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The map label for this gene is yfhA [H]

Identifier: 51892422

GI number: 51892422

Start: 1422932

End: 1423963

Strand: Reverse

Name: yfhA [H]

Synonym: STH1284

Alternate gene names: 51892422

Gene position: 1423963-1422932 (Counterclockwise)

Preceding gene: 51892423

Following gene: 51892421

Centisome position: 39.93

GC content: 73.35

Gene sequence:

>1032_bases
ATGAGCGCCCGTCGCCTTCGCCTCGTACAGGCCGGCCCCTTCGCCTTCCGGGTCGATCCGGGGATGGTCGCCCGCGTGGC
CGGGGCCTGGCTGGCGCTGCTGGCCCTGGGCGCCTGGGGCCTCACCCTGGGCAGCTACCGCCTCCCCGTGATCGATGTGG
TCCGTTCGCTGCTGGGCGCCGGAACCGCCGATACCCAGTTCATCGTGATGACCCTCCGGCTCCCCCGGGTACTGGCCGCC
ATGCTGGTGGGGCCCGCCCTGGCCATGTCCGGTGCGATCTTCCAGGGCCTCCTCCGCAACCCGCTGGTCTCGCCGGACGT
GATCGGCGTCAACGCAGGAGCCTCGGTGGCAGCCGTTTACTGGATCGTGACCCACCGCCCCCCCGCCCTCTTGCCCCTGA
TCGCCTTCGCTGGGGCGCTGGCCGCCGCGGCCTTCGTCTACCTGCTCACCTGGCGCGGCCACATCTCGGGGGCCCGGCTG
ATCCTGGTGGGCATCGGCGCCAACGCCCTGCTGACGGCGGCCACCACGGCGATCTTCCTGCGGGCGGACGTCTACGAGGC
GGCCTCGGCCTACCGGTGGATGACCGGCAGCCTGGCCGGCAGCGACTGGTCGGACGTGATCACCCTGGCCGTGGCCCTTG
CGGTGCTGGTTCCCCCGGGGCTCGTGCTGATGTGGCCCCTGCGGGCGCTGCAGTACGGCGACCTGACGGCCCGGAGCCTG
GGGCTGCCCGTGGAGGGGGTGCGCCTGGCCCTGATGGCGGTGGGATGCGGCCTGAGCGCCGCCGCCGTGTCGGTGGCGGG
GCCGGTGGGCTTCGTGGCCTTCATGGTGCCCCACCTGGCCCGCATGCTGGCGGGACCGCCGGGCGGCGGCCTGTTCCTGT
TCACCGGCGCCCTGGGCGGCCTGCTGCTCTTGGGCGCGGACCTGGTGGGGCAGCACGCGCTGCCGGTGAGCCTGCCGGTG
GGCGTCATCACCGCCGCGCTGGGCGCCCCGTACTTCCTGTTCCTCCTCTATCGCACCAACGCACGGATGTAG

Upstream 100 bases:

>100_bases
TGATGATGCGTCCGGCGGAGGTACAGGTCGGCGTCGTGACGGCCTTGGTAGGCGCCCCTTTCCTGATCTACTTGGCGCGG
CGCCGGCAGGTGGCGGAGCC

Downstream 100 bases:

>100_bases
GTGACCGGATATGAGCCGTCTGACCGCCGAACAGGTGACCCTCGCCTACGGATCCCACCCCGTGATCACCGGCCTGAGCC
TGTGCATCCCGGACGGCGCC

Product: iron ABC transporter permease protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSARRLRLVQAGPFAFRVDPGMVARVAGAWLALLALGAWGLTLGSYRLPVIDVVRSLLGAGTADTQFIVMTLRLPRVLAA
MLVGPALAMSGAIFQGLLRNPLVSPDVIGVNAGASVAAVYWIVTHRPPALLPLIAFAGALAAAAFVYLLTWRGHISGARL
ILVGIGANALLTAATTAIFLRADVYEAASAYRWMTGSLAGSDWSDVITLAVALAVLVPPGLVLMWPLRALQYGDLTARSL
GLPVEGVRLALMAVGCGLSAAAVSVAGPVGFVAFMVPHLARMLAGPPGGGLFLFTGALGGLLLLGADLVGQHALPVSLPV
GVITAALGAPYFLFLLYRTNARM

