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The map label for this gene is yfnC [H]

Identifier: 51893733

GI number: 51893733

Start: 2784420

End: 2785601

Strand: Reverse

Name: yfnC [H]

Synonym: STH2595

Alternate gene names: 51893733

Gene position: 2785601-2784420 (Counterclockwise)

Preceding gene: 51893735

Following gene: 51893732

Centisome position: 78.11

GC content: 72.08

Gene sequence:

>1182_bases
TTGAACTCCACCGTGTCGGCGGGGCGCCCGGTCCTCGCCCTCCTGCTGGTGCTCAGCCTGACCCACGCCGTCATTGACCT
GACCTCCGGCGCGATCGTCGCGCTCCTGCCGGCCATGCGGGAGGCCTACTCGCTCTCCTACGCCATGGTCGGCCTCATCC
CGCTGTTTGCCAACCTGACGTCCACGTTCACCCAGCCCGTCTTCGGCATCATCTCCGACCGGTCGGAGATGCGCTGGCTC
CTGCCGCTCAGCGTGGCCCTGGGCGGGCTCGGCCTCGCGGCGGTGGGGTACGTCAGCAACTACTGGCTGGTCCTGGCCGC
GGTGGTGATCAGCGCGCTGGGCAGCGCGGCCTTCCACCCCGAGGGCGCGCACGCCGCCCACAACCTGGCCGGGGAGCGCC
GTGCCCTGGCGATGGCGATCTACAGCGTCGGCGGCAACCTGGGGTACGCGCTGGGGCCGGGCTTCGCCGCGGCCCTGATC
GCCGCCTTCGGCCTGCGGGGGACGGGGCTCGCGGCGCTGCTGCCGCTCGCGCTCGCCGCCTTCCTGATATGGCTCCTGCC
CCGCTGGCGGGCCCACGAGCAGGAGGCGGCGGCCCGGAAGCGGGAGCAGGCGGAGCCCGGCGAGACCAACTGGCGGGGCA
CGGTCCTGATCACGCTGGTGGTGATCCTGCGCTCCATCATCCACCTGGGCATGACGACGTACGTCCCGTTCTTCTGGATC
GACGTGCTCGGCAACGCCCCGGCCACCGCCGGCCTGGTGCAGACGACCTACCTGCTCGCCGGGGTGCTCGGGACGCTGCT
GGGCGCGCCGCTGGCGGACCGGTTCGGCACCAAGCCTGTGCTCATCGCCTCCTTCGCCCTGCTGCTGCCGGTGCAGGCCG
TGCTCGCCTCCCTGCGGGGCTGGCCGCTGCTCATCGGCCTCTTCGCCGCCGGTTTCCTGGTGGTCTCCACATTCACGACG
ACGCTGGTGATGACTCAGGAGTACATGCCCCGCAGCCTGGGGCTGGCCTCGGGGCTCAACCTGGGCCTGGCCTTCGGCAT
GGGCGGCGTGGGCACCTCGGTGCTCGGCATCGTGGCCGACCACTTCGGCGTGCTCGTGGTGATGCGGTGCATCGCATCGC
TGGTGCTGCCGGCGCTGCTGCTCACGCTGGCGCTGCCGCCGGTCCGGCTGAACCGGGCCTGA

Upstream 100 bases:

>100_bases
AGACTCCTCCAGCGGCCCGAGGAAGGATCCGCGGGGTTCCGGAGCGAAGGCAACTCGCTACGCTCTATGATATCAGCCGC
GCAAGGAGGATCTGAAGCCC

Downstream 100 bases:

>100_bases
GGCGGCCGTTGCGGCGGCGGTCAAGCTGTGATATAGTCATGGGTGCAGACGGGAGTAGATCGGGTCCTGGTGGCCCGCAC
GGTCTTCAAAACCGCTTGAG

Product: putative fosmidmycin resistance protein

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNSTVSAGRPVLALLLVLSLTHAVIDLTSGAIVALLPAMREAYSLSYAMVGLIPLFANLTSTFTQPVFGIISDRSEMRWL
LPLSVALGGLGLAAVGYVSNYWLVLAAVVISALGSAAFHPEGAHAAHNLAGERRALAMAIYSVGGNLGYALGPGFAAALI
AAFGLRGTGLAALLPLALAAFLIWLLPRWRAHEQEAAARKREQAEPGETNWRGTVLITLVVILRSIIHLGMTTYVPFFWI
DVLGNAPATAGLVQTTYLLAGVLGTLLGAPLADRFGTKPVLIASFALLLPVQAVLASLRGWPLLIGLFAAGFLVVSTFTT
TLVMTQEYMPRSLGLASGLNLGLAFGMGGVGTSVLGIVADHFGVLVVMRCIASLVLPALLLTLALPPVRLNRA

