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The map label for this gene is pdxA2 [H]

Identifier: 51893374

GI number: 51893374

Start: 2400243

End: 2400593

Strand: Reverse

Name: pdxA2 [H]

Synonym: STH2236

Alternate gene names: 51893374

Gene position: 2400593-2400243 (Counterclockwise)

Preceding gene: 51893375

Following gene: 51893373

Centisome position: 67.32

GC content: 70.94

Gene sequence:

>351_bases
GTGCACGTCTCGCTGCGGCAGGCGATCGACCTGGTCACCGCCGACCGGGGCAGGCGGGTAATCGGCGTCGCGCACCGCAC
TCTGCGGCGCATGGGCTTTCAGCACCCGCGCATCGCCGTGGCCGGCTTGAACCCGCACGCCGGCGAGAACGGACTGTTCG
GGGACGAGGAGATCCGGGAGATCGTTCCGGGCATCCAGGCCGCCCGGGAGGAGGGGTACGAGGCCACGGGGCCGTGGCCG
CCTGACACGGTCTTCGCCCGGGCGATGGCCGGCGAGTTCGACGCCGTCATCGCCATGTACCATGACCAGGGGCACATCCC
CATCAAGCTCGCCGGTTCGCCGAAGGCGTGA

Upstream 100 bases:

>100_bases
GCGACTCGTCAATCCTGGCGAACCGCCGGATGCGGACCCGCATGTCCGGTGGTGTGAGAGGACGGGGGTTAGCCGCCCCC
TCCTACTCGATTTCGTCACG

Downstream 100 bases:

>100_bases
ATGTGACCGCCGGCCTGCCGATCATCCGCACCTCCGTCGACCACGGCACCGCCTTCGACATCGCGGGCAAGGGCATTGCC
GACGAGGGCAGCATGATCGC

Product: pyridoxal phosphate biosynthetic protein variant

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase 2 [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MHVSLRQAIDLVTADRGRRVIGVAHRTLRRMGFQHPRIAVAGLNPHAGENGLFGDEEIREIVPGIQAAREEGYEATGPWP
PDTVFARAMAGEFDAVIAMYHDQGHIPIKLAGSPKA

Sequences:

>Translated_116_residues
MHVSLRQAIDLVTADRGRRVIGVAHRTLRRMGFQHPRIAVAGLNPHAGENGLFGDEEIREIVPGIQAAREEGYEATGPWP
PDTVFARAMAGEFDAVIAMYHDQGHIPIKLAGSPKA
>Mature_116_residues
MHVSLRQAIDLVTADRGRRVIGVAHRTLRRMGFQHPRIAVAGLNPHAGENGLFGDEEIREIVPGIQAAREEGYEATGPWP
PDTVFARAMAGEFDAVIAMYHDQGHIPIKLAGSPKA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=112, Percent_Identity=44.6428571428571, Blast_Score=93, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 12631; Mature: 12631

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVSLRQAIDLVTADRGRRVIGVAHRTLRRMGFQHPRIAVAGLNPHAGENGLFGDEEIRE
CCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHH
IVPGIQAAREEGYEATGPWPPDTVFARAMAGEFDAVIAMYHDQGHIPIKLAGSPKA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MHVSLRQAIDLVTADRGRRVIGVAHRTLRRMGFQHPRIAVAGLNPHAGENGLFGDEEIRE
CCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHH
IVPGIQAAREEGYEATGPWPPDTVFARAMAGEFDAVIAMYHDQGHIPIKLAGSPKA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]