Sequences:

>Translated_343_residues
MSARRLRLVQAGPFAFRVDPGMVARVAGAWLALLALGAWGLTLGSYRLPVIDVVRSLLGAGTADTQFIVMTLRLPRVLAA
MLVGPALAMSGAIFQGLLRNPLVSPDVIGVNAGASVAAVYWIVTHRPPALLPLIAFAGALAAAAFVYLLTWRGHISGARL
ILVGIGANALLTAATTAIFLRADVYEAASAYRWMTGSLAGSDWSDVITLAVALAVLVPPGLVLMWPLRALQYGDLTARSL
GLPVEGVRLALMAVGCGLSAAAVSVAGPVGFVAFMVPHLARMLAGPPGGGLFLFTGALGGLLLLGADLVGQHALPVSLPV
GVITAALGAPYFLFLLYRTNARM
>Mature_342_residues
SARRLRLVQAGPFAFRVDPGMVARVAGAWLALLALGAWGLTLGSYRLPVIDVVRSLLGAGTADTQFIVMTLRLPRVLAAM
LVGPALAMSGAIFQGLLRNPLVSPDVIGVNAGASVAAVYWIVTHRPPALLPLIAFAGALAAAAFVYLLTWRGHISGARLI
LVGIGANALLTAATTAIFLRADVYEAASAYRWMTGSLAGSDWSDVITLAVALAVLVPPGLVLMWPLRALQYGDLTARSLG
LPVEGVRLALMAVGCGLSAAAVSVAGPVGFVAFMVPHLARMLAGPPGGGLFLFTGALGGLLLLGADLVGQHALPVSLPVG
VITAALGAPYFLFLLYRTNARM

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=307, Percent_Identity=38.7622149837134, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=36.4285714285714, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788004, Length=288, Percent_Identity=35.7638888888889, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790741, Length=294, Percent_Identity=34.0136054421769, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=35.9223300970874, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=31.8021201413428, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35375; Mature: 35244

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARRLRLVQAGPFAFRVDPGMVARVAGAWLALLALGAWGLTLGSYRLPVIDVVRSLLGA
CCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
GTADTQFIVMTLRLPRVLAAMLVGPALAMSGAIFQGLLRNPLVSPDVIGVNAGASVAAVY
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEE
WIVTHRPPALLPLIAFAGALAAAAFVYLLTWRGHISGARLILVGIGANALLTAATTAIFL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHH
RADVYEAASAYRWMTGSLAGSDWSDVITLAVALAVLVPPGLVLMWPLRALQYGDLTARSL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHC
GLPVEGVRLALMAVGCGLSAAAVSVAGPVGFVAFMVPHLARMLAGPPGGGLFLFTGALGG
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHH
LLLLGADLVGQHALPVSLPVGVITAALGAPYFLFLLYRTNARM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SARRLRLVQAGPFAFRVDPGMVARVAGAWLALLALGAWGLTLGSYRLPVIDVVRSLLGA
CCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
GTADTQFIVMTLRLPRVLAAMLVGPALAMSGAIFQGLLRNPLVSPDVIGVNAGASVAAVY
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEE
WIVTHRPPALLPLIAFAGALAAAAFVYLLTWRGHISGARLILVGIGANALLTAATTAIFL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHH
RADVYEAASAYRWMTGSLAGSDWSDVITLAVALAVLVPPGLVLMWPLRALQYGDLTARSL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHC
GLPVEGVRLALMAVGCGLSAAAVSVAGPVGFVAFMVPHLARMLAGPPGGGLFLFTGALGG
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHH
LLLLGADLVGQHALPVSLPVGVITAALGAPYFLFLLYRTNARM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]