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The map label for this gene is licH [H]

Identifier: 51893588

GI number: 51893588

Start: 2637116

End: 2638471

Strand: Reverse

Name: licH [H]

Synonym: STH2450

Alternate gene names: 51893588

Gene position: 2638471-2637116 (Counterclockwise)

Preceding gene: 51893589

Following gene: 51893587

Centisome position: 73.99

GC content: 71.39

Gene sequence:

>1356_bases
TTGGCCGGTGCGGGCGAAGTATCAGGAAAGGGTTGGCATGCCACCCCGCAAGCGAGGGAAGGTGACCGCATGAAACTGAC
GATCATCGGCGGCGCAAGCGCATACACGCCGGACATCATCCTCGGCCTTCTCCAGGATCACGCCCTGTATGCCGGGGGCG
AGCTGTGCCTGCACGACATCGACGGCGCGAACCTGCGGGTGATCGAGCGGCTGGCACGGGCGCTGGTGCGGGCGGCGGGG
GCCGACCTGCGCGTCACGGCCACGCTGGACCGGGCGGAGGCCATCACCGGCTCCCGGTTCATCCTCACGCAGCCCCGGGT
CGGCGGGCTGCAGCACCGGGCCCTGGACGAGAAGATCCCCCTGAAGCACGGGCTGATCGGCCAGGAGACCCTGGGCCTGG
GCGGGTTCGCCTTCGCCTGGCGCACGATCCCGGTGATGCTGGAGATCGTGGAGGAGGTGCAGCGGCTCGCCCCGGAGGCG
TGGATCATCAACTACGCCAACCCTGCCGGCATGGTCACCGAGGCGGTGATCCGCCGCTTTCCCGACGCCCGGTTCATCGG
CCTCTGCGACATGCCCACGGGCCTGCAGTGGGCCATCGGCCGGCTGCTGCGGGTGGACTACCGCCGCATTGCCCTGGATT
ATGCCGGTATCAACCACGGCGGCTGGGTCAGCCGGGTGCTGCTGGACGGCGAGGACGTGACGGCGCGGCTGCGCCGCTGG
GCCGCCGCGCTGGGCCCGGTGGCGTCGCTGCTGCCGCTGGGCGAGCAGACGGGTACGGTGCGGCTCTTCCGCCAGCACGG
GATGGTGCCCGACCCCTATCTCCGGTACTACTACTACAAGGACCAGATCCTCAAGAAGCTGCTGCGGGCCGAGCGGACCC
GGGCCGAGTTCCTGATCGAGCGGGTGCAGCAGCTGTACCGCCACTACGCGGACGTGGCCGGGCAGGAGCAGCCGGTGCTG
AAGGAGCACCGGGGTCACCCGGCCCACTCGGACCTGGCCTCGCAGGTGATCGCCGCCATGGCGGCGAACCGGCCCACGCG
CTTCGTCATCCAGCAGCGCGGGGCCGGCGCCGTGCGCCACCTTCCGCCGGAGGAGGCAGCCCAGTTCTCGGCGATCGTCG
ACGGCAGCGGCTGGACGCCGATCCCCCAGCCGGCGCTGCCCCGGAAGGAGGCCGAGCTCATCGCCCGCATCAAGGCCTCG
GAGACGCTCAACGTGCGGGCTGCGATGGAGGGCGACCGGAGCCTGGCCGTGGAGGCCGCCGAGCTCAACCCGCTGGGGGC
GCCGCGGCCCCTCGCCGAGAAGGTCGTGGACGAGCTGCTGGCCGCGCACCGCAAGTACCTGCCGCAGTTCGCCTGA

Upstream 100 bases:

>100_bases
TGGCGGCTCCCAGGACAGTACAGGCGGCAGCCGATAGCGTGCGGGAAGGCCGTGCCACAGGGCAGGCCTTCCCGCTCTTT
TGGATTCTCTGACAGGGACT

Downstream 100 bases:

>100_bases
GGGCCGGCCATGCGGGGACTGATCGTCAACGCGGACGACTTCGGCCTCAGCCCGGGCGTCAGCCGGGGCATCCTGCGGGC
TCACTGGGAGGGCATCGTCA

Product: alpha-galactosidase/6-phospho-beta-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MAGAGEVSGKGWHATPQAREGDRMKLTIIGGASAYTPDIILGLLQDHALYAGGELCLHDIDGANLRVIERLARALVRAAG
ADLRVTATLDRAEAITGSRFILTQPRVGGLQHRALDEKIPLKHGLIGQETLGLGGFAFAWRTIPVMLEIVEEVQRLAPEA
WIINYANPAGMVTEAVIRRFPDARFIGLCDMPTGLQWAIGRLLRVDYRRIALDYAGINHGGWVSRVLLDGEDVTARLRRW
AAALGPVASLLPLGEQTGTVRLFRQHGMVPDPYLRYYYYKDQILKKLLRAERTRAEFLIERVQQLYRHYADVAGQEQPVL
KEHRGHPAHSDLASQVIAAMAANRPTRFVIQQRGAGAVRHLPPEEAAQFSAIVDGSGWTPIPQPALPRKEAELIARIKAS
ETLNVRAAMEGDRSLAVEAAELNPLGAPRPLAEKVVDELLAAHRKYLPQFA

Sequences:

>Translated_451_residues
MAGAGEVSGKGWHATPQAREGDRMKLTIIGGASAYTPDIILGLLQDHALYAGGELCLHDIDGANLRVIERLARALVRAAG
ADLRVTATLDRAEAITGSRFILTQPRVGGLQHRALDEKIPLKHGLIGQETLGLGGFAFAWRTIPVMLEIVEEVQRLAPEA
WIINYANPAGMVTEAVIRRFPDARFIGLCDMPTGLQWAIGRLLRVDYRRIALDYAGINHGGWVSRVLLDGEDVTARLRRW
AAALGPVASLLPLGEQTGTVRLFRQHGMVPDPYLRYYYYKDQILKKLLRAERTRAEFLIERVQQLYRHYADVAGQEQPVL
KEHRGHPAHSDLASQVIAAMAANRPTRFVIQQRGAGAVRHLPPEEAAQFSAIVDGSGWTPIPQPALPRKEAELIARIKAS
ETLNVRAAMEGDRSLAVEAAELNPLGAPRPLAEKVVDELLAAHRKYLPQFA
>Mature_450_residues
AGAGEVSGKGWHATPQAREGDRMKLTIIGGASAYTPDIILGLLQDHALYAGGELCLHDIDGANLRVIERLARALVRAAGA
DLRVTATLDRAEAITGSRFILTQPRVGGLQHRALDEKIPLKHGLIGQETLGLGGFAFAWRTIPVMLEIVEEVQRLAPEAW
IINYANPAGMVTEAVIRRFPDARFIGLCDMPTGLQWAIGRLLRVDYRRIALDYAGINHGGWVSRVLLDGEDVTARLRRWA
AALGPVASLLPLGEQTGTVRLFRQHGMVPDPYLRYYYYKDQILKKLLRAERTRAEFLIERVQQLYRHYADVAGQEQPVLK
EHRGHPAHSDLASQVIAAMAANRPTRFVIQQRGAGAVRHLPPEEAAQFSAIVDGSGWTPIPQPALPRKEAELIARIKASE
TLNVRAAMEGDRSLAVEAAELNPLGAPRPLAEKVVDELLAAHRKYLPQFA

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=440, Percent_Identity=33.8636363636364, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1790560, Length=449, Percent_Identity=25.8351893095768, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 49622; Mature: 49491

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAGEVSGKGWHATPQAREGDRMKLTIIGGASAYTPDIILGLLQDHALYAGGELCLHDI
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECC
DGANLRVIERLARALVRAAGADLRVTATLDRAEAITGSRFILTQPRVGGLQHRALDEKIP
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCEEEEECCCCCCCHHHHCCCCCC
LKHGLIGQETLGLGGFAFAWRTIPVMLEIVEEVQRLAPEAWIINYANPAGMVTEAVIRRF
HHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHC
PDARFIGLCDMPTGLQWAIGRLLRVDYRRIALDYAGINHGGWVSRVLLDGEDVTARLRRW
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHEEEEECCCHHHHHHHHH
AAALGPVASLLPLGEQTGTVRLFRQHGMVPDPYLRYYYYKDQILKKLLRAERTRAEFLIE
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQQLYRHYADVAGQEQPVLKEHRGHPAHSDLASQVIAAMAANRPTRFVIQQRGAGAVRH
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
LPPEEAAQFSAIVDGSGWTPIPQPALPRKEAELIARIKASETLNVRAAMEGDRSLAVEAA
CCHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEH
ELNPLGAPRPLAEKVVDELLAAHRKYLPQFA
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGAGEVSGKGWHATPQAREGDRMKLTIIGGASAYTPDIILGLLQDHALYAGGELCLHDI
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECC
DGANLRVIERLARALVRAAGADLRVTATLDRAEAITGSRFILTQPRVGGLQHRALDEKIP
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCEEEEECCCCCCCHHHHCCCCCC
LKHGLIGQETLGLGGFAFAWRTIPVMLEIVEEVQRLAPEAWIINYANPAGMVTEAVIRRF
HHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHC
PDARFIGLCDMPTGLQWAIGRLLRVDYRRIALDYAGINHGGWVSRVLLDGEDVTARLRRW
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHEEEEECCCHHHHHHHHH
AAALGPVASLLPLGEQTGTVRLFRQHGMVPDPYLRYYYYKDQILKKLLRAERTRAEFLIE
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQQLYRHYADVAGQEQPVLKEHRGHPAHSDLASQVIAAMAANRPTRFVIQQRGAGAVRH
HHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
LPPEEAAQFSAIVDGSGWTPIPQPALPRKEAELIARIKASETLNVRAAMEGDRSLAVEAA
CCHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEH
ELNPLGAPRPLAEKVVDELLAAHRKYLPQFA
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]