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The map label for this gene is alsK [H]

Identifier: 51893477

GI number: 51893477

Start: 2526234

End: 2527154

Strand: Reverse

Name: alsK [H]

Synonym: STH2339

Alternate gene names: 51893477

Gene position: 2527154-2526234 (Counterclockwise)

Preceding gene: 51893478

Following gene: 51893476

Centisome position: 70.87

GC content: 65.26

Gene sequence:

>921_bases
TTGTACGACGACGTCGTCCTGGGCATCGACCTGGGTGGCACTCACCTGCGGTTGGGGCTCGTGGACCGGAACTACCAAGT
ATCGCAGTTCGAGATTCGGAAGACGAGGGAGATTCTCCAGGGCGACCGTCCCGTGCAGCGGCTGATCGACACCGTGTCCG
CATACATCGCCGCTCACCTTGGCGACCGGCTGCCGGCCGCCGTCGCCGTCGGCTTCCCCTCCACGGTGGACCGGACCAGG
CGGGTCGTGATGTCCACCCCCAACATTCCGGGGTTGAATGACCTGCCGGTCGCCGACCTGATGGAGCAGGCGCTAGGCGT
GCCCGTGTTCGTCAACCGGGACGTGAACTTCCTGATGCTGCACGACCTCCTGGCGCACGACCTCGAAGGGCTGCCCATCG
TGCTCGGTTTTTATGTGGGGACCGGTTTCGGGAACGCCGTCTTCCTGGACGGCAGGCTGCTCACGGGCAGGCACGGCATG
GCCGCTGAACTGGGCCACGTGCCGCTGTTCCGGCTGCAGGACCGCTGTGGATGCGGAAACCCGGGGTGCGCCGAGATCAT
CGCGTCGGGCCTGCGGCTGGAACGGATCCAACAGGAGCAGTTCCCGGACGTTCCGCTGGAGGAGCTGTTCATCCGGCATG
CGTCCCATCCGGCGCTGCGGCAGTTCGTCGAGGACCTCTCGCTGCCCATCGCCACGGAGATCAACATCTTCGATCCGGAC
TGCATCATCCTGGGCGGCGGAATCCTGCACATGGAAGGGTTTCCCCGGGCCGAGTTGGAAGCCGCCATCTACCGGCACGC
GCGCAAACCCTACCCGGGACTCGACTTCCGCATCATCTACGCGGCGCCCAACCAGGAGAGCGGCGTGATCGGTGCGGGGA
TCTACGCCTACAAGCGACTTCAGAACCCGAGTTACCTCTGA

Upstream 100 bases:

>100_bases
GCCCTGATCATCGTCGCCGTCACCCTGGACCGCTTCTTCGGCGCGAGCCGCAAGCGTGGATAAGCGTGCGGCCGGCCCGC
ACGACGAGGAGGTCATCGAC

Downstream 100 bases:

>100_bases
GAAAGGAGACAACTGCCTTGTCGGTGTTGCTGTGCCCGTCGATGATGTGCGCCCATTTCGGCAACCTCGCCCATGAGGTG
GCCGAACTGGAGGCCGCCGG

Product: D-allose kinase

Products: NA

Alternate protein names: Allokinase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MYDDVVLGIDLGGTHLRLGLVDRNYQVSQFEIRKTREILQGDRPVQRLIDTVSAYIAAHLGDRLPAAVAVGFPSTVDRTR
RVVMSTPNIPGLNDLPVADLMEQALGVPVFVNRDVNFLMLHDLLAHDLEGLPIVLGFYVGTGFGNAVFLDGRLLTGRHGM
AAELGHVPLFRLQDRCGCGNPGCAEIIASGLRLERIQQEQFPDVPLEELFIRHASHPALRQFVEDLSLPIATEINIFDPD
CIILGGGILHMEGFPRAELEAAIYRHARKPYPGLDFRIIYAAPNQESGVIGAGIYAYKRLQNPSYL

Sequences:

>Translated_306_residues
MYDDVVLGIDLGGTHLRLGLVDRNYQVSQFEIRKTREILQGDRPVQRLIDTVSAYIAAHLGDRLPAAVAVGFPSTVDRTR
RVVMSTPNIPGLNDLPVADLMEQALGVPVFVNRDVNFLMLHDLLAHDLEGLPIVLGFYVGTGFGNAVFLDGRLLTGRHGM
AAELGHVPLFRLQDRCGCGNPGCAEIIASGLRLERIQQEQFPDVPLEELFIRHASHPALRQFVEDLSLPIATEINIFDPD
CIILGGGILHMEGFPRAELEAAIYRHARKPYPGLDFRIIYAAPNQESGVIGAGIYAYKRLQNPSYL
>Mature_306_residues
MYDDVVLGIDLGGTHLRLGLVDRNYQVSQFEIRKTREILQGDRPVQRLIDTVSAYIAAHLGDRLPAAVAVGFPSTVDRTR
RVVMSTPNIPGLNDLPVADLMEQALGVPVFVNRDVNFLMLHDLLAHDLEGLPIVLGFYVGTGFGNAVFLDGRLLTGRHGM
AAELGHVPLFRLQDRCGCGNPGCAEIIASGLRLERIQQEQFPDVPLEELFIRHASHPALRQFVEDLSLPIATEINIFDPD
CIILGGGILHMEGFPRAELEAAIYRHARKPYPGLDFRIIYAAPNQESGVIGAGIYAYKRLQNPSYL

Specific function: Catalyzes the phosphorylation of D-allose to D-allose 6- P. Has also low level glucokinase activity in vitro [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1790522, Length=304, Percent_Identity=37.5, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1787363, Length=263, Percent_Identity=25.4752851711027, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081733, Length=265, Percent_Identity=27.5471698113208, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786891, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787878, Length=238, Percent_Identity=25.2100840336134, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082230, Length=285, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.55 [H]

Molecular weight: Translated: 33768; Mature: 33768

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDDVVLGIDLGGTHLRLGLVDRNYQVSQFEIRKTREILQGDRPVQRLIDTVSAYIAAHL
CCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GDRLPAAVAVGFPSTVDRTRRVVMSTPNIPGLNDLPVADLMEQALGVPVFVNRDVNFLML
CCCCCCEEEECCCHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCCCCHHHH
HDLLAHDLEGLPIVLGFYVGTGFGNAVFLDGRLLTGRHGMAAELGHVPLFRLQDRCGCGN
HHHHHHCCCCCCEEEEEEHHCCCCCEEEECCEEEECCCCCHHHHCCCCCEEEHHHCCCCC
PGCAEIIASGLRLERIQQEQFPDVPLEELFIRHASHPALRQFVEDLSLPIATEINIFDPD
CCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEECCC
CIILGGGILHMEGFPRAELEAAIYRHARKPYPGLDFRIIYAAPNQESGVIGAGIYAYKRL
EEEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHC
QNPSYL
CCCCCC
>Mature Secondary Structure
MYDDVVLGIDLGGTHLRLGLVDRNYQVSQFEIRKTREILQGDRPVQRLIDTVSAYIAAHL
CCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GDRLPAAVAVGFPSTVDRTRRVVMSTPNIPGLNDLPVADLMEQALGVPVFVNRDVNFLML
CCCCCCEEEECCCHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCCCCHHHH
HDLLAHDLEGLPIVLGFYVGTGFGNAVFLDGRLLTGRHGMAAELGHVPLFRLQDRCGCGN
HHHHHHCCCCCCEEEEEEHHCCCCCEEEECCEEEECCCCCHHHHCCCCCEEEHHHCCCCC
PGCAEIIASGLRLERIQQEQFPDVPLEELFIRHASHPALRQFVEDLSLPIATEINIFDPD
CCHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEECCC
CIILGGGILHMEGFPRAELEAAIYRHARKPYPGLDFRIIYAAPNQESGVIGAGIYAYKRL
EEEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHC
QNPSYL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9401019 [H]