Click here to switch to the map view.

The map label for this gene is serA [H]

Identifier: 51893370

GI number: 51893370

Start: 2398482

End: 2398904

Strand: Reverse

Name: serA [H]

Synonym: STH2232

Alternate gene names: 51893370

Gene position: 2398904-2398482 (Counterclockwise)

Preceding gene: 51893371

Following gene: 51893369

Centisome position: 67.27

GC content: 68.32

Gene sequence:

>423_bases
ATGGCGGACAGGATCAAGGTGCTCATGCTGCAAGCGATCCACGAAGAAGGGATCCTGCTCTTCGACGACCGGTTTGAGGT
GATCGCAGCCCGGGATCCCTCGCCCGCAGCGGTCATTCCGGAACTGGACGGGGTGCAGGCCATCATCGTCCGCCTCGCGC
CGTGCACGCGGGAGATCATCGAGGCGGCCCCTGACCTGAGGGTGATCGCCAAGCACGGCGTCGGCGTCGACAACATCGAT
GTCGCCGCGGCGACCGAGCGCGGCATCCTGGTGCTCAACACGCCGGAGGCCAACGCCGTCTCGGTGGCGGAGCACGCCAT
CGCCGCGATCGCGGCCCTGGCCAAGCGGGTGGTGTTCATGGACCGGGCCGTCCGGGACGGGCGGTGGCAGGCGCGCGGCG
ATCTGAAGGCCATCGACCTGTAA

Upstream 100 bases:

>100_bases
CGCGACGCGACGGCTCATGGACAACAACCCCCGCAACCTGACGGTTGAAGAGGTAGAGGCAATCTATCGCTCGGCCCTGT
GAAGGAGGAGCAGCCGGGAG

Downstream 100 bases:

>100_bases
GGCAAGGTGCTGGGGCTGGTGGGCATCGGCCGCATCGGCACTCAGGTTGCCCGGAAGGCGCAGGCCGCCTTCGACATGCA
GGTCATCGGCTACGACCCGT

Product: phosphoglycerate dehydrogenase

Products: NA

Alternate protein names: PGDH [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MADRIKVLMLQAIHEEGILLFDDRFEVIAARDPSPAAVIPELDGVQAIIVRLAPCTREIIEAAPDLRVIAKHGVGVDNID
VAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFMDRAVRDGRWQARGDLKAIDL

Sequences:

>Translated_140_residues
MADRIKVLMLQAIHEEGILLFDDRFEVIAARDPSPAAVIPELDGVQAIIVRLAPCTREIIEAAPDLRVIAKHGVGVDNID
VAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFMDRAVRDGRWQARGDLKAIDL
>Mature_139_residues
ADRIKVLMLQAIHEEGILLFDDRFEVIAARDPSPAAVIPELDGVQAIIVRLAPCTREIIEAAPDLRVIAKHGVGVDNIDV
AAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFMDRAVRDGRWQARGDLKAIDL

Specific function: Unknown

COG id: COG0111

COG function: function code HE; Phosphoglycerate dehydrogenase and related dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI23308577, Length=115, Percent_Identity=37.3913043478261, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17532191, Length=133, Percent_Identity=36.0902255639098, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19921140, Length=127, Percent_Identity=33.8582677165354, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR006236
- InterPro:   IPR006139
- InterPro:   IPR006140
- InterPro:   IPR015508
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00389 2-Hacid_dh; PF02826 2-Hacid_dh_C; PF01842 ACT [H]

EC number: =1.1.1.95 [H]

Molecular weight: Translated: 15061; Mature: 14930

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRIKVLMLQAIHEEGILLFDDRFEVIAARDPSPAAVIPELDGVQAIIVRLAPCTREII
CCCHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCEECCCCCCHHHHHHHHCHHHHHHH
EAAPDLRVIAKHGVGVDNIDVAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFM
HCCCCEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DRAVRDGRWQARGDLKAIDL
HHHHCCCCEECCCCEEEECC
>Mature Secondary Structure 
ADRIKVLMLQAIHEEGILLFDDRFEVIAARDPSPAAVIPELDGVQAIIVRLAPCTREII
CCHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCCEECCCCCCHHHHHHHHCHHHHHHH
EAAPDLRVIAKHGVGVDNIDVAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFM
HCCCCEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DRAVRDGRWQARGDLKAIDL
HHHHCCCCEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]