Sequences:

>Translated_393_residues
MNSTVSAGRPVLALLLVLSLTHAVIDLTSGAIVALLPAMREAYSLSYAMVGLIPLFANLTSTFTQPVFGIISDRSEMRWL
LPLSVALGGLGLAAVGYVSNYWLVLAAVVISALGSAAFHPEGAHAAHNLAGERRALAMAIYSVGGNLGYALGPGFAAALI
AAFGLRGTGLAALLPLALAAFLIWLLPRWRAHEQEAAARKREQAEPGETNWRGTVLITLVVILRSIIHLGMTTYVPFFWI
DVLGNAPATAGLVQTTYLLAGVLGTLLGAPLADRFGTKPVLIASFALLLPVQAVLASLRGWPLLIGLFAAGFLVVSTFTT
TLVMTQEYMPRSLGLASGLNLGLAFGMGGVGTSVLGIVADHFGVLVVMRCIASLVLPALLLTLALPPVRLNRA
>Mature_393_residues
MNSTVSAGRPVLALLLVLSLTHAVIDLTSGAIVALLPAMREAYSLSYAMVGLIPLFANLTSTFTQPVFGIISDRSEMRWL
LPLSVALGGLGLAAVGYVSNYWLVLAAVVISALGSAAFHPEGAHAAHNLAGERRALAMAIYSVGGNLGYALGPGFAAALI
AAFGLRGTGLAALLPLALAAFLIWLLPRWRAHEQEAAARKREQAEPGETNWRGTVLITLVVILRSIIHLGMTTYVPFFWI
DVLGNAPATAGLVQTTYLLAGVLGTLLGAPLADRFGTKPVLIASFALLLPVQAVLASLRGWPLLIGLFAAGFLVVSTFTT
TLVMTQEYMPRSLGLASGLNLGLAFGMGGVGTSVLGIVADHFGVLVVMRCIASLVLPALLLTLALPPVRLNRA

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786686, Length=398, Percent_Identity=32.6633165829146, Blast_Score=149, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41047; Mature: 41047

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTVSAGRPVLALLLVLSLTHAVIDLTSGAIVALLPAMREAYSLSYAMVGLIPLFANLT
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STFTQPVFGIISDRSEMRWLLPLSVALGGLGLAAVGYVSNYWLVLAAVVISALGSAAFHP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGAHAAHNLAGERRALAMAIYSVGGNLGYALGPGFAAALIAAFGLRGTGLAALLPLALAA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FLIWLLPRWRAHEQEAAARKREQAEPGETNWRGTVLITLVVILRSIIHLGMTTYVPFFWI
HHHHHHCHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLGNAPATAGLVQTTYLLAGVLGTLLGAPLADRFGTKPVLIASFALLLPVQAVLASLRG
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
WPLLIGLFAAGFLVVSTFTTTLVMTQEYMPRSLGLASGLNLGLAFGMGGVGTSVLGIVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHCCCCHHHHHCCCCHHHHHHHHHHH
HFGVLVVMRCIASLVLPALLLTLALPPVRLNRA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSTVSAGRPVLALLLVLSLTHAVIDLTSGAIVALLPAMREAYSLSYAMVGLIPLFANLT
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STFTQPVFGIISDRSEMRWLLPLSVALGGLGLAAVGYVSNYWLVLAAVVISALGSAAFHP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGAHAAHNLAGERRALAMAIYSVGGNLGYALGPGFAAALIAAFGLRGTGLAALLPLALAA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FLIWLLPRWRAHEQEAAARKREQAEPGETNWRGTVLITLVVILRSIIHLGMTTYVPFFWI
HHHHHHCHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLGNAPATAGLVQTTYLLAGVLGTLLGAPLADRFGTKPVLIASFALLLPVQAVLASLRG
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
WPLLIGLFAAGFLVVSTFTTTLVMTQEYMPRSLGLASGLNLGLAFGMGGVGTSVLGIVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCHHCCCCHHHHHCCCCHHHHHHHHHHH
HFGVLVVMRCIASLVLPALLLTLALPPVRLNRA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]