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The map label for this gene is licR [H]

Identifier: 51893450

GI number: 51893450

Start: 2495943

End: 2497847

Strand: Reverse

Name: licR [H]

Synonym: STH2312

Alternate gene names: 51893450

Gene position: 2497847-2495943 (Counterclockwise)

Preceding gene: 51893451

Following gene: 51893449

Centisome position: 70.04

GC content: 73.96

Gene sequence:

>1905_bases
TTGGGTTACCCCGCGCGCTCCGTCCGTTACGACCTGGAGCTGCTCTGCGACTGGGTGGCGGCCCACGGCGCGCGCCTGGT
CAGCACGGCCGGCGTCGGCTACCACCTGGAGGGGGACACCGACCGGGTCCGCCGGCACCTGGACCGGCTCATGACCGGCG
GGCCGCCGCCCAGCGAGTACATCCCCTCGCCGCGGGAGCGAATCCGCCGGCTCCTCCTCATGCTGCTCAGCGACGACGCG
CCGCGGCGGCTGAGCGTGCTCGCGGACCGGCTGGGGGTCGGCAAGTCCACGGTGCACACCGACCTGGCCACCGCGGAGTC
CTGGGCCTCCCGCCGCGGGCTGGCGCTGGCGCGCGGCCACGCGGGCATCTGCCTGCGGGGGGCCGAGCCCCACTGGCGCC
GGGCCATCGTGGACCTGGTCGGTGAGCTGGCCGACGAGGCCCAGCTGGCCATGCTGCTGGAAGAGCATCCCGACGCCGCA
CCGCTGCAGGCGCTCCTGCGGCCGCTGGTGCCCCGTGTGTCGTGGGGGCGGCTGGGCGACCTGCTGCGGGAGTTGGGCGC
GCCGGAGCTGTCCATCTGCGTGGCGGTGATGCTCAGCCGCCTGCAGGCCGGGCATACGCTGTCCTACAGCCCGGACCAGG
TCTCCCGGGGGCTGTCGTCGCCCTGGGGGCGGGAGGCCCAGGCCATCTGCCGGGCGCTGGAGTCCCGCTTCGGCGTCCGC
ATCCCCAACACCGAGGCGGCCTGGCTTGCCCTGCAGCTGGAGGCGACCCGGGCAGTGAACCCGGCGCCGGGCAGGGACAT
CGTGCACCCGGCGGACCTGGAGCTGGCGGAGCAGATGGCCGTCCTGGTGGAGACCCGGCTGGGCATCGGCCTGCGGCAGG
ACCGGGAGTTCCTGATGGGGCTGGCGCTGCACCTCCGGCCCATCGCCGAGCGGCTGCGACGGGGCGAGGCGGTGGAGAAC
CCGCTGCTGGACGAGGTGCAGGCCAAGTACCCGGCCGCGTGCCTGGCCGCGCAGGACGTGGGGCGCGCGCTCTCCGCCAT
CTGGGGGCTGACGGTGCCCGAGCCGGAGATCGGCTACCTGGCCATCCACATCGCCGCCGCCCTGGAGCGGGAGAAGCTGC
GCCGCCGGACCGTTCCCCGCGCGCTCATCGTGTGCAGCTCGGGCGTCGGCACCTCCGCCCTGCTGGTGACCCGGATCCGG
TCGCTGCTGCCGGAGATTCAGCCGGGCCGCGTCGTCTCGGCCTTCCGGGTGCGGGAGGTGCTGGCGGAGGATCCCCACGA
CCTGGTCGTCGCCACCTGCCAGGTGCCCCCCTGCGGGCTGCCGGTGGTGCGGGTCTCGCCGCTTCTGGGGGAGGACGACG
TCGCCAGGGTCCGCCGCACGGTCATGGCGCTGCAATCTGAGGCATGGAGAGGTAGACAGCCCGTGTTGAGTGAGTTGCTG
ACCGCGGAGACGATCGCCCTGGACGTGGACGCGCAGAACTGGGAGGAGGCCATCCGGGCGGGGGGCGACCTGCTGGTGAG
GGCCGGCCTGGCCGAGCCGCGCTACGTGGACGCCATGGTCCGGACGGCCCGGGAGTATGGTCCCTACATCGTGCTGGGTC
CGGGCTTCGCCCTGCCCCACGCCCGGCCGGGCGACGGCGTGCTCCGGCTGGGCATGTCGCTGGTCCGGCTGCGGAAGCCG
GTGCCCTTCGGCCACCCCGACAACGATCCGGTCCGGCTGGTGGTCTGCCTCGGGGCGATCGACAACGAGACCCACCTGAA
GGCCCTGATGGAGCTGTCCGAACTGCTCGCGAACCCGCAGTCGGTGGAGGCGCTGCACACCGCCGCCGACGTGGCGGAAG
TGCTCCGGCTGATCCGGTCGGTCTCGGCGCCCCCGTCGGAACCCGGCGAAGGGGAGGTGACCTAG

Upstream 100 bases:

>100_bases
AGGGAGGCGAGGGCCCGTGCTCAACGACCGGCGCGAGCGGTTGCTGCGGCTGCTCCTGGCGGCCAACGGACCGCTTCCGG
CCGCGGAGATCGGCCGGCTG

Downstream 100 bases:

>100_bases
GTGACTGCGCCGGACGTTCCGCTGCTCACCGAGATCGCGAAGCGCATCCGCGTCCACGTGATCCGCACCGTCCTGCGCCT
GGGGAGCGGCCACCTGGGCG

Product: putative PTS system, IIA component

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MGYPARSVRYDLELLCDWVAAHGARLVSTAGVGYHLEGDTDRVRRHLDRLMTGGPPPSEYIPSPRERIRRLLLMLLSDDA
PRRLSVLADRLGVGKSTVHTDLATAESWASRRGLALARGHAGICLRGAEPHWRRAIVDLVGELADEAQLAMLLEEHPDAA
PLQALLRPLVPRVSWGRLGDLLRELGAPELSICVAVMLSRLQAGHTLSYSPDQVSRGLSSPWGREAQAICRALESRFGVR
IPNTEAAWLALQLEATRAVNPAPGRDIVHPADLELAEQMAVLVETRLGIGLRQDREFLMGLALHLRPIAERLRRGEAVEN
PLLDEVQAKYPAACLAAQDVGRALSAIWGLTVPEPEIGYLAIHIAAALEREKLRRRTVPRALIVCSSGVGTSALLVTRIR
SLLPEIQPGRVVSAFRVREVLAEDPHDLVVATCQVPPCGLPVVRVSPLLGEDDVARVRRTVMALQSEAWRGRQPVLSELL
TAETIALDVDAQNWEEAIRAGGDLLVRAGLAEPRYVDAMVRTAREYGPYIVLGPGFALPHARPGDGVLRLGMSLVRLRKP
VPFGHPDNDPVRLVVCLGAIDNETHLKALMELSELLANPQSVEALHTAADVAEVLRLIRSVSAPPSEPGEGEVT

Sequences:

>Translated_634_residues
MGYPARSVRYDLELLCDWVAAHGARLVSTAGVGYHLEGDTDRVRRHLDRLMTGGPPPSEYIPSPRERIRRLLLMLLSDDA
PRRLSVLADRLGVGKSTVHTDLATAESWASRRGLALARGHAGICLRGAEPHWRRAIVDLVGELADEAQLAMLLEEHPDAA
PLQALLRPLVPRVSWGRLGDLLRELGAPELSICVAVMLSRLQAGHTLSYSPDQVSRGLSSPWGREAQAICRALESRFGVR
IPNTEAAWLALQLEATRAVNPAPGRDIVHPADLELAEQMAVLVETRLGIGLRQDREFLMGLALHLRPIAERLRRGEAVEN
PLLDEVQAKYPAACLAAQDVGRALSAIWGLTVPEPEIGYLAIHIAAALEREKLRRRTVPRALIVCSSGVGTSALLVTRIR
SLLPEIQPGRVVSAFRVREVLAEDPHDLVVATCQVPPCGLPVVRVSPLLGEDDVARVRRTVMALQSEAWRGRQPVLSELL
TAETIALDVDAQNWEEAIRAGGDLLVRAGLAEPRYVDAMVRTAREYGPYIVLGPGFALPHARPGDGVLRLGMSLVRLRKP
VPFGHPDNDPVRLVVCLGAIDNETHLKALMELSELLANPQSVEALHTAADVAEVLRLIRSVSAPPSEPGEGEVT
>Mature_633_residues
GYPARSVRYDLELLCDWVAAHGARLVSTAGVGYHLEGDTDRVRRHLDRLMTGGPPPSEYIPSPRERIRRLLLMLLSDDAP
RRLSVLADRLGVGKSTVHTDLATAESWASRRGLALARGHAGICLRGAEPHWRRAIVDLVGELADEAQLAMLLEEHPDAAP
LQALLRPLVPRVSWGRLGDLLRELGAPELSICVAVMLSRLQAGHTLSYSPDQVSRGLSSPWGREAQAICRALESRFGVRI
PNTEAAWLALQLEATRAVNPAPGRDIVHPADLELAEQMAVLVETRLGIGLRQDREFLMGLALHLRPIAERLRRGEAVENP
LLDEVQAKYPAACLAAQDVGRALSAIWGLTVPEPEIGYLAIHIAAALEREKLRRRTVPRALIVCSSGVGTSALLVTRIRS
LLPEIQPGRVVSAFRVREVLAEDPHDLVVATCQVPPCGLPVVRVSPLLGEDDVARVRRTVMALQSEAWRGRQPVLSELLT
AETIALDVDAQNWEEAIRAGGDLLVRAGLAEPRYVDAMVRTAREYGPYIVLGPGFALPHARPGDGVLRLGMSLVRLRKPV
PFGHPDNDPVRLVVCLGAIDNETHLKALMELSELLANPQSVEALHTAADVAEVLRLIRSVSAPPSEPGEGEVT

