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The map label for this gene is mta [H]

Identifier: 51892596

GI number: 51892596

Start: 1601178

End: 1601942

Strand: Reverse

Name: mta [H]

Synonym: STH1458

Alternate gene names: 51892596

Gene position: 1601942-1601178 (Counterclockwise)

Preceding gene: 51892598

Following gene: 51892582

Centisome position: 44.92

GC content: 66.93

Gene sequence:

>765_bases
ATGGCCCTGACGGTGAAGGCAGTGGCCGAACTGGCCGGCATCAGCGTCCGGACCCTGCACCACTACGACGAGATCGGGCT
TCTGAAGCCGGCCGGGCAGTCGGCCGCAGGGTATCGGCTCTACTCCAGGGAGGATCTGGAACGGCTGCAGCAGATCCTGT
TGTTCCGGGAACTGGGGTTCAGCCTGAGGGAGATCGCGGCCATCCTGGAAAGCCCCGGCTTCGACCGGCGGCAGGCCCTG
CTGGCCCACCGGGAGGCGCTGCTGCAGCGGAAAGCCCGCATCGAGCGGTTGATCGCCACGGTCGACCGCACGCTGGCGGC
AATGGAAAGGGAGGATGCCCCCATGGACACCAGGGAAGAGATGAAGGAACTGTTCGACGGGTTCGATCCGGGCGAGTACG
AGGAGGAGGCCAGGCAGCGCTGGGGCGGATCCCGGGAGTTCCGGGAGTCGGCGGAGCGGACCCGGAAGTACACCCGGCAG
GACTGGCAGAGAATCGCGGCGGAGGACGGCGAGATCTACGGCAACATCGCCCGCCTGATGGACCGGGATCCCGCCGACCC
TGCCGTGCAGGAGTGGGTCGGCCGCTGGCACGAGCACATCAGCAAGTGGTACTACGACTGCTCGCTGGAGGTCTTCCGCG
GGCTGGGCGAGATGTACGTGCAGGACGAGCGGTTCACCCGGAACATCGACATGACGAAGCCCGGCCTCGCCCGGTTCCTG
CGGGACGCGATGCAGATCTACTGCGACCGGCGGGAAGGGAAGTAA

Upstream 100 bases:

>100_bases
AACACACGTGCCGTTTCATCCTCGTCGCCGCGACTCGCCAAACTGGCTGTTGACCCTCACGCAACGTGAGGGTTTATGCT
CGGAGACAGGAGGTGAGCAG

Downstream 100 bases:

>100_bases
GGCGCAGAACGCCCGGGACGTACGGACCCATCGGCCCCCCTCCCTCCACATGCTCTCCCGGCGGCCAACGGACCGCCTGA
ACACTGTGTACGGACGCGCA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MALTVKAVAELAGISVRTLHHYDEIGLLKPAGQSAAGYRLYSREDLERLQQILLFRELGFSLREIAAILESPGFDRRQAL
LAHREALLQRKARIERLIATVDRTLAAMEREDAPMDTREEMKELFDGFDPGEYEEEARQRWGGSREFRESAERTRKYTRQ
DWQRIAAEDGEIYGNIARLMDRDPADPAVQEWVGRWHEHISKWYYDCSLEVFRGLGEMYVQDERFTRNIDMTKPGLARFL
RDAMQIYCDRREGK

Sequences:

>Translated_254_residues
MALTVKAVAELAGISVRTLHHYDEIGLLKPAGQSAAGYRLYSREDLERLQQILLFRELGFSLREIAAILESPGFDRRQAL
LAHREALLQRKARIERLIATVDRTLAAMEREDAPMDTREEMKELFDGFDPGEYEEEARQRWGGSREFRESAERTRKYTRQ
DWQRIAAEDGEIYGNIARLMDRDPADPAVQEWVGRWHEHISKWYYDCSLEVFRGLGEMYVQDERFTRNIDMTKPGLARFL
RDAMQIYCDRREGK
>Mature_253_residues
ALTVKAVAELAGISVRTLHHYDEIGLLKPAGQSAAGYRLYSREDLERLQQILLFRELGFSLREIAAILESPGFDRRQALL
AHREALLQRKARIERLIATVDRTLAAMEREDAPMDTREEMKELFDGFDPGEYEEEARQRWGGSREFRESAERTRKYTRQD
WQRIAAEDGEIYGNIARLMDRDPADPAVQEWVGRWHEHISKWYYDCSLEVFRGLGEMYVQDERFTRNIDMTKPGLARFLR
DAMQIYCDRREGK

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 29765; Mature: 29634

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTVKAVAELAGISVRTLHHYDEIGLLKPAGQSAAGYRLYSREDLERLQQILLFRELGF
CCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
SLREIAAILESPGFDRRQALLAHREALLQRKARIERLIATVDRTLAAMEREDAPMDTREE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
MKELFDGFDPGEYEEEARQRWGGSREFRESAERTRKYTRQDWQRIAAEDGEIYGNIARLM
HHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DRDPADPAVQEWVGRWHEHISKWYYDCSLEVFRGLGEMYVQDERFTRNIDMTKPGLARFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RDAMQIYCDRREGK
HHHHHHHHHHCCCC
>Mature Secondary Structure 
ALTVKAVAELAGISVRTLHHYDEIGLLKPAGQSAAGYRLYSREDLERLQQILLFRELGF
CCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCH
SLREIAAILESPGFDRRQALLAHREALLQRKARIERLIATVDRTLAAMEREDAPMDTREE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
MKELFDGFDPGEYEEEARQRWGGSREFRESAERTRKYTRQDWQRIAAEDGEIYGNIARLM
HHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DRDPADPAVQEWVGRWHEHISKWYYDCSLEVFRGLGEMYVQDERFTRNIDMTKPGLARFL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RDAMQIYCDRREGK
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]