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The map label for this gene is aroB

Identifier: 51893086

GI number: 51893086

Start: 2089211

End: 2090287

Strand: Reverse

Name: aroB

Synonym: STH1948

Alternate gene names: 51893086

Gene position: 2090287-2089211 (Counterclockwise)

Preceding gene: 51893087

Following gene: 51893085

Centisome position: 58.61

GC content: 71.59

Gene sequence:

>1077_bases
GTGGAACTCGGCGAGGAACGCTACCCGATTTACGTGGGCGCCGGGCTGATGGCGCAGCTGGGCGCGCTGGTGCGGCGGCA
CCTGCCGGAGACCCGGCGGGCCCTGCTGGTGACCGATGCCAACGTCGCGCCCCTCTACGGGGAGGCCGCCCGCGCAGCTC
TGGAGCAGGCCGGGATCACCACCGCCCGGGTGACGGTGCCGGCCGGCGAGGCGTCCAAGTCGCTGTCCCAGGCTTACAGC
CTGTACAGCAGCTGCGTCCGGGCGGAGCTGGACCGCACCAGCGCGGTCGTCGCCCTGGGCGGCGGCGTGGTCGGTGACCT
GGCCGGGTTCGTCGCGGCCACCTACCTGCGGGGGATCCCCCTGGTGCAGGTGCCCACCACCCTGCTCGCACAGGTGGACT
CGTCCATCGGCGGGAAGACCGGCGTCGACCTGCCCCAGGGCAAGAACCTGGTGGGGGCGTTCCACCAGCCCTCTCTGGTG
GTGGCCGACGTGGAGACCCTGAAGAGCCTGCCCCGGCGGGAGCTGTCCGCCGGGATGGCCGAGGTGGTCAAGCACGGGGT
CATCCGGGACGAGGAATTCCTGAAGTACGTGGAGGTCCAGGTGGGCAACGTGCTCGCCGGCGACCCCGCGGTGCTGGAGC
GGGTGGTGGCGGAGAGCTGCCGGATCAAGGCCGAGGTGGTGGCCGCGGACCCCCGCGAGAAGGGGCTGCGGGCGATCCTC
AACTTCGGCCACACCGTGGGCCACGCCCTGGAGGCGGCCATCGGGTTCCGCTGGCTTCACGGCGAGTGCGTCGCGGTCGG
CATGGTTGCGGCGGCGCACATCGCCCGGCACAGCGGCATTGCACAGGAGGGCCGGCTGGAGCTCCGGCTGACGCGTCTGC
TGGAGCGCCTCGACCTGCCCACCACGCTGCCGGAGGGCATGGATCCCAAGGACCTGGAGCCCTTCCTGCGGCGGGACAAG
AAGATCAAGAGCGGAGTGATCCACTGGGTGATGCCCGTGCGGCCCGGCGAGGTGGTCGTCACGCCCGACGTTTCGCCCGA
TGCCATCCGGTGGGGACTGGAAGCGCTGAGGAGGTAA

Upstream 100 bases:

>100_bases
ACGTGCGGATCTGTACGGACCGTCGTTCGCTGCAGGACGTCGTGGCAGAGATCATGGAAAAGCTACAGGAAAGGGGAGAG
CGCGGGTGACAGAGGTCTGG

Downstream 100 bases:

>100_bases
GGATTCAGATGAAGTACCTGTTGTCGTATACGCCGGAGGTTCGGGAGGCCCTGGACCGGAACCGGCCCGTGGTGGCCCTG
GAGTCGACCATCATCAGCCA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MELGEERYPIYVGAGLMAQLGALVRRHLPETRRALLVTDANVAPLYGEAARAALEQAGITTARVTVPAGEASKSLSQAYS
LYSSCVRAELDRTSAVVALGGGVVGDLAGFVAATYLRGIPLVQVPTTLLAQVDSSIGGKTGVDLPQGKNLVGAFHQPSLV
VADVETLKSLPRRELSAGMAEVVKHGVIRDEEFLKYVEVQVGNVLAGDPAVLERVVAESCRIKAEVVAADPREKGLRAIL
NFGHTVGHALEAAIGFRWLHGECVAVGMVAAAHIARHSGIAQEGRLELRLTRLLERLDLPTTLPEGMDPKDLEPFLRRDK
KIKSGVIHWVMPVRPGEVVVTPDVSPDAIRWGLEALRR

Sequences:

>Translated_358_residues
MELGEERYPIYVGAGLMAQLGALVRRHLPETRRALLVTDANVAPLYGEAARAALEQAGITTARVTVPAGEASKSLSQAYS
LYSSCVRAELDRTSAVVALGGGVVGDLAGFVAATYLRGIPLVQVPTTLLAQVDSSIGGKTGVDLPQGKNLVGAFHQPSLV
VADVETLKSLPRRELSAGMAEVVKHGVIRDEEFLKYVEVQVGNVLAGDPAVLERVVAESCRIKAEVVAADPREKGLRAIL
NFGHTVGHALEAAIGFRWLHGECVAVGMVAAAHIARHSGIAQEGRLELRLTRLLERLDLPTTLPEGMDPKDLEPFLRRDK
KIKSGVIHWVMPVRPGEVVVTPDVSPDAIRWGLEALRR
>Mature_358_residues
MELGEERYPIYVGAGLMAQLGALVRRHLPETRRALLVTDANVAPLYGEAARAALEQAGITTARVTVPAGEASKSLSQAYS
LYSSCVRAELDRTSAVVALGGGVVGDLAGFVAATYLRGIPLVQVPTTLLAQVDSSIGGKTGVDLPQGKNLVGAFHQPSLV
VADVETLKSLPRRELSAGMAEVVKHGVIRDEEFLKYVEVQVGNVLAGDPAVLERVVAESCRIKAEVVAADPREKGLRAIL
NFGHTVGHALEAAIGFRWLHGECVAVGMVAAAHIARHSGIAQEGRLELRLTRLLERLDLPTTLPEGMDPKDLEPFLRRDK
KIKSGVIHWVMPVRPGEVVVTPDVSPDAIRWGLEALRR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=348, Percent_Identity=44.2528735632184, Blast_Score=276, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6320332, Length=328, Percent_Identity=38.719512195122, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_SYMTH (Q67N10)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_075777.1
- ProteinModelPortal:   Q67N10
- SMR:   Q67N10
- GeneID:   2980940
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH1948
- NMPDR:   fig|292459.1.peg.1878
- HOGENOM:   HBG632303
- OMA:   GWIDESI
- BioCyc:   STHE292459:STH1948-MONOMER
- BRENDA:   4.2.3.4
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38346; Mature: 38346

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELGEERYPIYVGAGLMAQLGALVRRHLPETRRALLVTDANVAPLYGEAARAALEQAGIT
CCCCCCCCCEEECCHHHHHHHHHHHHHCCHHHCEEEEECCCCCCCCHHHHHHHHHHCCCC
TARVTVPAGEASKSLSQAYSLYSSCVRAELDRTSAVVALGGGVVGDLAGFVAATYLRGIP
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHCCCC
LVQVPTTLLAQVDSSIGGKTGVDLPQGKNLVGAFHQPSLVVADVETLKSLPRRELSAGMA
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEHHHHHHCCHHHHHHHHH
EVVKHGVIRDEEFLKYVEVQVGNVLAGDPAVLERVVAESCRIKAEVVAADPREKGLRAIL
HHHHHCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
NFGHTVGHALEAAIGFRWLHGECVAVGMVAAAHIARHSGIAQEGRLELRLTRLLERLDLP
HHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
TTLPEGMDPKDLEPFLRRDKKIKSGVIHWVMPVRPGEVVVTPDVSPDAIRWGLEALRR
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MELGEERYPIYVGAGLMAQLGALVRRHLPETRRALLVTDANVAPLYGEAARAALEQAGIT
CCCCCCCCCEEECCHHHHHHHHHHHHHCCHHHCEEEEECCCCCCCCHHHHHHHHHHCCCC
TARVTVPAGEASKSLSQAYSLYSSCVRAELDRTSAVVALGGGVVGDLAGFVAATYLRGIP
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHCCCC
LVQVPTTLLAQVDSSIGGKTGVDLPQGKNLVGAFHQPSLVVADVETLKSLPRRELSAGMA
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCEEEEEHHHHHHCCHHHHHHHHH
EVVKHGVIRDEEFLKYVEVQVGNVLAGDPAVLERVVAESCRIKAEVVAADPREKGLRAIL
HHHHHCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHH
NFGHTVGHALEAAIGFRWLHGECVAVGMVAAAHIARHSGIAQEGRLELRLTRLLERLDLP
HHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
TTLPEGMDPKDLEPFLRRDKKIKSGVIHWVMPVRPGEVVVTPDVSPDAIRWGLEALRR
CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA