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The map label for this gene is cobU [H]

Identifier: 51893066

GI number: 51893066

Start: 2071014

End: 2071565

Strand: Reverse

Name: cobU [H]

Synonym: STH1928

Alternate gene names: 51893066

Gene position: 2071565-2071014 (Counterclockwise)

Preceding gene: 51893067

Following gene: 51893065

Centisome position: 58.09

GC content: 73.37

Gene sequence:

>552_bases
ATGGCGGGTGTGATTCTGGTGCTAGGCGGCGCGCGGAGCGGCAAGAGCCGCTGGGCGGAGCATTTGGCTTCGCCGTTCCG
GCGGGTGGTCTATCTGGCCACCGGCCGGGCGGGCGATGCGGAGATGGCCGACCGCATCGCCCGGCACCGGGCGAGCCGTC
CGGCCCACTGGCGCACGGTGGAGGAAGAGCTCAGGCCGGCGGCCGCCCTGGCGCAGGCCCTGCACGAGGCGCCGGCGGAT
GCGGTGCTGCTGGACTGCGTGACCCTGCTCATCTCCAACCACCTGCTGCAGGGGGAGGAGGGGTTCGAAGCCCGGGCCCG
GCAGGAGCTGGCGCAGCTGCTCAGCCTGACCCGTGAGCGCGGCGCGCTGCTCATCGCCGTGTCCAACGAGGTCGGGGCGG
GGCTGGTGCCCGAGCACCGGCTCGGGCGGCTCTTCCGCGACGCCCAGGGGCGGCTGAATCAGTGGCTGGCGCGGGAGGCG
GACCAGGTCTACGCCTGCGTGGCCGGTATCGCCGTCGACCTGAGGCGGATCGGTACGGTGATCCCGGAGTGA

Upstream 100 bases:

>100_bases
TTCAGGGGCTCCAGTGGTTCGCCCGGAATCTCCACCCGGAGCTCTTCGAGCAGTGACCGGGCCGATGGGGCGCTTTCCCG
AAGGGAGCGAGGCGATGCGC

Downstream 100 bases:

>100_bases
GCGTGGCGGAAATGTTTCCCGCGGCGCCCTGGTACCTGCCGCTGGCGGCCCTCGCGGTGGACGCGGCGGTGGGCGATCCC
GCCCGGCTGCCCCATCCGGT

Product: cobinamide kinase and guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MAGVILVLGGARSGKSRWAEHLASPFRRVVYLATGRAGDAEMADRIARHRASRPAHWRTVEEELRPAAALAQALHEAPAD
AVLLDCVTLLISNHLLQGEEGFEARARQELAQLLSLTRERGALLIAVSNEVGAGLVPEHRLGRLFRDAQGRLNQWLAREA
DQVYACVAGIAVDLRRIGTVIPE

Sequences:

>Translated_183_residues
MAGVILVLGGARSGKSRWAEHLASPFRRVVYLATGRAGDAEMADRIARHRASRPAHWRTVEEELRPAAALAQALHEAPAD
AVLLDCVTLLISNHLLQGEEGFEARARQELAQLLSLTRERGALLIAVSNEVGAGLVPEHRLGRLFRDAQGRLNQWLAREA
DQVYACVAGIAVDLRRIGTVIPE
>Mature_182_residues
AGVILVLGGARSGKSRWAEHLASPFRRVVYLATGRAGDAEMADRIARHRASRPAHWRTVEEELRPAAALAQALHEAPADA
VLLDCVTLLISNHLLQGEEGFEARARQELAQLLSLTRERGALLIAVSNEVGAGLVPEHRLGRLFRDAQGRLNQWLAREAD
QVYACVAGIAVDLRRIGTVIPE

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=41.8478260869565, Blast_Score=127, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19948; Mature: 19817

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVILVLGGARSGKSRWAEHLASPFRRVVYLATGRAGDAEMADRIARHRASRPAHWRTV
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
EEELRPAAALAQALHEAPADAVLLDCVTLLISNHLLQGEEGFEARARQELAQLLSLTRER
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
GALLIAVSNEVGAGLVPEHRLGRLFRDAQGRLNQWLAREADQVYACVAGIAVDLRRIGTV
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPE
CCC
>Mature Secondary Structure 
AGVILVLGGARSGKSRWAEHLASPFRRVVYLATGRAGDAEMADRIARHRASRPAHWRTV
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHH
EEELRPAAALAQALHEAPADAVLLDCVTLLISNHLLQGEEGFEARARQELAQLLSLTRER
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
GALLIAVSNEVGAGLVPEHRLGRLFRDAQGRLNQWLAREADQVYACVAGIAVDLRRIGTV
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]