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The map label for this gene is mtnA1 [H]

Identifier: 51891954

GI number: 51891954

Start: 915862

End: 916911

Strand: Reverse

Name: mtnA1 [H]

Synonym: STH816

Alternate gene names: 51891954

Gene position: 916911-915862 (Counterclockwise)

Preceding gene: 51891965

Following gene: 51891953

Centisome position: 25.71

GC content: 71.9

Gene sequence:

>1050_bases
GTGAACGGACCGAAGCTGCCGCTGCTGACCAACCGGGCCGACACGCTGAAGTACGAGGACGGGGTGGTGCGGATCCTCGA
CCGGCGCCGGCTGCCGGAGGAGACCGTCTTCGTGGACTGCCGGGACTACCGGGAGGTGGCCCGGGCCATCGTGGACATGG
TGATCCAGGGGGCGCCGCCCCTCGCCTACGCCGCCGGTTACGGCCTGGCCCTGGCCTGCCGCCAGAGCCGGGATCTCCCC
GCGCCGGAGCGCCGCCGGGCCCTGGAGCAGGCCCACCGGGAGCTGCGGGCCACCCGGCCCACGGGGGCCGACATCTTCCC
GCTGCTGGACCGGGCCCTGGCCCTGGCGCTGGCCGCCCTCGAAGAGGGGCGCGACCCGGAGGCGGCGGTGAGGGAGTTCG
TGGACGGGCAGATCCGGGCCGGCGACCGGGCCGCCCGGCTGTGCGGTTCCCACGCCGCCGGCCTGCTGGAGGACGGCGAC
CGGATCCTCACCCACTGCTTCGCAGGCGCCGCCCTGAACTACATGCTCTACTTCGCCCTGAAGGCGGGGAAGCGGATCGA
GCTTATCGCCACCGAGACCCGGCCTTACCTGCAGGGAGCCAGGCTCACCGCCGCCCAGGCCCGGGAGATCGGCGTGCCGG
TGACCCTGGTGACCGACAACATGCCGGGATACCTGTTCTACCGGGGGATGATCACCAAGTACGTGACCGCGGCCGACTCG
ATCTCCCTGGACGGGCACGTCTCCAACAAGATCGGCACCTTCCAGTACGCGGTGCTGGCGCACCACTTCGGCGTGCCCTT
CATGGTGCTGGGCTACGATGGCCCCGACCGCGAGCGGGCCACCGCGGCGGACATCCCCATCGAGGAGCGGGACCCGGAGG
AGGTCTTCTACTGCCGCGGCGTGCGCACCGCCGCGGAGGGGATCCGGGGGTACTACCCGGCCTTTGACATCACGCCGCCG
CAGTACGTGAGCGTGATCGCCACGGACCGGGGGCTGTTCTCCCCCTGGAACGTGCGGGACTACTTCAGGGCCCCGGAGCC
GGAGGAGTAG

Upstream 100 bases:

>100_bases
CGTGGAGGGGCAATGTCCGTTTTGTGACACTTATCGACCGGACCGGCGCCCAGCGCTGCGGCATGATGGGAAGGAGACAG
AACCCAGGGGAGGAAAGGCC

Downstream 100 bases:

>100_bases
CATGGTCGATACGGTCATCATCGGGGGTACGGCGGCGTACCACCTGCAGTTCGACCCGGGCTGGACGGAGCGGACCGTGG
AGACCCCCTTCGGCCCGGCC

Product: translation initiation factor eIF-2B alpha subunit

Products: NA

Alternate protein names: M1Pi 1; MTR-1-P isomerase 1; S-methyl-5-thioribose-1-phosphate isomerase 1 [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNGPKLPLLTNRADTLKYEDGVVRILDRRRLPEETVFVDCRDYREVARAIVDMVIQGAPPLAYAAGYGLALACRQSRDLP
APERRRALEQAHRELRATRPTGADIFPLLDRALALALAALEEGRDPEAAVREFVDGQIRAGDRAARLCGSHAAGLLEDGD
RILTHCFAGAALNYMLYFALKAGKRIELIATETRPYLQGARLTAAQAREIGVPVTLVTDNMPGYLFYRGMITKYVTAADS
ISLDGHVSNKIGTFQYAVLAHHFGVPFMVLGYDGPDRERATAADIPIEERDPEEVFYCRGVRTAAEGIRGYYPAFDITPP
QYVSVIATDRGLFSPWNVRDYFRAPEPEE

Sequences:

>Translated_349_residues
MNGPKLPLLTNRADTLKYEDGVVRILDRRRLPEETVFVDCRDYREVARAIVDMVIQGAPPLAYAAGYGLALACRQSRDLP
APERRRALEQAHRELRATRPTGADIFPLLDRALALALAALEEGRDPEAAVREFVDGQIRAGDRAARLCGSHAAGLLEDGD
RILTHCFAGAALNYMLYFALKAGKRIELIATETRPYLQGARLTAAQAREIGVPVTLVTDNMPGYLFYRGMITKYVTAADS
ISLDGHVSNKIGTFQYAVLAHHFGVPFMVLGYDGPDRERATAADIPIEERDPEEVFYCRGVRTAAEGIRGYYPAFDITPP
QYVSVIATDRGLFSPWNVRDYFRAPEPEE
>Mature_349_residues
MNGPKLPLLTNRADTLKYEDGVVRILDRRRLPEETVFVDCRDYREVARAIVDMVIQGAPPLAYAAGYGLALACRQSRDLP
APERRRALEQAHRELRATRPTGADIFPLLDRALALALAALEEGRDPEAAVREFVDGQIRAGDRAARLCGSHAAGLLEDGD
RILTHCFAGAALNYMLYFALKAGKRIELIATETRPYLQGARLTAAQAREIGVPVTLVTDNMPGYLFYRGMITKYVTAADS
ISLDGHVSNKIGTFQYAVLAHHFGVPFMVLGYDGPDRERATAADIPIEERDPEEVFYCRGVRTAAEGIRGYYPAFDITPP
QYVSVIATDRGLFSPWNVRDYFRAPEPEE

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=348, Percent_Identity=32.4712643678161, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI23943880, Length=330, Percent_Identity=30.6060606060606, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI4503503, Length=203, Percent_Identity=28.0788177339901, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17557462, Length=343, Percent_Identity=27.4052478134111, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17557123, Length=274, Percent_Identity=26.2773722627737, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325375, Length=389, Percent_Identity=25.4498714652956, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322878, Length=265, Percent_Identity=23.3962264150943, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357667, Length=353, Percent_Identity=31.728045325779, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24651647, Length=353, Percent_Identity=31.728045325779, Blast_Score=138, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38704; Mature: 38704

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPKLPLLTNRADTLKYEDGVVRILDRRRLPEETVFVDCRDYREVARAIVDMVIQGAPP
CCCCCCCEECCCCCCEEECCCHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCC
LAYAAGYGLALACRQSRDLPAPERRRALEQAHRELRATRPTGADIFPLLDRALALALAAL
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EEGRDPEAAVREFVDGQIRAGDRAARLCGSHAAGLLEDGDRILTHCFAGAALNYMLYFAL
HCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
KAGKRIELIATETRPYLQGARLTAAQAREIGVPVTLVTDNMPGYLFYRGMITKYVTAADS
HCCCEEEEEEECCCCHHCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
ISLDGHVSNKIGTFQYAVLAHHFGVPFMVLGYDGPDRERATAADIPIEERDPEEVFYCRG
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHEEEECC
VRTAAEGIRGYYPAFDITPPQYVSVIATDRGLFSPWNVRDYFRAPEPEE
HHHHHHHHHCCCCCCCCCCHHHEEEEEECCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MNGPKLPLLTNRADTLKYEDGVVRILDRRRLPEETVFVDCRDYREVARAIVDMVIQGAPP
CCCCCCCEECCCCCCEEECCCHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCC
LAYAAGYGLALACRQSRDLPAPERRRALEQAHRELRATRPTGADIFPLLDRALALALAAL
HHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
EEGRDPEAAVREFVDGQIRAGDRAARLCGSHAAGLLEDGDRILTHCFAGAALNYMLYFAL
HCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
KAGKRIELIATETRPYLQGARLTAAQAREIGVPVTLVTDNMPGYLFYRGMITKYVTAADS
HCCCEEEEEEECCCCHHCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
ISLDGHVSNKIGTFQYAVLAHHFGVPFMVLGYDGPDRERATAADIPIEERDPEEVFYCRG
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHEEEECC
VRTAAEGIRGYYPAFDITPPQYVSVIATDRGLFSPWNVRDYFRAPEPEE
HHHHHHHHHCCCCCCCCCCHHHEEEEEECCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA