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The map label for this gene is 51892917

Identifier: 51892917

GI number: 51892917

Start: 1923022

End: 1924575

Strand: Reverse

Name: 51892917

Synonym: STH1779

Alternate gene names: NA

Gene position: 1924575-1923022 (Counterclockwise)

Preceding gene: 51892918

Following gene: 51892916

Centisome position: 53.97

GC content: 67.12

Gene sequence:

>1554_bases
GTGAAGGCAATTCTCTATGTGATCGTTGCCGTCATCGCGCTGATCCTCGGTGGTGCGGCCGGTGTGGCCGGCGGGTACTA
CTGGTTCGAGCGCGAGTCCCGGAAGAAGCTGAACTCCGCCGAGGCGCGGGCACGCCACATCGTCGACGAGGCCCTGCGGG
AGGCGGAGGCTAAGAAGAAGGAAGCGATCCTCGAGGCCAAGGAAGAGGTGCACCGGCTGCGCACCGAGGCCGAGCGGGAG
CTGAAGGAGCGGCGCGCGGAGCTCCAGCGGCTGGAGCGCCGGGTGCTGCAGAAGGAAGAGCAGCTCGACCGCAAGGTGGA
GCAGCTGGAGCGGAAGGAAGAGACCCTCAGCCGGAAGGAGCGGGAGCTCGACCGCAAGAACCAGCAGGCACAGGAGCTGG
TCAACAAGCAGATGGCCGAGCTCGAGCGCATCTCCCAGCTCACGATGGAGGAGGCGCGGGAGCTGTTCCTGAAGCAGGTG
GAGCAGGAGGCCCGCGCGGATGCCGCCAAGCTGATCCGGGAGATCGACGCCGAGGCCCGGGAGAATGCCGAGAAGCGCGC
CCGGGAACTGGTGGGTCTGGCCGTGCAGCGGGTGGCCGCGGATCACTCCTCGGAGCTGACCGTCACGGTGGTTTCCCTGC
CCAACGACGAGATGAAGGGCAGGATCATCGGCCGGGAAGGGCGGAACATCCGTACACTGGAGACGCTCACCGGCGTGGAT
CTCATCATCGACGATACTCCCGAAGCGGTGGTGCTTTCGGCGTTCGATCCGGTGCGGCGTGAGGTCGCCAAGATCGCGCT
GCAGAAGCTGATCCAGGACGGCCGCATCCACCCGGCCCGGATCGAGGAGATGGTGGAGAAGGCGCAGAAGGAGGTGGAGG
CCCGGATCCGCGAGGAGGGTGACGCCGCCTGCTTCGAGCTGGGCATCCACAACCTGCACCCGGAGCTGGTGAAGCTGCTG
GGGCGCCTGAAGTTCCGCACGTCGTACGGACAGAACGTGCTGAAGCACTCCATCGAGGTCGCGCATCTCGCCGGCATCAT
GGCCGCCGAGCTGGGTGTCAACGTGGAGGTGGCCAAGCGGGCCGGGTTGCTGCATGACATCGGCAAGGCGGTGGACCACG
AGATCGAGGGCTCCCACGTGGCCATCGGCGTGAGCCTGCTGCGGCGGTACAAGGAGCATCCCGACGTGATCCACGCCATG
GAGTGCCACCACGGCGACGTCGAGCCCCGCTCGGTGGAGGCGCATCTGGTGGCCGCGGCGGACGCCATCTCGGCCGCACG
GCCCGGAGCACGGCGGGAGACCCTGGAGACGTACATCAAGCGGCTGGAGAAGCTGGAGGCCCTGGCGGACAGCTTCGACG
GCGTCGACAAGTCCTACGCGATCCAGGCCGGGCGCGAGATCCGGGTCATGGTGAAGCCGGAGAAGATCGACGACTACGCC
GCGCTGAAGCTGACCAAGGAGATCGCGCGCAAGATCGAGGAAGAGCTGGAGTACCCGGGACAGATCCGGGTGGTCGTCGT
GCGGGAGACGCGCGCGGTGGAGTACGCCCGCTGA

Upstream 100 bases:

>100_bases
CGTGTGTACCCATATGGCGAGCACGGAGTACGGACCGGCTTGTGGTCCGTTTTTCTTTTCCCTCGATTGTGCGACTTGAT
CACTTTCATGCGGACAGGAG

Downstream 100 bases:

>100_bases
CGCAGGCGAACTTTTCTCCCGGCGCAGACGTCATAAGAACAGAGCGCACACTGCGCCGACACTCGTCCTGAGCTGTCGGC
GCAGCGTCGCTCGGGCGGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKAILYVIVAVIALILGGAAGVAGGYYWFERESRKKLNSAEARARHIVDEALREAEAKKKEAILEAKEEVHRLRTEAERE
LKERRAELQRLERRVLQKEEQLDRKVEQLERKEETLSRKERELDRKNQQAQELVNKQMAELERISQLTMEEARELFLKQV
EQEARADAAKLIREIDAEARENAEKRARELVGLAVQRVAADHSSELTVTVVSLPNDEMKGRIIGREGRNIRTLETLTGVD
LIIDDTPEAVVLSAFDPVRREVAKIALQKLIQDGRIHPARIEEMVEKAQKEVEARIREEGDAACFELGIHNLHPELVKLL
GRLKFRTSYGQNVLKHSIEVAHLAGIMAAELGVNVEVAKRAGLLHDIGKAVDHEIEGSHVAIGVSLLRRYKEHPDVIHAM
ECHHGDVEPRSVEAHLVAAADAISAARPGARRETLETYIKRLEKLEALADSFDGVDKSYAIQAGREIRVMVKPEKIDDYA
ALKLTKEIARKIEEELEYPGQIRVVVVRETRAVEYAR

Sequences:

>Translated_517_residues
MKAILYVIVAVIALILGGAAGVAGGYYWFERESRKKLNSAEARARHIVDEALREAEAKKKEAILEAKEEVHRLRTEAERE
LKERRAELQRLERRVLQKEEQLDRKVEQLERKEETLSRKERELDRKNQQAQELVNKQMAELERISQLTMEEARELFLKQV
EQEARADAAKLIREIDAEARENAEKRARELVGLAVQRVAADHSSELTVTVVSLPNDEMKGRIIGREGRNIRTLETLTGVD
LIIDDTPEAVVLSAFDPVRREVAKIALQKLIQDGRIHPARIEEMVEKAQKEVEARIREEGDAACFELGIHNLHPELVKLL
GRLKFRTSYGQNVLKHSIEVAHLAGIMAAELGVNVEVAKRAGLLHDIGKAVDHEIEGSHVAIGVSLLRRYKEHPDVIHAM
ECHHGDVEPRSVEAHLVAAADAISAARPGARRETLETYIKRLEKLEALADSFDGVDKSYAIQAGREIRVMVKPEKIDDYA
ALKLTKEIARKIEEELEYPGQIRVVVVRETRAVEYAR
>Mature_517_residues
MKAILYVIVAVIALILGGAAGVAGGYYWFERESRKKLNSAEARARHIVDEALREAEAKKKEAILEAKEEVHRLRTEAERE
LKERRAELQRLERRVLQKEEQLDRKVEQLERKEETLSRKERELDRKNQQAQELVNKQMAELERISQLTMEEARELFLKQV
EQEARADAAKLIREIDAEARENAEKRARELVGLAVQRVAADHSSELTVTVVSLPNDEMKGRIIGREGRNIRTLETLTGVD
LIIDDTPEAVVLSAFDPVRREVAKIALQKLIQDGRIHPARIEEMVEKAQKEVEARIREEGDAACFELGIHNLHPELVKLL
GRLKFRTSYGQNVLKHSIEVAHLAGIMAAELGVNVEVAKRAGLLHDIGKAVDHEIEGSHVAIGVSLLRRYKEHPDVIHAM
ECHHGDVEPRSVEAHLVAAADAISAARPGARRETLETYIKRLEKLEALADSFDGVDKSYAIQAGREIRVMVKPEKIDDYA
ALKLTKEIARKIEEELEYPGQIRVVVVRETRAVEYAR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_SYMTH (Q67NH9)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_075608.1
- ProteinModelPortal:   Q67NH9
- GeneID:   2982183
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH1779
- NMPDR:   fig|292459.1.peg.1716
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- BioCyc:   STHE292459:STH1779-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58574; Mature: 58574

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x131b7a90)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAILYVIVAVIALILGGAAGVAGGYYWFERESRKKLNSAEARARHIVDEALREAEAKKK
CHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAILEAKEEVHRLRTEAERELKERRAELQRLERRVLQKEEQLDRKVEQLERKEETLSRKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELDRKNQQAQELVNKQMAELERISQLTMEEARELFLKQVEQEARADAAKLIREIDAEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAEKRARELVGLAVQRVAADHSSELTVTVVSLPNDEMKGRIIGREGRNIRTLETLTGVD
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCCCCCCCHHHHHCCCE
LIIDDTPEAVVLSAFDPVRREVAKIALQKLIQDGRIHPARIEEMVEKAQKEVEARIREEG
EEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DAACFELGIHNLHPELVKLLGRLKFRTSYGQNVLKHSIEVAHLAGIMAAELGVNVEVAKR
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AGLLHDIGKAVDHEIEGSHVAIGVSLLRRYKEHPDVIHAMECHHGDVEPRSVEAHLVAAA
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHH
DAISAARPGARRETLETYIKRLEKLEALADSFDGVDKSYAIQAGREIRVMVKPEKIDDYA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEEECCCCCCHHH
ALKLTKEIARKIEEELEYPGQIRVVVVRETRAVEYAR
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHCCCH
>Mature Secondary Structure
MKAILYVIVAVIALILGGAAGVAGGYYWFERESRKKLNSAEARARHIVDEALREAEAKKK
CHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAILEAKEEVHRLRTEAERELKERRAELQRLERRVLQKEEQLDRKVEQLERKEETLSRKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RELDRKNQQAQELVNKQMAELERISQLTMEEARELFLKQVEQEARADAAKLIREIDAEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENAEKRARELVGLAVQRVAADHSSELTVTVVSLPNDEMKGRIIGREGRNIRTLETLTGVD
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEECCCCCCCCHHHHHCCCE
LIIDDTPEAVVLSAFDPVRREVAKIALQKLIQDGRIHPARIEEMVEKAQKEVEARIREEG
EEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DAACFELGIHNLHPELVKLLGRLKFRTSYGQNVLKHSIEVAHLAGIMAAELGVNVEVAKR
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AGLLHDIGKAVDHEIEGSHVAIGVSLLRRYKEHPDVIHAMECHHGDVEPRSVEAHLVAAA
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHH
DAISAARPGARRETLETYIKRLEKLEALADSFDGVDKSYAIQAGREIRVMVKPEKIDDYA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEEECCCCCCHHH
ALKLTKEIARKIEEELEYPGQIRVVVVRETRAVEYAR
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA