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The map label for this gene is hppA [H]

Identifier: 51893700

GI number: 51893700

Start: 2749980

End: 2751959

Strand: Reverse

Name: hppA [H]

Synonym: STH2562

Alternate gene names: 51893700

Gene position: 2751959-2749980 (Counterclockwise)

Preceding gene: 51893701

Following gene: 51893699

Centisome position: 77.17

GC content: 68.99

Gene sequence:

>1980_bases
GTGCTCGCGCTCATCGTGGCCGGGCTGCTCGCCGCCAAGATCCGGGGGCAGGATCCAGGAACCCCGCGTATGCAGGAGAT
TGCCGCCGCCATCCATGACGGCGCCATGGCTTTCCTCAACCGGGAGTACCGGACCCTCGTCGTCTTCGTGCTCGCCCTGG
CTATCATCATCCTCATTGCGGGCTTCACCACCGATGCCATGCAGTGGCAGACCGCCATCGCCTTCGTGGCCGGCGCGCTC
TGCTCGGTGCTCGCCGGCAACTTCGGCATGCGGGTGGCCACCATGGCCAACGTCCGCACGGCCAACGCCGCGCAGCATGG
CCTGAACCGGGCCCTGGACATCGCCTTCTCGGGCGGCGCCGTGATGGGCCTCTCCGTCGTCGGCCTGGGCATGCTGGGCG
TCGGCGTGGTCTACCTGATCTTCCGTGACCCGGACATCGTCAACGGCTTCGCCCTCGGCGCCTCCTCCATCGCCCTGTTC
GCCCGCGTCGGCGGCGGCATCTACACCAAGGCCGCAGACGTCGGCGCTGACCTGGTGGGCAAGGTGGAGGCCGGCATTCC
GGAGGACGACCCCCGCAATCCGGCCGTCATCGCCGACAATGTCGGTGACAACGTGGGCGACGTCGCGGGCATGGGCGCCG
ACCTCTTTGAGTCCTACGTCGGCGCCGTCATCGCCGCGATGGCCATCGCCGTCGTCGACAAGGACATCGACCCGAATCTG
GCCGCGCTGCCCCTGCTGATCGCCGCCGGCGGCATCGTGGCATCGGTCATCGGCACCCAGTTCGTGCGCGGCAAGGAGGG
CGGCAACCCGGCCAAGGCCCTGAACGCGGGCACCTACGCCGCGGGCATCCTCACCCTTATCGTCGCCGCCGTCATCTCGT
TCCTGGGCTACGGCACTCACATCTACTTCACGGCCGTGGTGGCGGGCCTCATCGCCGGCATCGCCATCGGTCAGCTCACC
GAGTACTACACCTCTGGCGACTACGGCCCCGTCAAGTCCATCGCCGACGCCTCCCGGACCGGCCCGGCGACCAACATCAT
CTCCGGCCTGGGCGTCGGTATGATGTCCACCGCCCTGCCGATCCTGGTCATCGGCGCCGCCACGCTGGTCGGCTACCTGG
TGGGCGCGCCCCATGGCCAGGGGCTCTTCACCATCGCCCTGGCGGCCGTGGGCATGCTTTCCACCACGGGCATGACCGTC
GCGGTGGACGCCTACGGCCCCATCGCCGACAACGCCGGCGGCATCGCCGAGATGAGCCACCTGGATCCGAAGGTGCGCAA
GACCACCGACACCCTGGACTCGGTGGGCAACACCACCGCGGCCATCGGCAAGGGCTTCGCCATCGGTTCGGCGGCGCTGA
CCGCCCTGTCGCTCTTCGGCGCCTTCGCCACGGCCGCGGGCCTGGGTAACGTCTCCATGACCGATCCGAAGCTGATCGTC
GGCCTCTTCGTCGGCGGTATGCTGCCCTTCCTGTTCGGCGCGCTGACCATGAACGCCGTCGGCCGGGCCGCAATGCAGAT
GGTGGAGGAGGTCCGCCGGCAGTTCCGGGAGATCCCGGGCATCATGGAGGAGAAGGCCAAGCCCGACTACGCCCGCTGCG
TGGACATCTCCACGGGCGCTGCCCTGAAGGAGATGATCGTCCCCGGCCTGATGGCCGTGGCGGCGCCGCTGCTCACGGGC
TGGCTGCTGGGCGTCACGGCCCTGGCGGGCCTGCTGGCGGGCGCCCTGGTCACCGGCGTCATGATGGCCATCATGATGGC
CAACGCCGGCGGCGCGTGGGATAACGCGAAGAAGTACATCGAGGCCGGCGCCCACGGCGGCAAGGGTTCCGAGCCCCACA
AGGCGGCCGTCGTCGGCGACACGGTCGGCGACCCCTTCAAGGACACCTCCGGCCCGTCGATGAACATCCTGATCAAGCTG
ATGACCATCGTCTCGCTAGTCTTCGCCGCCACCTTCGGCAACGGGCTCCTGCCCTTCTAG

Upstream 100 bases:

>100_bases
TGGATAACTAGCATTGGGTCAGTCTATGCTAGTGTTTTGGAAAGGAGATCGGATCCCAGTGAACATGGCAAGTCTCGCCT
GGCTTGCCCCGGCGGCCGGC

Downstream 100 bases:

>100_bases
AGCCACTGAGTTCACCGAGGCCGCCCCGGCGACGGGGCGGCCTGCTCGTTCCGGGGCTTTTCCGAGTCGGCGACAGGGAT
CGCGCCCCGGGGCGGCGAAA

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MLALIVAGLLAAKIRGQDPGTPRMQEIAAAIHDGAMAFLNREYRTLVVFVLALAIIILIAGFTTDAMQWQTAIAFVAGAL
CSVLAGNFGMRVATMANVRTANAAQHGLNRALDIAFSGGAVMGLSVVGLGMLGVGVVYLIFRDPDIVNGFALGASSIALF
ARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGAVIAAMAIAVVDKDIDPNL
AALPLLIAAGGIVASVIGTQFVRGKEGGNPAKALNAGTYAAGILTLIVAAVISFLGYGTHIYFTAVVAGLIAGIAIGQLT
EYYTSGDYGPVKSIADASRTGPATNIISGLGVGMMSTALPILVIGAATLVGYLVGAPHGQGLFTIALAAVGMLSTTGMTV
AVDAYGPIADNAGGIAEMSHLDPKVRKTTDTLDSVGNTTAAIGKGFAIGSAALTALSLFGAFATAAGLGNVSMTDPKLIV
GLFVGGMLPFLFGALTMNAVGRAAMQMVEEVRRQFREIPGIMEEKAKPDYARCVDISTGAALKEMIVPGLMAVAAPLLTG
WLLGVTALAGLLAGALVTGVMMAIMMANAGGAWDNAKKYIEAGAHGGKGSEPHKAAVVGDTVGDPFKDTSGPSMNILIKL
MTIVSLVFAATFGNGLLPF

Sequences:

>Translated_659_residues
MLALIVAGLLAAKIRGQDPGTPRMQEIAAAIHDGAMAFLNREYRTLVVFVLALAIIILIAGFTTDAMQWQTAIAFVAGAL
CSVLAGNFGMRVATMANVRTANAAQHGLNRALDIAFSGGAVMGLSVVGLGMLGVGVVYLIFRDPDIVNGFALGASSIALF
ARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGAVIAAMAIAVVDKDIDPNL
AALPLLIAAGGIVASVIGTQFVRGKEGGNPAKALNAGTYAAGILTLIVAAVISFLGYGTHIYFTAVVAGLIAGIAIGQLT
EYYTSGDYGPVKSIADASRTGPATNIISGLGVGMMSTALPILVIGAATLVGYLVGAPHGQGLFTIALAAVGMLSTTGMTV
AVDAYGPIADNAGGIAEMSHLDPKVRKTTDTLDSVGNTTAAIGKGFAIGSAALTALSLFGAFATAAGLGNVSMTDPKLIV
GLFVGGMLPFLFGALTMNAVGRAAMQMVEEVRRQFREIPGIMEEKAKPDYARCVDISTGAALKEMIVPGLMAVAAPLLTG
WLLGVTALAGLLAGALVTGVMMAIMMANAGGAWDNAKKYIEAGAHGGKGSEPHKAAVVGDTVGDPFKDTSGPSMNILIKL
MTIVSLVFAATFGNGLLPF
>Mature_659_residues
MLALIVAGLLAAKIRGQDPGTPRMQEIAAAIHDGAMAFLNREYRTLVVFVLALAIIILIAGFTTDAMQWQTAIAFVAGAL
CSVLAGNFGMRVATMANVRTANAAQHGLNRALDIAFSGGAVMGLSVVGLGMLGVGVVYLIFRDPDIVNGFALGASSIALF
ARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGAVIAAMAIAVVDKDIDPNL
AALPLLIAAGGIVASVIGTQFVRGKEGGNPAKALNAGTYAAGILTLIVAAVISFLGYGTHIYFTAVVAGLIAGIAIGQLT
EYYTSGDYGPVKSIADASRTGPATNIISGLGVGMMSTALPILVIGAATLVGYLVGAPHGQGLFTIALAAVGMLSTTGMTV
AVDAYGPIADNAGGIAEMSHLDPKVRKTTDTLDSVGNTTAAIGKGFAIGSAALTALSLFGAFATAAGLGNVSMTDPKLIV
GLFVGGMLPFLFGALTMNAVGRAAMQMVEEVRRQFREIPGIMEEKAKPDYARCVDISTGAALKEMIVPGLMAVAAPLLTG
WLLGVTALAGLLAGALVTGVMMAIMMANAGGAWDNAKKYIEAGAHGGKGSEPHKAAVVGDTVGDPFKDTSGPSMNILIKL
MTIVSLVFAATFGNGLLPF

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 66604; Mature: 66604

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALIVAGLLAAKIRGQDPGTPRMQEIAAAIHDGAMAFLNREYRTLVVFVLALAIIILIA
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFTTDAMQWQTAIAFVAGALCSVLAGNFGMRVATMANVRTANAAQHGLNRALDIAFSGGA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHEEEECCCH
VMGLSVVGLGMLGVGVVYLIFRDPDIVNGFALGASSIALFARVGGGIYTKAADVGADLVG
HHHHHHHHHHHHHHHHHHHEECCCCHHCHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHH
KVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGAVIAAMAIAVVDKDIDPNL
HHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AALPLLIAAGGIVASVIGTQFVRGKEGGNPAKALNAGTYAAGILTLIVAAVISFLGYGTH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHH
IYFTAVVAGLIAGIAIGQLTEYYTSGDYGPVKSIADASRTGPATNIISGLGVGMMSTALP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILVIGAATLVGYLVGAPHGQGLFTIALAAVGMLSTTGMTVAVDAYGPIADNAGGIAEMSH
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHH
LDPKVRKTTDTLDSVGNTTAAIGKGFAIGSAALTALSLFGAFATAAGLGNVSMTDPKLIV
CCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
GLFVGGMLPFLFGALTMNAVGRAAMQMVEEVRRQFREIPGIMEEKAKPDYARCVDISTGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHEEECCCCH
ALKEMIVPGLMAVAAPLLTGWLLGVTALAGLLAGALVTGVMMAIMMANAGGAWDNAKKYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
EAGAHGGKGSEPHKAAVVGDTVGDPFKDTSGPSMNILIKLMTIVSLVFAATFGNGLLPF
HHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLALIVAGLLAAKIRGQDPGTPRMQEIAAAIHDGAMAFLNREYRTLVVFVLALAIIILIA
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFTTDAMQWQTAIAFVAGALCSVLAGNFGMRVATMANVRTANAAQHGLNRALDIAFSGGA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHEEEECCCH
VMGLSVVGLGMLGVGVVYLIFRDPDIVNGFALGASSIALFARVGGGIYTKAADVGADLVG
HHHHHHHHHHHHHHHHHHHEECCCCHHCHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHH
KVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGAVIAAMAIAVVDKDIDPNL
HHHCCCCCCCCCCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AALPLLIAAGGIVASVIGTQFVRGKEGGNPAKALNAGTYAAGILTLIVAAVISFLGYGTH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHH
IYFTAVVAGLIAGIAIGQLTEYYTSGDYGPVKSIADASRTGPATNIISGLGVGMMSTALP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILVIGAATLVGYLVGAPHGQGLFTIALAAVGMLSTTGMTVAVDAYGPIADNAGGIAEMSH
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHH
LDPKVRKTTDTLDSVGNTTAAIGKGFAIGSAALTALSLFGAFATAAGLGNVSMTDPKLIV
CCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
GLFVGGMLPFLFGALTMNAVGRAAMQMVEEVRRQFREIPGIMEEKAKPDYARCVDISTGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHEEECCCCH
ALKEMIVPGLMAVAAPLLTGWLLGVTALAGLLAGALVTGVMMAIMMANAGGAWDNAKKYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
EAGAHGGKGSEPHKAAVVGDTVGDPFKDTSGPSMNILIKLMTIVSLVFAATFGNGLLPF
HHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA