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The map label for this gene is dmsB1 [H]

Identifier: 51893469

GI number: 51893469

Start: 2517292

End: 2517888

Strand: Reverse

Name: dmsB1 [H]

Synonym: STH2331

Alternate gene names: 51893469

Gene position: 2517888-2517292 (Counterclockwise)

Preceding gene: 51893470

Following gene: 51893468

Centisome position: 70.61

GC content: 67.17

Gene sequence:

>597_bases
ATGCAATACGGGTTCTTCATCGATGCCAAGTACTGCGCCGGATGCAAGACCTGCCAGATCGCCTGTAAGGACCGGGCGAG
CCTCGAGGTTGGCCAGCTGTTCCGCAAGGTGGTGAACTACGAGGACGGCGGCTGGGTGCAGCGCGGTGAAGGCTGGGTCC
ACAACGTCACCTCGTACTGGTTCTCCATCAGCTGCAACCACTGCGCCGATCCGGCCTGCGTGTACGTCTGCCCCACCGGG
GCGATGTACAAGCGGTCCGACAACGGCCTCGTGCTCGTGAACCAGGACGACTGCGTGGGGTGCCAGAGCTGCGTCTGGGC
CTGCCCGTACGACGCCCCCCAGTACAACCCTGAGGTGGGCAGGGTGCACAAGTGCGACGGCTGCATCGACCGGGTGGAGG
CCGGGCAGCGGCCGGTCTGCGTGGACGCCTGCCCGTACCAGCTGATCGACTTCGGCGACATCGAGGAACTGCGGGCCAAG
CACGGCGGCACGGCCTGGGTGCAGGGGCTGGCCGATCCGTCCCGTACCCGCCCGTCCCTCCTGGTCAACCCGCCGACCGG
GGCCATCAGCTCGCCGATTGGAGGGAGCCGCAAGTGA

Upstream 100 bases:

>100_bases
TCAACGTGCTGACCAAGTACCATCCGACCCCGGGCGCCAAGGGCAACCCCCAGCACACCAACCTGGTCCAGGTGGCCAAG
CTCTGAGGAGGTGAGCAGGA

Downstream 100 bases:

>100_bases
ACATGCACGACTGGTCGTTGATTCTCTACACGCTCTGCCTGCAGTCGTCCGTGGGCATCTACGTGGCGAGCCGGCTGGTG
CTGTGGAATGCGGAATCGAA

Product: anaerobic dimethyl sulfoxide reductase subunit B

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MQYGFFIDAKYCAGCKTCQIACKDRASLEVGQLFRKVVNYEDGGWVQRGEGWVHNVTSYWFSISCNHCADPACVYVCPTG
AMYKRSDNGLVLVNQDDCVGCQSCVWACPYDAPQYNPEVGRVHKCDGCIDRVEAGQRPVCVDACPYQLIDFGDIEELRAK
HGGTAWVQGLADPSRTRPSLLVNPPTGAISSPIGGSRK

Sequences:

>Translated_198_residues
MQYGFFIDAKYCAGCKTCQIACKDRASLEVGQLFRKVVNYEDGGWVQRGEGWVHNVTSYWFSISCNHCADPACVYVCPTG
AMYKRSDNGLVLVNQDDCVGCQSCVWACPYDAPQYNPEVGRVHKCDGCIDRVEAGQRPVCVDACPYQLIDFGDIEELRAK
HGGTAWVQGLADPSRTRPSLLVNPPTGAISSPIGGSRK
>Mature_198_residues
MQYGFFIDAKYCAGCKTCQIACKDRASLEVGQLFRKVVNYEDGGWVQRGEGWVHNVTSYWFSISCNHCADPACVYVCPTG
AMYKRSDNGLVLVNQDDCVGCQSCVWACPYDAPQYNPEVGRVHKCDGCIDRVEAGQRPVCVDACPYQLIDFGDIEELRAK
HGGTAWVQGLADPSRTRPSLLVNPPTGAISSPIGGSRK

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=195, Percent_Identity=50.7692307692308, Blast_Score=207, Evalue=4e-55,
Organism=Escherichia coli, GI1787872, Length=195, Percent_Identity=50.7692307692308, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1787749, Length=160, Percent_Identity=35.625, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790326, Length=163, Percent_Identity=35.5828220858896, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI2367345, Length=157, Percent_Identity=35.6687898089172, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1789370, Length=180, Percent_Identity=31.6666666666667, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1787478, Length=117, Percent_Identity=36.7521367521368, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787740, Length=94, Percent_Identity=40.4255319148936, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI226510944, Length=165, Percent_Identity=34.5454545454545, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI2367245, Length=167, Percent_Identity=30.5389221556886, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI87082179, Length=162, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082180, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789067, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788811, Length=163, Percent_Identity=31.2883435582822, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787963, Length=148, Percent_Identity=27.7027027027027, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 21698; Mature: 21698

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
8.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYGFFIDAKYCAGCKTCQIACKDRASLEVGQLFRKVVNYEDGGWVQRGEGWVHNVTSYW
CCCEEEEECHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCEEECEEEE
FSISCNHCADPACVYVCPTGAMYKRSDNGLVLVNQDDCVGCQSCVWACPYDAPQYNPEVG
EEEECCCCCCCEEEEECCCCCEEEECCCCEEEECCCCCCCCCHHEEECCCCCCCCCCCCC
RVHKCDGCIDRVEAGQRPVCVDACPYQLIDFGDIEELRAKHGGTAWVQGLADPSRTRPSL
CEECCHHHHHHHHCCCCCEEECCCCCEEECCCCHHHHHHHCCCHHEECCCCCCCCCCCCE
LVNPPTGAISSPIGGSRK
EEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MQYGFFIDAKYCAGCKTCQIACKDRASLEVGQLFRKVVNYEDGGWVQRGEGWVHNVTSYW
CCCEEEEECHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCEEECEEEE
FSISCNHCADPACVYVCPTGAMYKRSDNGLVLVNQDDCVGCQSCVWACPYDAPQYNPEVG
EEEECCCCCCCEEEEECCCCCEEEECCCCEEEECCCCCCCCCHHEEECCCCCCCCCCCCC
RVHKCDGCIDRVEAGQRPVCVDACPYQLIDFGDIEELRAKHGGTAWVQGLADPSRTRPSL
CEECCHHHHHHHHCCCCCEEECCCCCEEECCCCHHHHHHHCCCHHEECCCCCCCCCCCCE
LVNPPTGAISSPIGGSRK
EEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8635740 [H]