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The map label for this gene is metC [H]

Identifier: 51893500

GI number: 51893500

Start: 2553001

End: 2553228

Strand: Reverse

Name: metC [H]

Synonym: STH2362

Alternate gene names: 51893500

Gene position: 2553228-2553001 (Counterclockwise)

Preceding gene: 51893501

Following gene: 51893499

Centisome position: 71.6

GC content: 70.18

Gene sequence:

>228_bases
TTGGAGTTTGGGACGCGGGTTCTGCACACGGGGCGCGAGGTGGACTCCGTCACGGGCGCGGCCGCCGTGCCCATCTACCA
GGTTTCCACGTTCCGTCAACCCGGGCTGAACCGCTCGGGTCCGTACGATTACGCCCGCTCGGGCAACCCGACCCGCCAGG
CCCTGGAGGCCATCGTCGCCGACCTGGAGCAGGCGCTCGGGTATGCGGCGGCGCAGTCTGGGGTCTGA

Upstream 100 bases:

>100_bases
CGGCTGGGCATCACGGACCGGCTGCTGCGGCTCTCGGTGGGCATCGAGGACGCCGACGACCTGATCGCCGATCTTGCTCA
GGCGCTGGAGGGATAGAGCC

Downstream 100 bases:

>100_bases
TCCCGGGCCCGGTTCGAGGCGGAATGTGCACCTGTGGTCTGTGGTGGGGTGCACATTCCGCCTGCTGCGTGCGTGGTCAG
CAGGGAGTTCGAGGCGAAAT

Product: cystathionine beta-lyase

Products: NA

Alternate protein names: CBL; Beta-cystathionase; Cysteine lyase [H]

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MEFGTRVLHTGREVDSVTGAAAVPIYQVSTFRQPGLNRSGPYDYARSGNPTRQALEAIVADLEQALGYAAAQSGV

Sequences:

>Translated_75_residues
MEFGTRVLHTGREVDSVTGAAAVPIYQVSTFRQPGLNRSGPYDYARSGNPTRQALEAIVADLEQALGYAAAQSGV
>Mature_75_residues
MEFGTRVLHTGREVDSVTGAAAVPIYQVSTFRQPGLNRSGPYDYARSGNPTRQALEAIVADLEQALGYAAAQSGV

Specific function: The enzymatic degradation of amino acids in cheese is believed to generate aroma compounds and therefore to be essential for flavor development. Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine but is also able to catalyze an alpha

COG id: COG0626

COG function: function code E; Cystathionine beta-lyases/cystathionine gamma-synthases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trans-sulfuration enzymes family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000277
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01053 Cys_Met_Meta_PP [H]

EC number: =4.4.1.8 [H]

Molecular weight: Translated: 7955; Mature: 7955

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFGTRVLHTGREVDSVTGAAAVPIYQVSTFRQPGLNRSGPYDYARSGNPTRQALEAIVA
CCCCCHHHHCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DLEQALGYAAAQSGV
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFGTRVLHTGREVDSVTGAAAVPIYQVSTFRQPGLNRSGPYDYARSGNPTRQALEAIVA
CCCCCHHHHCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
DLEQALGYAAAQSGV
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]