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The map label for this gene is 51893047

Identifier: 51893047

GI number: 51893047

Start: 2049976

End: 2051178

Strand: Reverse

Name: 51893047

Synonym: STH1909

Alternate gene names: NA

Gene position: 2051178-2049976 (Counterclockwise)

Preceding gene: 51893048

Following gene: 51893046

Centisome position: 57.52

GC content: 57.27

Gene sequence:

>1203_bases
TTGGCTACCCTGGAGTACGGCAAAGCCCTCAGGGATTACAAGACCAGCACCGGTTCCGTTCCGGTATACGGGACCAACGG
GCCGATTGGCTGGACAAACAAGCCCCTCTGCCCCTTTCCGACCGTCATCATCGGGCGTAAGGGCGCCTACCGTGGAGTTC
ATCTATCGCCCTCTCCCTGTTGGGTCATAGACACCGCGTTCTACATCAGTCCGAAGCAACCTCTGGACATTCGCTGGGCT
TATTACCAGTTGCTTACACAAGACATCAACGGGATGGACAGCGGGTCGGCGATTCCTTCGACCAGCAGGGAGGAGTTCTA
CCGACTTCCCGTCAAAGTCCCGCCGCTCGCGGTTCAAAAGCAGATTGCCGATGTTCTTGGAACGCTAGATTCCAGAATCG
CGAACGTGCAAAGCACGAACATTTGCCTCGAGTCAATAGGCCAGGCAATCTTTAAGTCATGGTTTGTTGATTTTGACCCC
GTCCGCGCCAAGGCCGAAGGCCGGGATCCGGAAGGCGTGGACGAGGATACGGCAGCGTGGTTTCCGGAGGAGTTTCAGGA
TTCGGAACTAGGCCCAATTCCCAAAGGATGGCGTGTCGACACCATTGACAGCGTTATCTCGTGTGTGGGGGGCTCGACAC
CCAGCACCAAGGAGCCTGCCTACTGGAACCCACCGGAATACCACTGGGTAACGCCCAAGGACCTTTCAGGCCAGTCCACG
CCCGTACTGCTGACAACTGAGCGGATGATCTCCGAGGCTGGCCTGAAAAAGATCAGCAGCGGACTCCTGCCAGAAGGCAC
ACTCCTCTTGTCGTCCCGTGCGCCGATCGGTTACCTCGCCATTACGAAGATCCCCACAGCGATCAACCAGGGGTTCATTG
CCATGCCGCCCGCTGGGCAGCTATCTCCGGAGTACATGCTGTTCTGGAGTCATTACAACCTCGATACGATCAAACAGCAC
GCAAACGGCTCTACATTCATGGAAATTAGCAAGGCTGCGTTCCGCAAGATCAAGCTCGTTGTGCCTCCGGCGCAGTTGGT
CAACCGCTTTACCCAGATTGCCCAGACAGTACTAGAAAGGATAGCGGCCAATGAACGATACCGAATGCAACTAGTCAACC
TCCGCGACACCCTGCTCCCCCGCCTCATCGCCGGCAAGCTTCGCGTGCCCGAGGCCGAGGAGGCCCTGAAGGAGGTGCTG
TGA

Upstream 100 bases:

>100_bases
GAGCAGATGAAGAAGGGGGCCGAGCTGGACGAGCAGATTCGACAGATACTGGGGAGGTTAGGTTATGACCTCTAATTGGC
GCGAGGCGACCTGGGGTGAG

Downstream 100 bases:

>100_bases
TGCCCGTCCTGAGCGAAGAGACCCTGGAACAGGCCGCACTCGAATGGCTCCGCGAGCTCGGCTGGGCGGTCGCACATGGG
CCCGACATCTCCCCCGTGGA

Product: type I restriction-modification system specificity determinant protein

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MATLEYGKALRDYKTSTGSVPVYGTNGPIGWTNKPLCPFPTVIIGRKGAYRGVHLSPSPCWVIDTAFYISPKQPLDIRWA
YYQLLTQDINGMDSGSAIPSTSREEFYRLPVKVPPLAVQKQIADVLGTLDSRIANVQSTNICLESIGQAIFKSWFVDFDP
VRAKAEGRDPEGVDEDTAAWFPEEFQDSELGPIPKGWRVDTIDSVISCVGGSTPSTKEPAYWNPPEYHWVTPKDLSGQST
PVLLTTERMISEAGLKKISSGLLPEGTLLLSSRAPIGYLAITKIPTAINQGFIAMPPAGQLSPEYMLFWSHYNLDTIKQH
ANGSTFMEISKAAFRKIKLVVPPAQLVNRFTQIAQTVLERIAANERYRMQLVNLRDTLLPRLIAGKLRVPEAEEALKEVL

Sequences:

>Translated_400_residues
MATLEYGKALRDYKTSTGSVPVYGTNGPIGWTNKPLCPFPTVIIGRKGAYRGVHLSPSPCWVIDTAFYISPKQPLDIRWA
YYQLLTQDINGMDSGSAIPSTSREEFYRLPVKVPPLAVQKQIADVLGTLDSRIANVQSTNICLESIGQAIFKSWFVDFDP
VRAKAEGRDPEGVDEDTAAWFPEEFQDSELGPIPKGWRVDTIDSVISCVGGSTPSTKEPAYWNPPEYHWVTPKDLSGQST
PVLLTTERMISEAGLKKISSGLLPEGTLLLSSRAPIGYLAITKIPTAINQGFIAMPPAGQLSPEYMLFWSHYNLDTIKQH
ANGSTFMEISKAAFRKIKLVVPPAQLVNRFTQIAQTVLERIAANERYRMQLVNLRDTLLPRLIAGKLRVPEAEEALKEVL
>Mature_399_residues
ATLEYGKALRDYKTSTGSVPVYGTNGPIGWTNKPLCPFPTVIIGRKGAYRGVHLSPSPCWVIDTAFYISPKQPLDIRWAY
YQLLTQDINGMDSGSAIPSTSREEFYRLPVKVPPLAVQKQIADVLGTLDSRIANVQSTNICLESIGQAIFKSWFVDFDPV
RAKAEGRDPEGVDEDTAAWFPEEFQDSELGPIPKGWRVDTIDSVISCVGGSTPSTKEPAYWNPPEYHWVTPKDLSGQSTP
VLLTTERMISEAGLKKISSGLLPEGTLLLSSRAPIGYLAITKIPTAINQGFIAMPPAGQLSPEYMLFWSHYNLDTIKQHA
NGSTFMEISKAAFRKIKLVVPPAQLVNRFTQIAQTVLERIAANERYRMQLVNLRDTLLPRLIAGKLRVPEAEEALKEVL

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 44295; Mature: 44164

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLEYGKALRDYKTSTGSVPVYGTNGPIGWTNKPLCPFPTVIIGRKGAYRGVHLSPSPC
CCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCC
WVIDTAFYISPKQPLDIRWAYYQLLTQDINGMDSGSAIPSTSREEFYRLPVKVPPLAVQK
EEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEECCCCCCCHHHHH
QIADVLGTLDSRIANVQSTNICLESIGQAIFKSWFVDFDPVRAKAEGRDPEGVDEDTAAW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHC
FPEEFQDSELGPIPKGWRVDTIDSVISCVGGSTPSTKEPAYWNPPEYHWVTPKDLSGQST
CCHHHCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
PVLLTTERMISEAGLKKISSGLLPEGTLLLSSRAPIGYLAITKIPTAINQGFIAMPPAGQ
CEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCHHHCCCEEECCCCCC
LSPEYMLFWSHYNLDTIKQHANGSTFMEISKAAFRKIKLVVPPAQLVNRFTQIAQTVLER
CCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHH
IAANERYRMQLVNLRDTLLPRLIAGKLRVPEAEEALKEVL
HHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
>Mature Secondary Structure 
ATLEYGKALRDYKTSTGSVPVYGTNGPIGWTNKPLCPFPTVIIGRKGAYRGVHLSPSPC
CCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCCC
WVIDTAFYISPKQPLDIRWAYYQLLTQDINGMDSGSAIPSTSREEFYRLPVKVPPLAVQK
EEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEECCCCCCCHHHHH
QIADVLGTLDSRIANVQSTNICLESIGQAIFKSWFVDFDPVRAKAEGRDPEGVDEDTAAW
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHC
FPEEFQDSELGPIPKGWRVDTIDSVISCVGGSTPSTKEPAYWNPPEYHWVTPKDLSGQST
CCHHHCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
PVLLTTERMISEAGLKKISSGLLPEGTLLLSSRAPIGYLAITKIPTAINQGFIAMPPAGQ
CEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCHHHCCCEEECCCCCC
LSPEYMLFWSHYNLDTIKQHANGSTFMEISKAAFRKIKLVVPPAQLVNRFTQIAQTVLER
CCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHH
IAANERYRMQLVNLRDTLLPRLIAGKLRVPEAEEALKEVL
HHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]