: Selenoprotein PB gamma [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRIVHYLNQFFGGIGGEEHAGVRPEVRPGPVGPGMALKAALGDAGEIVATVICGDSWFNENLEEAKATVLALIRQQNPDL
VVAGPAFNAGRYGMACGAVAEVVSKELGIPVVTGMFLENPGVEVYRRYAWVVETGNSAASMRTAIPAMAALIRRLAAGQE
PEPGTYLERGLRVNTFAAERGSARAVEMLVRKLKGEPYTTEYPMPSFDRVPPNPPVKDLSKAKIALVTSGGIVPKGNPDH
IESSSASKYGKYYLGDLDDLTAETHQTAHGGYDPTYANADADRVLPVDVMRELEREGVIGKLHDYWYATVGNGTSVANAR
AYAREIAEDLKKYEVDAVILTSTUGTCTRCGATMVKEIERAGIPVVHVCTVVPISLTVGANRIVPAVAIPHPLGNPALPP
DEERTLRRRLVMKALQALTTPVDGQTVFE

Sequences:

>Translated_429_residues
MRIVHYLNQFFGGIGGEEHAGVRPEVRPGPVGPGMALKAALGDAGEIVATVICGDSWFNENLEEAKATVLALIRQQNPDL
VVAGPAFNAGRYGMACGAVAEVVSKELGIPVVTGMFLENPGVEVYRRYAWVVETGNSAASMRTAIPAMAALIRRLAAGQE
PEPGTYLERGLRVNTFAAERGSARAVEMLVRKLKGEPYTTEYPMPSFDRVPPNPPVKDLSKAKIALVTSGGIVPKGNPDH
IESSSASKYGKYYLGDLDDLTAETHQTAHGGYDPTYANADADRVLPVDVMRELEREGVIGKLHDYWYATVGNGTSVANAR
AYAREIAEDLKKYEVDAVILTST*GTCTRCGATMVKEIERAGIPVVHVCTVVPISLTVGANRIVPAVAIPHPLGNPALPP
DEERTLRRRLVMKALQALTTPVDGQTVFE
>Mature_429_residues
MRIVHYLNQFFGGIGGEEHAGVRPEVRPGPVGPGMALKAALGDAGEIVATVICGDSWFNENLEEAKATVLALIRQQNPDL
VVAGPAFNAGRYGMACGAVAEVVSKELGIPVVTGMFLENPGVEVYRRYAWVVETGNSAASMRTAIPAMAALIRRLAAGQE
PEPGTYLERGLRVNTFAAERGSARAVEMLVRKLKGEPYTTEYPMPSFDRVPPNPPVKDLSKAKIALVTSGGIVPKGNPDH
IESSSASKYGKYYLGDLDDLTAETHQTAHGGYDPTYANADADRVLPVDVMRELEREGVIGKLHDYWYATVGNGTSVANAR
AYAREIAEDLKKYEVDAVILTST*GTCTRCGATMVKEIERAGIPVVHVCTVVPISLTVGANRIVPAVAIPHPLGNPALPP
DEERTLRRRLVMKALQALTTPVDGQTVFE

Specific function: In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated seleno

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdB/grdF/grdH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010186
- InterPro:   IPR022787
- InterPro:   IPR010187 [H]

Pfam domain/function: PF07355 GRDB [H]

EC number: =1.21.4.2 [H]

Molecular weight: Translated: 45882; Mature: 45882

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVHYLNQFFGGIGGEEHAGVRPEVRPGPVGPGMALKAALGDAGEIVATVICGDSWFNE
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHCC
NLEEAKATVLALIRQQNPDLVVAGPAFNAGRYGMACGAVAEVVSKELGIPVVTGMFLENP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHEECCC
GVEVYRRYAWVVETGNSAASMRTAIPAMAALIRRLAAGQEPEPGTYLERGLRVNTFAAER
CHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCEEEEECCCC
GSARAVEMLVRKLKGEPYTTEYPMPSFDRVPPNPPVKDLSKAKIALVTSGGIVPKGNPDH
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCC
IESSSASKYGKYYLGDLDDLTAETHQTAHGGYDPTYANADADRVLPVDVMRELEREGVIG
CCCCCHHHCCCEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEE
KLHDYWYATVGNGTSVANARAYAREIAEDLKKYEVDAVILTSTGTCTRCGATMVKEIERA
EECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHC
GIPVVHVCTVVPISLTVGANRIVPAVAIPHPLGNPALPPDEERTLRRRLVMKALQALTTP
CCCEEEEEHHEEEEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
VDGQTVFE
CCCCCCCC
>Mature Secondary Structure
MRIVHYLNQFFGGIGGEEHAGVRPEVRPGPVGPGMALKAALGDAGEIVATVICGDSWFNE
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCHHHCC
NLEEAKATVLALIRQQNPDLVVAGPAFNAGRYGMACGAVAEVVSKELGIPVVTGMFLENP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHEECCC
GVEVYRRYAWVVETGNSAASMRTAIPAMAALIRRLAAGQEPEPGTYLERGLRVNTFAAER
CHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCEEEEECCCC
GSARAVEMLVRKLKGEPYTTEYPMPSFDRVPPNPPVKDLSKAKIALVTSGGIVPKGNPDH
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCC
IESSSASKYGKYYLGDLDDLTAETHQTAHGGYDPTYANADADRVLPVDVMRELEREGVIG
CCCCCHHHCCCEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEE
KLHDYWYATVGNGTSVANARAYAREIAEDLKKYEVDAVILTSTGTCTRCGATMVKEIERA
EECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHC
GIPVVHVCTVVPISLTVGANRIVPAVAIPHPLGNPALPPDEERTLRRRLVMKALQALTTP
CCCEEEEEHHEEEEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
VDGQTVFE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA