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The map label for this gene is hsdM [C]

Identifier: 51893048

GI number: 51893048

Start: 2051204

End: 2052817

Strand: Reverse

Name: hsdM [C]

Synonym: STH1910

Alternate gene names: 51893048

Gene position: 2052817-2051204 (Counterclockwise)

Preceding gene: 51893049

Following gene: 51893047

Centisome position: 57.56

GC content: 66.11

Gene sequence:

>1614_bases
TTGCCAGCAGGCTGCAATCGGAAGAACTGTGGCGAGAGGGTTGAACGGATGGACAACGAGATGAAGCGCACCCTGTGGGC
CGCGGCGGACAAGCTGCGGTCGTCGATGGACGCAGCCGAGTACAAGCACATCGTGCTGGGCCTGATCTTCCTGAAGTACA
TCTCCGACTCCTTCGTGGCGCAGCGGGAGAGGCTGCGGAAGGTGCTTGCGGACCCCGCGTCCGACCTATATCTGGATGAC
CCGGCCGACCGGGAGGCCGCCCTGGAGGAACGGGAGTACTACACCATGGACAACGTCTTCTGGGTGCCCGACCAGGCGCG
CTGGGAGACCATCCGCGCCCACGCGAAGCAGCCGGACATCGGCGCGCGCATCGACCAGGCCCTGGAGGCCATCGAGGAGG
AGAACCCGCGGCTGAAGGGGCTCCTGGACAAGCGCTACGGCCGGGCCCATCTGGAGCCGGGGCGGCTGGGCGAGCTGGTC
GATCTGATCTCCACCATCGGGTTCGGCGAGGAGCACCGGGCCAGGGACGTGCTCGGCGAGGTGTACGAATACTTCCTGGG
CCAGTTCGCCAGCGCGGAGGGCAAGAAGGGCGGCCAGTTCTACACGCCCGCCTCAGTGGTGAAGCTGCTGGTCGCGATTC
TCGCGCCCTACAAGGGGAAGGTCTACGACCCGTGCTGTGGCTCGGGCGGCATGTTCGTGCAGGCGGAGCGCTTTCTGGAG
AGCAGGGGCGGCCGGTTCGGGGACCTCTCGATCTACGGTCAGGAGGCCAACCCTACCACGTGGCGGCTGGTCGCGATGAA
CCTGACGATCCGGGGGCTCGACTTCAACCTGGGCAAGGAGCCGGCCGACACGTTCCACCGGAACCAGCACCCGGACCTGC
GGGCGGATTACATCCTGGCCAATCCGCCGTTCAACATGTCCGACTGGGGCGGTGAGCGGCTGGTCGATGACCCCCGGTGG
ATCTACGGCACGCCGCCGGCCGGCAACGCCAACTTCGCCTGGCTGCAGCACATCCTCTGGCACCTGGCTCCGGCGGGCCA
GGCGGGCGTGGTGCTCGCCAACGGCTCGATGTCGTCGCAGCAGAACAACGAGGGCGAGATCCGCAAGAACATGGTGGAAG
CCGATGTGGTGGAGGTCATGGTGGCACTGCCGCCGCAGCTTTTCTTCAACACGCAGATCCCGGCCTGCCTCTGGTTCCTG
TGCAAGGACAAGACCAAGAACGGCCGGGATCGCCGGGGCGAGGTGCTCTTCATCGACGCCCGTAAGATGGGGCGGATGGA
GACGCGTGTCAACCGGGTCCTCGACGACGAGGAGATCGCGAAGATCGCCAACACGGTGCACCTCTGGCGGCAGGACCGGG
AGGCGCCGCCCGGACAGGTGTACGAGGACGTGCCGGGCTTCTGTCGCGCGGTCAAGCTGGAGGAGATCGCCGCGAACGGC
TACGTGCTCACCCCTGGGCGGTACGTCGGGGCGGAAGAGGTGGAGGACGACGACGAGACGTTTGCGGAGAAGATGGAGCG
GCTCACGGCGGAGCTGGCCGAGCAGATGAAGAAGGGGGCCGAGCTGGACGAGCAGATTCGACAGATACTGGGGAGGTTAG
GTTATGACCTCTAA

Upstream 100 bases:

>100_bases
CCGTGTACCGAACTGACTATCAATGACTTGGAATTGCAGGCCTGTTCGGTCAGAGTGCCATTGAGCCGGGGATTGCGTAT
CCAGGGTCTGGCCTCACCGG

Downstream 100 bases:

>100_bases
TTGGCGCGAGGCGACCTGGGGTGAGTTGGCTACCCTGGAGTACGGCAAAGCCCTCAGGGATTACAAGACCAGCACCGGTT
CCGTTCCGGTATACGGGACC

Product: type I restriction-modification system DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MPAGCNRKNCGERVERMDNEMKRTLWAAADKLRSSMDAAEYKHIVLGLIFLKYISDSFVAQRERLRKVLADPASDLYLDD
PADREAALEEREYYTMDNVFWVPDQARWETIRAHAKQPDIGARIDQALEAIEEENPRLKGLLDKRYGRAHLEPGRLGELV
DLISTIGFGEEHRARDVLGEVYEYFLGQFASAEGKKGGQFYTPASVVKLLVAILAPYKGKVYDPCCGSGGMFVQAERFLE
SRGGRFGDLSIYGQEANPTTWRLVAMNLTIRGLDFNLGKEPADTFHRNQHPDLRADYILANPPFNMSDWGGERLVDDPRW
IYGTPPAGNANFAWLQHILWHLAPAGQAGVVLANGSMSSQQNNEGEIRKNMVEADVVEVMVALPPQLFFNTQIPACLWFL
CKDKTKNGRDRRGEVLFIDARKMGRMETRVNRVLDDEEIAKIANTVHLWRQDREAPPGQVYEDVPGFCRAVKLEEIAANG
YVLTPGRYVGAEEVEDDDETFAEKMERLTAELAEQMKKGAELDEQIRQILGRLGYDL

Sequences:

>Translated_537_residues
MPAGCNRKNCGERVERMDNEMKRTLWAAADKLRSSMDAAEYKHIVLGLIFLKYISDSFVAQRERLRKVLADPASDLYLDD
PADREAALEEREYYTMDNVFWVPDQARWETIRAHAKQPDIGARIDQALEAIEEENPRLKGLLDKRYGRAHLEPGRLGELV
DLISTIGFGEEHRARDVLGEVYEYFLGQFASAEGKKGGQFYTPASVVKLLVAILAPYKGKVYDPCCGSGGMFVQAERFLE
SRGGRFGDLSIYGQEANPTTWRLVAMNLTIRGLDFNLGKEPADTFHRNQHPDLRADYILANPPFNMSDWGGERLVDDPRW
IYGTPPAGNANFAWLQHILWHLAPAGQAGVVLANGSMSSQQNNEGEIRKNMVEADVVEVMVALPPQLFFNTQIPACLWFL
CKDKTKNGRDRRGEVLFIDARKMGRMETRVNRVLDDEEIAKIANTVHLWRQDREAPPGQVYEDVPGFCRAVKLEEIAANG
YVLTPGRYVGAEEVEDDDETFAEKMERLTAELAEQMKKGAELDEQIRQILGRLGYDL
>Mature_536_residues
PAGCNRKNCGERVERMDNEMKRTLWAAADKLRSSMDAAEYKHIVLGLIFLKYISDSFVAQRERLRKVLADPASDLYLDDP
ADREAALEEREYYTMDNVFWVPDQARWETIRAHAKQPDIGARIDQALEAIEEENPRLKGLLDKRYGRAHLEPGRLGELVD
LISTIGFGEEHRARDVLGEVYEYFLGQFASAEGKKGGQFYTPASVVKLLVAILAPYKGKVYDPCCGSGGMFVQAERFLES
RGGRFGDLSIYGQEANPTTWRLVAMNLTIRGLDFNLGKEPADTFHRNQHPDLRADYILANPPFNMSDWGGERLVDDPRWI
YGTPPAGNANFAWLQHILWHLAPAGQAGVVLANGSMSSQQNNEGEIRKNMVEADVVEVMVALPPQLFFNTQIPACLWFLC
KDKTKNGRDRRGEVLFIDARKMGRMETRVNRVLDDEEIAKIANTVHLWRQDREAPPGQVYEDVPGFCRAVKLEEIAANGY
VLTPGRYVGAEEVEDDDETFAEKMERLTAELAEQMKKGAELDEQIRQILGRLGYDL

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=325, Percent_Identity=22.4615384615385, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 60723; Mature: 60591

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAGCNRKNCGERVERMDNEMKRTLWAAADKLRSSMDAAEYKHIVLGLIFLKYISDSFVA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRERLRKVLADPASDLYLDDPADREAALEEREYYTMDNVFWVPDQARWETIRAHAKQPDI
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHEEEECCEEECCCHHHHHHHHHHCCCCCC
GARIDQALEAIEEENPRLKGLLDKRYGRAHLEPGRLGELVDLISTIGFGEEHRARDVLGE
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VYEYFLGQFASAEGKKGGQFYTPASVVKLLVAILAPYKGKVYDPCCGSGGMFVQAERFLE
HHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
SRGGRFGDLSIYGQEANPTTWRLVAMNLTIRGLDFNLGKEPADTFHRNQHPDLRADYILA
HCCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCEEEE
NPPFNMSDWGGERLVDDPRWIYGTPPAGNANFAWLQHILWHLAPAGQAGVVLANGSMSSQ
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCC
QNNEGEIRKNMVEADVVEVMVALPPQLFFNTQIPACLWFLCKDKTKNGRDRRGEVLFIDA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEH
RKMGRMETRVNRVLDDEEIAKIANTVHLWRQDREAPPGQVYEDVPGFCRAVKLEEIAANG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHCCC
YVLTPGRYVGAEEVEDDDETFAEKMERLTAELAEQMKKGAELDEQIRQILGRLGYDL
EEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PAGCNRKNCGERVERMDNEMKRTLWAAADKLRSSMDAAEYKHIVLGLIFLKYISDSFVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRERLRKVLADPASDLYLDDPADREAALEEREYYTMDNVFWVPDQARWETIRAHAKQPDI
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHEEEECCEEECCCHHHHHHHHHHCCCCCC
GARIDQALEAIEEENPRLKGLLDKRYGRAHLEPGRLGELVDLISTIGFGEEHRARDVLGE
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
VYEYFLGQFASAEGKKGGQFYTPASVVKLLVAILAPYKGKVYDPCCGSGGMFVQAERFLE
HHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
SRGGRFGDLSIYGQEANPTTWRLVAMNLTIRGLDFNLGKEPADTFHRNQHPDLRADYILA
HCCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCEEEE
NPPFNMSDWGGERLVDDPRWIYGTPPAGNANFAWLQHILWHLAPAGQAGVVLANGSMSSQ
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCC
QNNEGEIRKNMVEADVVEVMVALPPQLFFNTQIPACLWFLCKDKTKNGRDRRGEVLFIDA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEH
RKMGRMETRVNRVLDDEEIAKIANTVHLWRQDREAPPGQVYEDVPGFCRAVKLEEIAANG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHCCC
YVLTPGRYVGAEEVEDDDETFAEKMERLTAELAEQMKKGAELDEQIRQILGRLGYDL
EEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]