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The map label for this gene is alsE [H]

Identifier: 51893476

GI number: 51893476

Start: 2525548

End: 2526189

Strand: Reverse

Name: alsE [H]

Synonym: STH2338

Alternate gene names: 51893476

Gene position: 2526189-2525548 (Counterclockwise)

Preceding gene: 51893477

Following gene: 51893475

Centisome position: 70.84

GC content: 65.89

Gene sequence:

>642_bases
ATGTGCGCCCATTTCGGCAACCTCGCCCATGAGGTGGCCGAACTGGAGGCCGCCGGGATCGACATGTTTCACCTGGATGT
GATGGATGGTCGGTTCGTGCCGAACTTTGGCATGGGGCTGCAGGACATCGAGTTCATTGCCGCCCACGCCACCAAGCCGG
CGGACGTCCACCTGATGATCGAGGACCCGGGGAACTACGTGGAGAAGTTCGCGAAACTGGGCATCAAGGTCATCTACACC
CATCCGGAGGCGGACTACCATCCGGCGCGGACCTTGCTGAAGATCGCCGACGCCGGCGCCGCCCCGGGGATCGCGATCAA
CCCCGGGACGCCGGTGGAGGCCATCGAGCCGCTGCTCCATCTGGCCCAGTACGTCCTGGTCATGACCGTGAATCCCGGGT
TCGCCGGGCAGCCATACCTGTCGTTCGTTGACGAGAAGGTCGACCGCCTGGCGGAGTTGAAGGAGCGCTACGGTTACCGC
ATCGTGATCGACGGTGCGTGCACGGCAGCCGTGGTCGAGCGTCTGGCCCCGCGCGGCGTGGACGGGTTCGTGCTCGGGAC
CAAGGGACTCTTCGGCAGGGGCAAGCCCTACGGCGAGGTGATCGCGGAACTGCGCAGCCGGAGCGGCGACTGCCGGCGTT
GA

Upstream 100 bases:

>100_bases
TGATCGGTGCGGGGATCTACGCCTACAAGCGACTTCAGAACCCGAGTTACCTCTGAGAAAGGAGACAACTGCCTTGTCGG
TGTTGCTGTGCCCGTCGATG

Downstream 100 bases:

>100_bases
CGCTGGACGAGCCAAGACGGAGGAGCGGGAAGCGGATGAGGATTGCCATCGGCAATGATCACGTGGGTACGGAGATGAAG
CGGGCCATCGCGGCCCACCT

Product: ribulose-5-phosphate 3-epimerase

Products: D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MCAHFGNLAHEVAELEAAGIDMFHLDVMDGRFVPNFGMGLQDIEFIAAHATKPADVHLMIEDPGNYVEKFAKLGIKVIYT
HPEADYHPARTLLKIADAGAAPGIAINPGTPVEAIEPLLHLAQYVLVMTVNPGFAGQPYLSFVDEKVDRLAELKERYGYR
IVIDGACTAAVVERLAPRGVDGFVLGTKGLFGRGKPYGEVIAELRSRSGDCRR

Sequences:

>Translated_213_residues
MCAHFGNLAHEVAELEAAGIDMFHLDVMDGRFVPNFGMGLQDIEFIAAHATKPADVHLMIEDPGNYVEKFAKLGIKVIYT
HPEADYHPARTLLKIADAGAAPGIAINPGTPVEAIEPLLHLAQYVLVMTVNPGFAGQPYLSFVDEKVDRLAELKERYGYR
IVIDGACTAAVVERLAPRGVDGFVLGTKGLFGRGKPYGEVIAELRSRSGDCRR
>Mature_213_residues
MCAHFGNLAHEVAELEAAGIDMFHLDVMDGRFVPNFGMGLQDIEFIAAHATKPADVHLMIEDPGNYVEKFAKLGIKVIYT
HPEADYHPARTLLKIADAGAAPGIAINPGTPVEAIEPLLHLAQYVLVMTVNPGFAGQPYLSFVDEKVDRLAELKERYGYR
IVIDGACTAAVVERLAPRGVDGFVLGTKGLFGRGKPYGEVIAELRSRSGDCRR

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=188, Percent_Identity=31.9148936170213, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI219879828, Length=188, Percent_Identity=30.3191489361702, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1790523, Length=205, Percent_Identity=39.0243902439024, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789788, Length=212, Percent_Identity=35.377358490566, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1790754, Length=147, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17552948, Length=193, Percent_Identity=37.3056994818653, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322341, Length=228, Percent_Identity=31.140350877193, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24586301, Length=207, Percent_Identity=33.8164251207729, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: 5.1.3.1

Molecular weight: Translated: 23145; Mature: 23145

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAHFGNLAHEVAELEAAGIDMFHLDVMDGRFVPNFGMGLQDIEFIAAHATKPADVHLMI
CCCCHHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCCCHHHHHHHHHCCCCCCEEEEEE
EDPGNYVEKFAKLGIKVIYTHPEADYHPARTLLKIADAGAAPGIAINPGTPVEAIEPLLH
ECCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHH
LAQYVLVMTVNPGFAGQPYLSFVDEKVDRLAELKERYGYRIVIDGACTAAVVERLAPRGV
HHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCC
DGFVLGTKGLFGRGKPYGEVIAELRSRSGDCRR
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MCAHFGNLAHEVAELEAAGIDMFHLDVMDGRFVPNFGMGLQDIEFIAAHATKPADVHLMI
CCCCHHHHHHHHHHHHHCCCEEEEEEECCCEECCCCCCCHHHHHHHHHCCCCCCEEEEEE
EDPGNYVEKFAKLGIKVIYTHPEADYHPARTLLKIADAGAAPGIAINPGTPVEAIEPLLH
ECCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHH
LAQYVLVMTVNPGFAGQPYLSFVDEKVDRLAELKERYGYRIVIDGACTAAVVERLAPRGV
HHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCCCC
DGFVLGTKGLFGRGKPYGEVIAELRSRSGDCRR
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-ribulose 5-phosphate

Specific reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9401019 [H]