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The map label for this gene is yprA [H]

Identifier: 51893431

GI number: 51893431

Start: 2471980

End: 2474676

Strand: Reverse

Name: yprA [H]

Synonym: STH2293

Alternate gene names: 51893431

Gene position: 2474676-2471980 (Counterclockwise)

Preceding gene: 51893432

Following gene: 51893428

Centisome position: 69.39

GC content: 66.96

Gene sequence:

>2697_bases
GTGGGTGCCGTGATCACATCCGTCTTGCAGCGCCTCGGCTGGTCGCTGGAGCATCAGCAGCTGCTGCCGGGGCGGGAACC
GGAGTTCTATTCCGTCGCCGACCTGCCGTTGCGACCGGAGACGCACCGGCTGCTTGACCGGTATCCGCAGGGCGTATACC
GCCACCAACGGCTTGCCCTGGAGTCCTATCTGGAGGGGAAGGACCTGTGCGTGGCTACCAGCACCGCCTCCGGGAAGAGC
CTGGTTTTCTACGCCACCGGCGTCGAATGTCTGGCGGCGGACCCGAGTGCGCGCATCCTGGCCATCTACCCGCTGAAGGC
CCTGGCCCGGGAGCAGGAGTCCCGCTGGCAGAAGGAACTGGAGTCGGCAGGCATCGTGGCCAGCGTCGGCCGCATCGACG
GCGGGGTGAAGGACCGCCAGCAGCGGGAGCGCATCCTTGCATCCAGCCGGGTCGTGCTCATGACCCCCGACATCATCCAC
GCCTGGTTGCTCAGCAGCCTTTCTGCACGCCGAGTCCAGCGATTCCTGGCCTCCCTGCGGCTGGTGATCGTGGACGAGGT
GCACGTATACACCGGGGTCTTTGGCTCCAACGCCGCCTACGTCTTCCGGCGACTGCAGCACGCCGCGCGGACCCTAGCTG
GTGGCGACCGGCTCCAGTTCGTGGCGGCGTCGGCTACCGTCGCCAACCCCGAGCAGCACCTCGCTCAGCTCTTCGGCCGG
ACAGTGCAGGTCATCGGCGACCAAGCCGACACCTCGCCCCGGCACGAGCGGCAGCTTTACCTGGTGCGTCCGCCGGCTGG
CCAGGCCCTGTATACCGCCCTGCCGCACCTCCTGCGGGCCGTTGTGGACGACACCCCTTACCGATTCCTCACTTTTGTCG
ACAGCCGCCGCCAGACCGAGCAGTTGGCCACCATCCTGGCCCGGGCCCGGTTCAACAGGCCGGAAGAGGACCCGGCTTAT
GGGGACGGGGTAGACGACGGTGATCTGGAGGGCAGCGGGCCGGAGGCTGAGCGGGAGGGCGATGCCGCCCTTGCCGATCG
GCTGCTGGAACGGCTGCCGGTGCTCCCCTACCGCTCCGGGTACGAGGAGACCGACCGGGAGGCGATCCAGTCTCGTCTGA
GCGAGGGCACCCTGCGGGGCATCATCAGTACGAGCGCCTTGGAACTGGGGCTGGACATTCAGGGGCTGGATATGGTCATC
CTCGTGGGCATTCCTCAGACGGTCACAAGCCTGCAGCAGCGTATCGGCCGGGTGGGTCGGCACGGCCCCGGCAGCATCGT
CCTGATCGACGCAGGCGGTCTTGCCGACGAACTGGTCTTCAACGAGCCCGAGCGCCTGTTTGACCGACCGCTCCTGCCGG
CCGTCCTCCACCTGGAGAACCGCCGGATCCAGTATATCCATGCCCTGTGCTTCGCCAGCCGGGGCGGTGAGTACGACACC
CTGACGGGTGCGGACGTCGAAGGGGAGGGCGACATTGCCCTGCGGGTGACCGGTTCGTGGCCTCCTGGGTTCCTGGAGCT
CTGCCAGGCCGAGCGGGCCGGACAGGTGCCGCTGGATTTGCACAACCTGAAGGCCGACGGCGGGGACGACCCATGGCACG
CCTTTCCCCTCAGGGACGTCGGCGTCCAGTATACGGTAGAGCAGCGCACCGGTGACCTCGTCCGGCTCGGCTCGCTGTCC
AGTGCCCAGCTGATGCGGGAGGGTTATCCCGGGGCGGTGTACTACTACCTCACCCGTCCCTACCGGGTCGTGAGGGTCTC
CCAGCGGGAGAAGAAAGTGCTGGTGCGGCGGGAGCGCTATTACACCACCGATCCCTACGGCCCGCTCGTCCTGATCTCGC
CTCAACTGACCCCTGAGGGCCTGCATCGCGCCGTGCGCATGGGCGAACTCCGGGCGGTGGAATGTGAACTGTACGTGTCA
GAGCGGGTATTCGGATATACCGAGCGGCGGGGCGGGAACAAGATGCCGCCCGTTAAGTACCCCTGTGAGTACTGGCACCT
GGCTAGCTTCAGCCGAAACTACACCAGCACCGGCGTGATCCTGAGCCACCCGGCGCTCTCCAACTCTGGCGTCCAGTTGA
AGCTGCTTGCAGACCTGCTGTTGGAGGCCTTCCTGCTGGTCGTGCCGTTTGAGCGCAGCGAGGTCAACAGTAGCACCGGA
AAGCACTGGAAGACCCAGAACGGGTTTGGGGAGGGGGAGCCCTTCCTGGCGATCTATGACCAGACCTACGGCAGCCTGCG
CCTGACCGGCCGGCTGCTGGAGCCGGCCGTCCTGCCCGAAGTGCTGACGGAGGCGTTGCATGTCCTCCGCAGCGGGCGGG
TCGAGGCGGTTGAAGGGATCTCCGAGGCCACCGTGCAGGCGCTGCAAGCGCTGGCCCAGGACTGCGCGGGCCAAGCAGAG
CCGTTGGAGCTGTTTTCCAGCGCACCGGAGCGGACGGGCGAACTGGAGGGGGAACCGGTCATCGCCCCCGGCAGCGTGGG
TTGGATCATCACCGACGACAACCAGGAGTTTCAGATCCAGCGCGTCTTCTACCATCCGAGGGAGGGGCTCCGGTACTACG
GCCGGCGCCTGGGCCAGCAAGAGCAGCCGGACGTGCAGGTCTGGTTCCCGGTGACCAACATCCGGCCGATTCCGGGCATC
AGCCGCATGGGGATCTACGACTACGAGACGGGCGAGGTCCGGCCGCTGGACGAGTGA

Upstream 100 bases:

>100_bases
GACACTATGCTGTCACTCGCCTCCCTTACTCTGGGAGACGTCAGGTGACTTTTCCCCGTCTCCCCGTCCGGTGGGTGCGG
GAATGCACGAAGAGTAAGGG

Downstream 100 bases:

>100_bases
CGCGCAAACGGTGCCCTGATGGGTCAGGGCACCGTTTGCGGCGTGTTGCGCTCATGCGAACCGGGTGTGGCCGGCCAGCT
TCGCCCGCTCCAGCATCTGC

Product: ATP-dependent helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MGAVITSVLQRLGWSLEHQQLLPGREPEFYSVADLPLRPETHRLLDRYPQGVYRHQRLALESYLEGKDLCVATSTASGKS
LVFYATGVECLAADPSARILAIYPLKALAREQESRWQKELESAGIVASVGRIDGGVKDRQQRERILASSRVVLMTPDIIH
AWLLSSLSARRVQRFLASLRLVIVDEVHVYTGVFGSNAAYVFRRLQHAARTLAGGDRLQFVAASATVANPEQHLAQLFGR
TVQVIGDQADTSPRHERQLYLVRPPAGQALYTALPHLLRAVVDDTPYRFLTFVDSRRQTEQLATILARARFNRPEEDPAY
GDGVDDGDLEGSGPEAEREGDAALADRLLERLPVLPYRSGYEETDREAIQSRLSEGTLRGIISTSALELGLDIQGLDMVI
LVGIPQTVTSLQQRIGRVGRHGPGSIVLIDAGGLADELVFNEPERLFDRPLLPAVLHLENRRIQYIHALCFASRGGEYDT
LTGADVEGEGDIALRVTGSWPPGFLELCQAERAGQVPLDLHNLKADGGDDPWHAFPLRDVGVQYTVEQRTGDLVRLGSLS
SAQLMREGYPGAVYYYLTRPYRVVRVSQREKKVLVRRERYYTTDPYGPLVLISPQLTPEGLHRAVRMGELRAVECELYVS
ERVFGYTERRGGNKMPPVKYPCEYWHLASFSRNYTSTGVILSHPALSNSGVQLKLLADLLLEAFLLVVPFERSEVNSSTG
KHWKTQNGFGEGEPFLAIYDQTYGSLRLTGRLLEPAVLPEVLTEALHVLRSGRVEAVEGISEATVQALQALAQDCAGQAE
PLELFSSAPERTGELEGEPVIAPGSVGWIITDDNQEFQIQRVFYHPREGLRYYGRRLGQQEQPDVQVWFPVTNIRPIPGI
SRMGIYDYETGEVRPLDE

Sequences:

>Translated_898_residues
MGAVITSVLQRLGWSLEHQQLLPGREPEFYSVADLPLRPETHRLLDRYPQGVYRHQRLALESYLEGKDLCVATSTASGKS
LVFYATGVECLAADPSARILAIYPLKALAREQESRWQKELESAGIVASVGRIDGGVKDRQQRERILASSRVVLMTPDIIH
AWLLSSLSARRVQRFLASLRLVIVDEVHVYTGVFGSNAAYVFRRLQHAARTLAGGDRLQFVAASATVANPEQHLAQLFGR
TVQVIGDQADTSPRHERQLYLVRPPAGQALYTALPHLLRAVVDDTPYRFLTFVDSRRQTEQLATILARARFNRPEEDPAY
GDGVDDGDLEGSGPEAEREGDAALADRLLERLPVLPYRSGYEETDREAIQSRLSEGTLRGIISTSALELGLDIQGLDMVI
LVGIPQTVTSLQQRIGRVGRHGPGSIVLIDAGGLADELVFNEPERLFDRPLLPAVLHLENRRIQYIHALCFASRGGEYDT
LTGADVEGEGDIALRVTGSWPPGFLELCQAERAGQVPLDLHNLKADGGDDPWHAFPLRDVGVQYTVEQRTGDLVRLGSLS
SAQLMREGYPGAVYYYLTRPYRVVRVSQREKKVLVRRERYYTTDPYGPLVLISPQLTPEGLHRAVRMGELRAVECELYVS
ERVFGYTERRGGNKMPPVKYPCEYWHLASFSRNYTSTGVILSHPALSNSGVQLKLLADLLLEAFLLVVPFERSEVNSSTG
KHWKTQNGFGEGEPFLAIYDQTYGSLRLTGRLLEPAVLPEVLTEALHVLRSGRVEAVEGISEATVQALQALAQDCAGQAE
PLELFSSAPERTGELEGEPVIAPGSVGWIITDDNQEFQIQRVFYHPREGLRYYGRRLGQQEQPDVQVWFPVTNIRPIPGI
SRMGIYDYETGEVRPLDE
>Mature_897_residues
GAVITSVLQRLGWSLEHQQLLPGREPEFYSVADLPLRPETHRLLDRYPQGVYRHQRLALESYLEGKDLCVATSTASGKSL
VFYATGVECLAADPSARILAIYPLKALAREQESRWQKELESAGIVASVGRIDGGVKDRQQRERILASSRVVLMTPDIIHA
WLLSSLSARRVQRFLASLRLVIVDEVHVYTGVFGSNAAYVFRRLQHAARTLAGGDRLQFVAASATVANPEQHLAQLFGRT
VQVIGDQADTSPRHERQLYLVRPPAGQALYTALPHLLRAVVDDTPYRFLTFVDSRRQTEQLATILARARFNRPEEDPAYG
DGVDDGDLEGSGPEAEREGDAALADRLLERLPVLPYRSGYEETDREAIQSRLSEGTLRGIISTSALELGLDIQGLDMVIL
VGIPQTVTSLQQRIGRVGRHGPGSIVLIDAGGLADELVFNEPERLFDRPLLPAVLHLENRRIQYIHALCFASRGGEYDTL
TGADVEGEGDIALRVTGSWPPGFLELCQAERAGQVPLDLHNLKADGGDDPWHAFPLRDVGVQYTVEQRTGDLVRLGSLSS
AQLMREGYPGAVYYYLTRPYRVVRVSQREKKVLVRRERYYTTDPYGPLVLISPQLTPEGLHRAVRMGELRAVECELYVSE
RVFGYTERRGGNKMPPVKYPCEYWHLASFSRNYTSTGVILSHPALSNSGVQLKLLADLLLEAFLLVVPFERSEVNSSTGK
HWKTQNGFGEGEPFLAIYDQTYGSLRLTGRLLEPAVLPEVLTEALHVLRSGRVEAVEGISEATVQALQALAQDCAGQAEP
LELFSSAPERTGELEGEPVIAPGSVGWIITDDNQEFQIQRVFYHPREGLRYYGRRLGQQEQPDVQVWFPVTNIRPIPGIS
RMGIYDYETGEVRPLDE

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=389, Percent_Identity=26.7352185089974, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320497, Length=467, Percent_Identity=29.1220556745182, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 99968; Mature: 99836

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAVITSVLQRLGWSLEHQQLLPGREPEFYSVADLPLRPETHRLLDRYPQGVYRHQRLAL
CCHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHH
ESYLEGKDLCVATSTASGKSLVFYATGVECLAADPSARILAIYPLKALAREQESRWQKEL
HHHCCCCCEEEEECCCCCCEEEEEECCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHH
ESAGIVASVGRIDGGVKDRQQRERILASSRVVLMTPDIIHAWLLSSLSARRVQRFLASLR
HHCCCEEEHHHCCCCCCHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHE
LVIVDEVHVYTGVFGSNAAYVFRRLQHAARTLAGGDRLQFVAASATVANPEQHLAQLFGR
EHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
TVQVIGDQADTSPRHERQLYLVRPPAGQALYTALPHLLRAVVDDTPYRFLTFVDSRRQTE
HEEHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
QLATILARARFNRPEEDPAYGDGVDDGDLEGSGPEAEREGDAALADRLLERLPVLPYRSG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
YEETDREAIQSRLSEGTLRGIISTSALELGLDIQGLDMVILVGIPQTVTSLQQRIGRVGR
CCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCC
HGPGSIVLIDAGGLADELVFNEPERLFDRPLLPAVLHLENRRIQYIHALCFASRGGEYDT
CCCCCEEEEECCCCHHHHHCCCCHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
LTGADVEGEGDIALRVTGSWPPGFLELCQAERAGQVPLDLHNLKADGGDDPWHAFPLRDV
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEECCHHHC
GVQYTVEQRTGDLVRLGSLSSAQLMREGYPGAVYYYLTRPYRVVRVSQREKKVLVRRERY
CEEEEEECCCCCEEEECCCCHHHHHHCCCCCEEEEEEECCEEEEEECCHHHHHHHHHHHC
YTTDPYGPLVLISPQLTPEGLHRAVRMGELRAVECELYVSERVFGYTERRGGNKMPPVKY
CCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEEEHHHHHCCHHHCCCCCCCCCCC
PCEYWHLASFSRNYTSTGVILSHPALSNSGVQLKLLADLLLEAFLLVVPFERSEVNSSTG
CCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCC
KHWKTQNGFGEGEPFLAIYDQTYGSLRLTGRLLEPAVLPEVLTEALHVLRSGRVEAVEGI
CCCCCCCCCCCCCCEEEEEECCCCCEEEECHHCCHHHHHHHHHHHHHHHHCCCHHHHHHH
SEATVQALQALAQDCAGQAEPLELFSSAPERTGELEGEPVIAPGSVGWIITDDNQEFQIQ
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCCCEEEE
RVFYHPREGLRYYGRRLGQQEQPDVQVWFPVTNIRPIPGISRMGIYDYETGEVRPLDE
EEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
GAVITSVLQRLGWSLEHQQLLPGREPEFYSVADLPLRPETHRLLDRYPQGVYRHQRLAL
CHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHH
ESYLEGKDLCVATSTASGKSLVFYATGVECLAADPSARILAIYPLKALAREQESRWQKEL
HHHCCCCCEEEEECCCCCCEEEEEECCCEEEECCCCCCEEEEECHHHHHHHHHHHHHHHH
ESAGIVASVGRIDGGVKDRQQRERILASSRVVLMTPDIIHAWLLSSLSARRVQRFLASLR
HHCCCEEEHHHCCCCCCHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHE
LVIVDEVHVYTGVFGSNAAYVFRRLQHAARTLAGGDRLQFVAASATVANPEQHLAQLFGR
EHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
TVQVIGDQADTSPRHERQLYLVRPPAGQALYTALPHLLRAVVDDTPYRFLTFVDSRRQTE
HEEHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
QLATILARARFNRPEEDPAYGDGVDDGDLEGSGPEAEREGDAALADRLLERLPVLPYRSG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
YEETDREAIQSRLSEGTLRGIISTSALELGLDIQGLDMVILVGIPQTVTSLQQRIGRVGR
CCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCC
HGPGSIVLIDAGGLADELVFNEPERLFDRPLLPAVLHLENRRIQYIHALCFASRGGEYDT
CCCCCEEEEECCCCHHHHHCCCCHHHHCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
LTGADVEGEGDIALRVTGSWPPGFLELCQAERAGQVPLDLHNLKADGGDDPWHAFPLRDV
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCEECCHHHC
GVQYTVEQRTGDLVRLGSLSSAQLMREGYPGAVYYYLTRPYRVVRVSQREKKVLVRRERY
CEEEEEECCCCCEEEECCCCHHHHHHCCCCCEEEEEEECCEEEEEECCHHHHHHHHHHHC
YTTDPYGPLVLISPQLTPEGLHRAVRMGELRAVECELYVSERVFGYTERRGGNKMPPVKY
CCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEEEEEHHHHHCCHHHCCCCCCCCCCC
PCEYWHLASFSRNYTSTGVILSHPALSNSGVQLKLLADLLLEAFLLVVPFERSEVNSSTG
CCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCC
KHWKTQNGFGEGEPFLAIYDQTYGSLRLTGRLLEPAVLPEVLTEALHVLRSGRVEAVEGI
CCCCCCCCCCCCCCEEEEEECCCCCEEEECHHCCHHHHHHHHHHHHHHHHCCCHHHHHHH
SEATVQALQALAQDCAGQAEPLELFSSAPERTGELEGEPVIAPGSVGWIITDDNQEFQIQ
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEECCCCEEEEEECCCCCEEEE
RVFYHPREGLRYYGRRLGQQEQPDVQVWFPVTNIRPIPGISRMGIYDYETGEVRPLDE
EEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]