Specific function: Positive regulator of the licABCH operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367359, Length=146, Percent_Identity=39.7260273972603, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1790755, Length=128, Percent_Identity=34.375, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1789302, Length=115, Percent_Identity=36.5217391304348, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790027, Length=141, Percent_Identity=36.1702127659575, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 69030; Mature: 68899

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYPARSVRYDLELLCDWVAAHGARLVSTAGVGYHLEGDTDRVRRHLDRLMTGGPPPSEY
CCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCC
IPSPRERIRRLLLMLLSDDAPRRLSVLADRLGVGKSTVHTDLATAESWASRRGLALARGH
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCC
AGICLRGAEPHWRRAIVDLVGELADEAQLAMLLEEHPDAAPLQALLRPLVPRVSWGRLGD
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
LLRELGAPELSICVAVMLSRLQAGHTLSYSPDQVSRGLSSPWGREAQAICRALESRFGVR
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
IPNTEAAWLALQLEATRAVNPAPGRDIVHPADLELAEQMAVLVETRLGIGLRQDREFLMG
CCCCCCEEEEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LALHLRPIAERLRRGEAVENPLLDEVQAKYPAACLAAQDVGRALSAIWGLTVPEPEIGYL
HHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AIHIAAALEREKLRRRTVPRALIVCSSGVGTSALLVTRIRSLLPEIQPGRVVSAFRVREV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LAEDPHDLVVATCQVPPCGLPVVRVSPLLGEDDVARVRRTVMALQSEAWRGRQPVLSELL
HHCCCCCEEEEEECCCCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TAETIALDVDAQNWEEAIRAGGDLLVRAGLAEPRYVDAMVRTAREYGPYIVLGPGFALPH
HHHHHEEECCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCC
ARPGDGVLRLGMSLVRLRKPVPFGHPDNDPVRLVVCLGAIDNETHLKALMELSELLANPQ
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCH
SVEALHTAADVAEVLRLIRSVSAPPSEPGEGEVT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GYPARSVRYDLELLCDWVAAHGARLVSTAGVGYHLEGDTDRVRRHLDRLMTGGPPPSEY
CCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCCCCCCC
IPSPRERIRRLLLMLLSDDAPRRLSVLADRLGVGKSTVHTDLATAESWASRRGLALARGH
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCC
AGICLRGAEPHWRRAIVDLVGELADEAQLAMLLEEHPDAAPLQALLRPLVPRVSWGRLGD
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
LLRELGAPELSICVAVMLSRLQAGHTLSYSPDQVSRGLSSPWGREAQAICRALESRFGVR
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
IPNTEAAWLALQLEATRAVNPAPGRDIVHPADLELAEQMAVLVETRLGIGLRQDREFLMG
CCCCCCEEEEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LALHLRPIAERLRRGEAVENPLLDEVQAKYPAACLAAQDVGRALSAIWGLTVPEPEIGYL
HHHHHHHHHHHHHCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
AIHIAAALEREKLRRRTVPRALIVCSSGVGTSALLVTRIRSLLPEIQPGRVVSAFRVREV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LAEDPHDLVVATCQVPPCGLPVVRVSPLLGEDDVARVRRTVMALQSEAWRGRQPVLSELL
HHCCCCCEEEEEECCCCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TAETIALDVDAQNWEEAIRAGGDLLVRAGLAEPRYVDAMVRTAREYGPYIVLGPGFALPH
HHHHHEEECCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCC
ARPGDGVLRLGMSLVRLRKPVPFGHPDNDPVRLVVCLGAIDNETHLKALMELSELLANPQ
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCH
SVEALHTAADVAEVLRLIRSVSAPPSEPGEGEVT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377; 10438772 [H]