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The map label for this gene is hmeB [H]

Identifier: 51893220

GI number: 51893220

Start: 2218012

End: 2219286

Strand: Reverse

Name: hmeB [H]

Synonym: STH2082

Alternate gene names: 51893220

Gene position: 2219286-2218012 (Counterclockwise)

Preceding gene: 51893221

Following gene: 51893219

Centisome position: 62.23

GC content: 69.02

Gene sequence:

>1275_bases
ATGTCCGCACTGACCCGAGAAGAGGCGGCCCTGCGGCTCGCCGACCAGCGCCCGTCGCCCGGGCCGGGCAGGCTGCTCCG
AGCGGGCTGGTACCTGCTGCTCATCGCCCTGGTCGCCGCCGGCGGGGTAGCCATCGCCCACCGGACCGCGCACGGGCTTG
CCGCCACCAACCTGACCTCGATCACCCCCTGGGGCGCCTGGATTGCCTTCTACATCTACTTCGTCGGCCTCTCGGCCGGG
GCGTTCCTGCTTTCCAGCCTCATCTATGTGTTCGGCATGGCCCGGTTCGAGCGGCTGGGGCGGATGGCCCTGCTCACCGC
CCTGGTGGCGATGATCGTCGCCCTGACCTTCGTGCTGCTGGACCTGGGCCGGATGGAGCGGGCGCTCAGCGCCCTGGTCT
ACTTCAACTGGCTCTCGCCGCTCGCCTGGGAGATGCGCTTCTACGTGATCTACATCCTGCTCCTGGCCGCCGAGCTCTGG
TTCGCGATGCGCGCCGACCTGGTGCGCCGGGCGGAGCGTTCCCGACTGGCCCGGTGGCTCAGCTTCGGCAGCCGGTCCCT
GGACACCGGGCGGGATCACCGGATGCTCCGGATCCTCGGCACCATCGGCGTGCCCATCGCCATCTTCGGCGTGCACGGCG
GCACGGGCACGATCTTCGCCATCGTGAAGGCCCGGGGCATGTGGTTCTCGGCGCTCACGCCCATCGTGTTCATCGTGTCG
GCGCTGGTATCGGGCACGGCGCTCCTGGCCCTGCTCTACATCCTGCGGCAGAAGGCACTGAAGCGGCCCGTGAACGCCGG
CATGGTGGCGGACCTGGGCAAGCTGCTGGGCGGCTTCCTGCTGGTGGATCTGGGGCTCCTGTTCTACGAGTTCCTGGTGC
CGTTGCTCTCCATGGCGCCGCACGAGACCAGCGTCGTGCACCTGATGATGGAGGGGCCCTACGCCTGGACCTTCTGGATC
CTGCAGCTGGGCATCGGCATGGTAGCGCCGGCGATCCTCCTGATGACCCGCCTGCGGGAGTCCGTGCCGCTCACCGCCCT
GGCCTGCCTCATGGTGGTCGTGGGCATCGTGGGCGTGCGGTTCAACATCGTCGTGCCGCCGCTCATCGAGCCCGTGCTGC
AGGGGCTGCCCGCCGGCCAGTACTTCCCGAACGCGGTGGAGTGGTGGACGAGCGCTGGCATCATCGCCATGGGGCTCCTG
CTCTTCAGCGTGGCCGCGGACCTGCTGCCCGTGGATGAGGAAGTGCACGAGATCGGAGGGACGGCCCATGACTGA

Upstream 100 bases:

>100_bases
GTGGCCAAGCTGGCCGCCAGCCCGCGGGCCTTCCGGCTGAAGGAGGAGCTGGGCACGCAGCCCCGGGTCATCTACCTGAA
GTAGGAGGAGGGAACGCTCG

Downstream 100 bases:

>100_bases
GGATCGCAAGCACCGCCAGGCAGACTCTTCTTCGGCCCTCACCCGCCGTCAGTTCGTCGCCGGGGCGGCGGTGGTGGGCG
GTTCCATCGCCGCGATGCCC

Product: molybdopterin oxidoreductase membrane subunit

Products: NA

Alternate protein names: Hme subunit B [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSALTREEAALRLADQRPSPGPGRLLRAGWYLLLIALVAAGGVAIAHRTAHGLAATNLTSITPWGAWIAFYIYFVGLSAG
AFLLSSLIYVFGMARFERLGRMALLTALVAMIVALTFVLLDLGRMERALSALVYFNWLSPLAWEMRFYVIYILLLAAELW
FAMRADLVRRAERSRLARWLSFGSRSLDTGRDHRMLRILGTIGVPIAIFGVHGGTGTIFAIVKARGMWFSALTPIVFIVS
ALVSGTALLALLYILRQKALKRPVNAGMVADLGKLLGGFLLVDLGLLFYEFLVPLLSMAPHETSVVHLMMEGPYAWTFWI
LQLGIGMVAPAILLMTRLRESVPLTALACLMVVVGIVGVRFNIVVPPLIEPVLQGLPAGQYFPNAVEWWTSAGIIAMGLL
LFSVAADLLPVDEEVHEIGGTAHD

Sequences:

>Translated_424_residues
MSALTREEAALRLADQRPSPGPGRLLRAGWYLLLIALVAAGGVAIAHRTAHGLAATNLTSITPWGAWIAFYIYFVGLSAG
AFLLSSLIYVFGMARFERLGRMALLTALVAMIVALTFVLLDLGRMERALSALVYFNWLSPLAWEMRFYVIYILLLAAELW
FAMRADLVRRAERSRLARWLSFGSRSLDTGRDHRMLRILGTIGVPIAIFGVHGGTGTIFAIVKARGMWFSALTPIVFIVS
ALVSGTALLALLYILRQKALKRPVNAGMVADLGKLLGGFLLVDLGLLFYEFLVPLLSMAPHETSVVHLMMEGPYAWTFWI
LQLGIGMVAPAILLMTRLRESVPLTALACLMVVVGIVGVRFNIVVPPLIEPVLQGLPAGQYFPNAVEWWTSAGIIAMGLL
LFSVAADLLPVDEEVHEIGGTAHD
>Mature_423_residues
SALTREEAALRLADQRPSPGPGRLLRAGWYLLLIALVAAGGVAIAHRTAHGLAATNLTSITPWGAWIAFYIYFVGLSAGA
FLLSSLIYVFGMARFERLGRMALLTALVAMIVALTFVLLDLGRMERALSALVYFNWLSPLAWEMRFYVIYILLLAAELWF
AMRADLVRRAERSRLARWLSFGSRSLDTGRDHRMLRILGTIGVPIAIFGVHGGTGTIFAIVKARGMWFSALTPIVFIVSA
LVSGTALLALLYILRQKALKRPVNAGMVADLGKLLGGFLLVDLGLLFYEFLVPLLSMAPHETSVVHLMMEGPYAWTFWIL
QLGIGMVAPAILLMTRLRESVPLTALACLMVVVGIVGVRFNIVVPPLIEPVLQGLPAGQYFPNAVEWWTSAGIIAMGLLL
FSVAADLLPVDEEVHEIGGTAHD

Specific function: Has menaquinol-oxidizing activity. HmeB subunit may function as a menaquinol-oxidizing site. HmeA, hmeB and hmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c [H]

COG id: COG5557

COG function: function code C; Polysulphide reductase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 46282; Mature: 46151

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALTREEAALRLADQRPSPGPGRLLRAGWYLLLIALVAAGGVAIAHRTAHGLAATNLTS
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
ITPWGAWIAFYIYFVGLSAGAFLLSSLIYVFGMARFERLGRMALLTALVAMIVALTFVLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGRMERALSALVYFNWLSPLAWEMRFYVIYILLLAAELWFAMRADLVRRAERSRLARWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFGSRSLDTGRDHRMLRILGTIGVPIAIFGVHGGTGTIFAIVKARGMWFSALTPIVFIVS
HHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHH
ALVSGTALLALLYILRQKALKRPVNAGMVADLGKLLGGFLLVDLGLLFYEFLVPLLSMAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HETSVVHLMMEGPYAWTFWILQLGIGMVAPAILLMTRLRESVPLTALACLMVVVGIVGVR
CCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FNIVVPPLIEPVLQGLPAGQYFPNAVEWWTSAGIIAMGLLLFSVAADLLPVDEEVHEIGG
HEEECCHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCC
TAHD
CCCC
>Mature Secondary Structure 
SALTREEAALRLADQRPSPGPGRLLRAGWYLLLIALVAAGGVAIAHRTAHGLAATNLTS
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
ITPWGAWIAFYIYFVGLSAGAFLLSSLIYVFGMARFERLGRMALLTALVAMIVALTFVLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGRMERALSALVYFNWLSPLAWEMRFYVIYILLLAAELWFAMRADLVRRAERSRLARWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFGSRSLDTGRDHRMLRILGTIGVPIAIFGVHGGTGTIFAIVKARGMWFSALTPIVFIVS
HHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHH
ALVSGTALLALLYILRQKALKRPVNAGMVADLGKLLGGFLLVDLGLLFYEFLVPLLSMAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HETSVVHLMMEGPYAWTFWILQLGIGMVAPAILLMTRLRESVPLTALACLMVVVGIVGVR
CCHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FNIVVPPLIEPVLQGLPAGQYFPNAVEWWTSAGIIAMGLLLFSVAADLLPVDEEVHEIGG
HEEECCHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCC
TAHD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475; 11952791 [H]