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The map label for this gene is ccdA [H]

Identifier: 51892870

GI number: 51892870

Start: 1882398

End: 1883102

Strand: Reverse

Name: ccdA [H]

Synonym: STH1732

Alternate gene names: 51892870

Gene position: 1883102-1882398 (Counterclockwise)

Preceding gene: 51892871

Following gene: 51892869

Centisome position: 52.81

GC content: 67.23

Gene sequence:

>705_bases
ATGGCTTCGCCGAACCTGTTCCTCGCTTTCGGCGCAGGGGTGCTCTCGTTCGTGTCGCCCTGCGTGCTGCCGATCTACCC
GTCTTTCCTCAGCTACCTGACCGGCGTTTCGGTGGACCAGCTCTCCGAGGGCAGCCGGGCTGTGCGCGCCCATGTGCTGA
AGCACAGCCTGGCCTTCTTCGCGGGATTCTCGGTGATCTACGTCGCACTGGGCCTCACCGCCAGCGCACTGGGTTCCTTT
TTCTACAGCAGCCGCTCCTGGCTCCCGGTGGTGGGCGGAATCTTCATCGCGCTGATGGGGTTGTCGATGATGGGGATTCT
GCGCGTGCCTTTCCTGATGCGGGACACCCGGCGGCAGCTGGCCAGCCGTCCGGAAGGGTACCTCGGCTCGGCGCTGATCG
GCCTCACCTTCGCCGCGGGCTGGACGCCCTGCATCGGACCGATCCTGGGCGCCGTGCTCGCCCTGGCGGCCACCAGCCCG
GGGTACGGGGGACTGTTGCTGCTGGCGTATTCGGTGGGCTTTGCCCTGCCCTTCATCGGTATGGCGTACGCCCTGGGCTC
GGTCCGAAGCCTCGCCCGGCACTCGGTGGCGATTCAGCGGGTGGGCGGCGCCGTGATGGTGTTCATGGGCATCCTGCTCG
CGACCGGCGGGCTGGAGCGCATTTCGGCCTGGCTCCTGGAGATCACGGGGTTTACGGGGTTCTGA

Upstream 100 bases:

>100_bases
GAGGGCATCGTGCGTGCGGTGTACCAATACCAGATGTCGCGGGCGCAGATTGAGTTTGAAGTGCAGCGCCTGATGGCCCG
CTGACGGGGAGTCGATGCCC

Downstream 100 bases:

>100_bases
CGGCAACCCTGTCTCGTGTGGCTTGACTGGCAAGGGGGGAGTTTCGCACTGGCCGCAGTACACGCAGCCAACTGTCCGGA
CTGTCAGCGGCCGCTGCCGG

Product: cytochrome C biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MASPNLFLAFGAGVLSFVSPCVLPIYPSFLSYLTGVSVDQLSEGSRAVRAHVLKHSLAFFAGFSVIYVALGLTASALGSF
FYSSRSWLPVVGGIFIALMGLSMMGILRVPFLMRDTRRQLASRPEGYLGSALIGLTFAAGWTPCIGPILGAVLALAATSP
GYGGLLLLAYSVGFALPFIGMAYALGSVRSLARHSVAIQRVGGAVMVFMGILLATGGLERISAWLLEITGFTGF

Sequences:

>Translated_234_residues
MASPNLFLAFGAGVLSFVSPCVLPIYPSFLSYLTGVSVDQLSEGSRAVRAHVLKHSLAFFAGFSVIYVALGLTASALGSF
FYSSRSWLPVVGGIFIALMGLSMMGILRVPFLMRDTRRQLASRPEGYLGSALIGLTFAAGWTPCIGPILGAVLALAATSP
GYGGLLLLAYSVGFALPFIGMAYALGSVRSLARHSVAIQRVGGAVMVFMGILLATGGLERISAWLLEITGFTGF
>Mature_233_residues
ASPNLFLAFGAGVLSFVSPCVLPIYPSFLSYLTGVSVDQLSEGSRAVRAHVLKHSLAFFAGFSVIYVALGLTASALGSFF
YSSRSWLPVVGGIFIALMGLSMMGILRVPFLMRDTRRQLASRPEGYLGSALIGLTFAAGWTPCIGPILGAVLALAATSPG
YGGLLLLAYSVGFALPFIGMAYALGSVRSLARHSVAIQRVGGAVMVFMGILLATGGLERISAWLLEITGFTGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 24497; Mature: 24366

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPNLFLAFGAGVLSFVSPCVLPIYPSFLSYLTGVSVDQLSEGSRAVRAHVLKHSLAFF
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
AGFSVIYVALGLTASALGSFFYSSRSWLPVVGGIFIALMGLSMMGILRVPFLMRDTRRQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRPEGYLGSALIGLTFAAGWTPCIGPILGAVLALAATSPGYGGLLLLAYSVGFALPFIG
HCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
MAYALGSVRSLARHSVAIQRVGGAVMVFMGILLATGGLERISAWLLEITGFTGF
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASPNLFLAFGAGVLSFVSPCVLPIYPSFLSYLTGVSVDQLSEGSRAVRAHVLKHSLAFF
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
AGFSVIYVALGLTASALGSFFYSSRSWLPVVGGIFIALMGLSMMGILRVPFLMRDTRRQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASRPEGYLGSALIGLTFAAGWTPCIGPILGAVLALAATSPGYGGLLLLAYSVGFALPFIG
HCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
MAYALGSVRSLARHSVAIQRVGGAVMVFMGILLATGGLERISAWLLEITGFTGF
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]