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The map label for this gene is dppA [H]

Identifier: 51893453

GI number: 51893453

Start: 2500214

End: 2501857

Strand: Reverse

Name: dppA [H]

Synonym: STH2315

Alternate gene names: 51893453

Gene position: 2501857-2500214 (Counterclockwise)

Preceding gene: 51893454

Following gene: 51893452

Centisome position: 70.16

GC content: 66.79

Gene sequence:

>1644_bases
GTGCTTTCCGCGTGCGGCAGCTCCTCGCCCAGCGGCACTGACGGCGGCTCGCAGAGCGGGGGCCAGACCGACACGACGCC
CAGCACGCAGGACGGCGGTTCGACGACGCCTGCGCCCCAGCAGCCCGCCGCCCAGGAGAAGGTGCTCGTCTGGGGCCGCG
GCGGCGACTCGGTCTCGCTGGACCCGATTCAGGTGACCGACGGTGAGTCGCTCAAGGTGACGCACCAGATCTACGAGGGC
CTGCTGGATTACGCGCCGGGCAGCACGGAGGTCGTTCCCGTGCTGGCCACCGAATGGGAGGCCAGCCCCGACGGCCTGGA
GTGGACCTTCAAGCTCCGCCAGGGCGTCAAGTTCCACGACGGCACGGACTTCAACGCGGAGGCCGTGAAGATCAACTTCG
ACCGGTGGCGCAACACCTCCGACCCGCTGCACGTGGGTGGCGAGTTCCCGTACTACAGCTACATGTTCGGCGGCTTCGAC
GAGGCCTCGAACATCCAGGACGTGATCGTGGTCGATGACTACACGGTCAAGTTTGTCCTGAAGAACATACAGGCCTCGTT
CCTGCAGGACATCGCCATGGTGCCCTTCGCGATTGCCAGCCCGAAGGCGCTGCAGGAGAACCCCGAGCGGCTCAATGATC
ATCCGGTGGGCACCGGTCCCTTCAGGTTCGTCTCCTGGACCAAGGGCGACCGCATCGTGCTGGAGGCCAACCCGGATTAC
TGGGGCGGCAAGCCGGCCATCGACCGGCTGATCTACCGGTCGATCCCGGACAACAACGCCCGCCTGGTCGCCCTGCAGGC
CGGCGAGCTGGACGTGATGGACGGCGTGGAGCCCGCCTTCCTGCCCACGATCCAGGCCACGGGCCAGTTTGACATCATCG
AGCGGCCGCCGATGAACATCGGTTACCTGGCCTTCAACACCCAGAAGCCGCCGTTTGACAACGTGTTGATCCGCCGGGCG
ATCAACCACGCCATCAACAAGGAGGAGCTGAACACCGCCTTCTACGGCGGCATGGGCATCCCGGCCGTCTCGCCGCTGCC
CCCCTCGGTCTGGGGCCACAACCCGAACGTGCCCAAGTACGAGTACGATCCCGAGAAGGCGAAGGAGCTGCTGGCCCAGG
CCGGCTACGGGCCGGACAACCCGCTGAAGACCGAGCTCTGGGCCATGCCGGTGCCGCGGCCGTACATGCCGCAGCCGGAG
CGCATCGGCGTCGCCATCCAGAACTACCTGCGCGAGGTGGGCATCGAGGCGGAGATCGTGACCTACGAGTGGGGCACCTA
CCTCGAGAAGACCGGCATGGGCGAGCACACCATGGCCCTGCTGGGCTGGACGGGCGACAACGGCGACCCGGACAACTTCC
TCTACGTGCTACTGGACAAGGACAACGCCGTCACGCCTGACGCCGGCAACATCGCCTTCTACGTCAACGACGAGGTGCAC
GACCTCCTTATCCGGGCCCGCCAGACCACCGACCAGGCGGAGCGCACCCGGCTGTACGAGGAGGCCCAGGTGAAGATCAT
GGAGGACGCGCCGTGGGTCCCGCTCATGCACACCCGCGTGCCCATCGCCGTCCGCAAGGGCATCACCGGGTACGTGCCCA
ACCCGACCGGCTCCGAGTCGCTGGCCAAGGTCTCCTTGCCGTAA

Upstream 100 bases:

>100_bases
GGCACCGGGCCCGGCACACACAGAGGGAGGGATTCGGCTCATGGGGGTTCGCACCAAGCGGTTCCGGTGGGCGGTCGGCC
TGTTCCTCGCGGCGGCGTTG

Downstream 100 bases:

>100_bases
CGGGAATGTCGCAGCAGTCCGCAGGGGGGCGGCGTCTGCCGCCCCCCTCCGGGCACACAGGGAGGGATCGCTATCGTCCG
CTATCTGGCCAAGCGGATCG

Product: dipeptide ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MLSACGSSSPSGTDGGSQSGGQTDTTPSTQDGGSTTPAPQQPAAQEKVLVWGRGGDSVSLDPIQVTDGESLKVTHQIYEG
LLDYAPGSTEVVPVLATEWEASPDGLEWTFKLRQGVKFHDGTDFNAEAVKINFDRWRNTSDPLHVGGEFPYYSYMFGGFD
EASNIQDVIVVDDYTVKFVLKNIQASFLQDIAMVPFAIASPKALQENPERLNDHPVGTGPFRFVSWTKGDRIVLEANPDY
WGGKPAIDRLIYRSIPDNNARLVALQAGELDVMDGVEPAFLPTIQATGQFDIIERPPMNIGYLAFNTQKPPFDNVLIRRA
INHAINKEELNTAFYGGMGIPAVSPLPPSVWGHNPNVPKYEYDPEKAKELLAQAGYGPDNPLKTELWAMPVPRPYMPQPE
RIGVAIQNYLREVGIEAEIVTYEWGTYLEKTGMGEHTMALLGWTGDNGDPDNFLYVLLDKDNAVTPDAGNIAFYVNDEVH
DLLIRARQTTDQAERTRLYEEAQVKIMEDAPWVPLMHTRVPIAVRKGITGYVPNPTGSESLAKVSLP

Sequences:

>Translated_547_residues
MLSACGSSSPSGTDGGSQSGGQTDTTPSTQDGGSTTPAPQQPAAQEKVLVWGRGGDSVSLDPIQVTDGESLKVTHQIYEG
LLDYAPGSTEVVPVLATEWEASPDGLEWTFKLRQGVKFHDGTDFNAEAVKINFDRWRNTSDPLHVGGEFPYYSYMFGGFD
EASNIQDVIVVDDYTVKFVLKNIQASFLQDIAMVPFAIASPKALQENPERLNDHPVGTGPFRFVSWTKGDRIVLEANPDY
WGGKPAIDRLIYRSIPDNNARLVALQAGELDVMDGVEPAFLPTIQATGQFDIIERPPMNIGYLAFNTQKPPFDNVLIRRA
INHAINKEELNTAFYGGMGIPAVSPLPPSVWGHNPNVPKYEYDPEKAKELLAQAGYGPDNPLKTELWAMPVPRPYMPQPE
RIGVAIQNYLREVGIEAEIVTYEWGTYLEKTGMGEHTMALLGWTGDNGDPDNFLYVLLDKDNAVTPDAGNIAFYVNDEVH
DLLIRARQTTDQAERTRLYEEAQVKIMEDAPWVPLMHTRVPIAVRKGITGYVPNPTGSESLAKVSLP
>Mature_547_residues
MLSACGSSSPSGTDGGSQSGGQTDTTPSTQDGGSTTPAPQQPAAQEKVLVWGRGGDSVSLDPIQVTDGESLKVTHQIYEG
LLDYAPGSTEVVPVLATEWEASPDGLEWTFKLRQGVKFHDGTDFNAEAVKINFDRWRNTSDPLHVGGEFPYYSYMFGGFD
EASNIQDVIVVDDYTVKFVLKNIQASFLQDIAMVPFAIASPKALQENPERLNDHPVGTGPFRFVSWTKGDRIVLEANPDY
WGGKPAIDRLIYRSIPDNNARLVALQAGELDVMDGVEPAFLPTIQATGQFDIIERPPMNIGYLAFNTQKPPFDNVLIRRA
INHAINKEELNTAFYGGMGIPAVSPLPPSVWGHNPNVPKYEYDPEKAKELLAQAGYGPDNPLKTELWAMPVPRPYMPQPE
RIGVAIQNYLREVGIEAEIVTYEWGTYLEKTGMGEHTMALLGWTGDNGDPDNFLYVLLDKDNAVTPDAGNIAFYVNDEVH
DLLIRARQTTDQAERTRLYEEAQVKIMEDAPWVPLMHTRVPIAVRKGITGYVPNPTGSESLAKVSLP

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=518, Percent_Identity=39.7683397683398, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1787052, Length=491, Percent_Identity=32.7902240325866, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI1787762, Length=502, Percent_Identity=31.2749003984064, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1787551, Length=531, Percent_Identity=30.1318267419962, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787495, Length=513, Percent_Identity=26.3157894736842, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789887, Length=478, Percent_Identity=29.4979079497908, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1789397, Length=503, Percent_Identity=25.844930417495, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081878, Length=518, Percent_Identity=24.9034749034749, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60182; Mature: 60182

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSACGSSSPSGTDGGSQSGGQTDTTPSTQDGGSTTPAPQQPAAQEKVLVWGRGGDSVSL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEC
DPIQVTDGESLKVTHQIYEGLLDYAPGSTEVVPVLATEWEASPDGLEWTFKLRQGVKFHD
CCEEECCCCCEEEHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCEECC
GTDFNAEAVKINFDRWRNTSDPLHVGGEFPYYSYMFGGFDEASNIQDVIVVDDYTVKFVL
CCCCCCEEEEEEHHHCCCCCCCEEECCCCCCHHHEECCCCCCCCCCEEEEECCCCHHHHH
KNIQASFLQDIAMVPFAIASPKALQENPERLNDHPVGTGPFRFVSWTKGDRIVLEANPDY
HHHHHHHHHHHHHCCEECCCCHHHHCCCHHHCCCCCCCCCEEEEEECCCCEEEEECCCCC
WGGKPAIDRLIYRSIPDNNARLVALQAGELDVMDGVEPAFLPTIQATGQFDIIERPPMNI
CCCCHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCCCCCEEECCCCEEEEECCCCCE
GYLAFNTQKPPFDNVLIRRAINHAINKEELNTAFYGGMGIPAVSPLPPSVWGHNPNVPKY
EEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCCCCCCCHHCCCCCCCCCC
EYDPEKAKELLAQAGYGPDNPLKTELWAMPVPRPYMPQPERIGVAIQNYLREVGIEAEIV
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
TYEWGTYLEKTGMGEHTMALLGWTGDNGDPDNFLYVLLDKDNAVTPDAGNIAFYVNDEVH
EEECCCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHH
DLLIRARQTTDQAERTRLYEEAQVKIMEDAPWVPLMHTRVPIAVRKGITGYVPNPTGSES
HHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCCEEEECCCCEEECCCCCCCCCCCCCCCC
LAKVSLP
EEEECCC
>Mature Secondary Structure
MLSACGSSSPSGTDGGSQSGGQTDTTPSTQDGGSTTPAPQQPAAQEKVLVWGRGGDSVSL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEC
DPIQVTDGESLKVTHQIYEGLLDYAPGSTEVVPVLATEWEASPDGLEWTFKLRQGVKFHD
CCEEECCCCCEEEHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCEECC
GTDFNAEAVKINFDRWRNTSDPLHVGGEFPYYSYMFGGFDEASNIQDVIVVDDYTVKFVL
CCCCCCEEEEEEHHHCCCCCCCEEECCCCCCHHHEECCCCCCCCCCEEEEECCCCHHHHH
KNIQASFLQDIAMVPFAIASPKALQENPERLNDHPVGTGPFRFVSWTKGDRIVLEANPDY
HHHHHHHHHHHHHCCEECCCCHHHHCCCHHHCCCCCCCCCEEEEEECCCCEEEEECCCCC
WGGKPAIDRLIYRSIPDNNARLVALQAGELDVMDGVEPAFLPTIQATGQFDIIERPPMNI
CCCCHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCCCCCEEECCCCEEEEECCCCCE
GYLAFNTQKPPFDNVLIRRAINHAINKEELNTAFYGGMGIPAVSPLPPSVWGHNPNVPKY
EEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCCCCCCCHHCCCCCCCCCC
EYDPEKAKELLAQAGYGPDNPLKTELWAMPVPRPYMPQPERIGVAIQNYLREVGIEAEIV
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
TYEWGTYLEKTGMGEHTMALLGWTGDNGDPDNFLYVLLDKDNAVTPDAGNIAFYVNDEVH
EEECCCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHH
DLLIRARQTTDQAERTRLYEEAQVKIMEDAPWVPLMHTRVPIAVRKGITGYVPNPTGSES
HHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCCEEEECCCCEEECCCCCCCCCCCCCCCC
LAKVSLP
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]