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The map label for this gene is livM [H]

Identifier: 51891939

GI number: 51891939

Start: 897833

End: 898858

Strand: Reverse

Name: livM [H]

Synonym: STH801

Alternate gene names: 51891939

Gene position: 898858-897833 (Counterclockwise)

Preceding gene: 51891940

Following gene: 51891938

Centisome position: 25.21

GC content: 68.62

Gene sequence:

>1026_bases
ATGGGCAAGAAGCTGCTCTTCCTCCTGGGCGCCCTGGCCGTGCTGGCGCTGCCCTACGCGCTGCCTGACGAATGGTCGTG
GCTGGTGCTGCTCACCAACCGGGCCCTGATCCTGGCCATCGCGGCCATCGGCCTCAACCTGCTCACCGGCTTCGCCGGCC
AGATCTCCATCGGCCACGCGGCCTTCATGGCCATCGGCGCCTTCGCCAGCTACGGCCTCACCGCCAAGGTCGGCATTCCC
TTCTGGGGCGCCCTGCCGCTGGCAGGGCTGATCAGCGCCGCCGTGGGCTACGCCCTGGGCTTCCCGGCGCTCCGGCTGCA
GGGCCACTACCTGGCCATCGCCACCCTGGGCTTCGGCGTGGCGGTGCCCCAGATCCTCAACCTCTGGAAGGGGCTCTCCG
GCGGCTGGACCGGGGTGAAGCCCGCCGCCCCTTACCTCTATGGCCTCTACTTCAAGGAGGACCGCCCCTACTACTACCTG
ATCCTGATCGCCCTGGCCCTCCTCACCTGGGTGGCCCTGAACATCGCCAGACGGCGCACCGGTCGGGCCTTCATCGCCCT
GCGGGACAGCAGCGTCGCCGCGCAGGCGATGGGCATCAGCCTGGCCCGGTACAAGACCACCGCCTTCGCCCTCTCGGCGT
TCTACGCCGGCATCGCCGGCAGCCTCTGGGCCCACATGATGAACTACATCGCCCCCCACGACTTCAACCTGGCCCTGTCG
ATGGAGCTGTTCACCATCATCGTGCTGGGCGGCCTGGCCTCGGTGCCCGGCTCGATCGTGGGTTCGCTGTTCATGTCCCT
GATGCCCAAGGCCGTGGAACGGATCTCGCTGGCGCTTCAGCGGTCGGGGGCCTTCGACCATTCCCCGTTCCTCATGAACG
TCTTCAAGAACCTGAATCAGGTGCTGACGGGCGTCATCCTGGTGCTGGTGGTGCTCTACCTGCCCCTGGGGCTCGTGGAC
CTGTGGCGGAGGCTGCAGCACTGGTGGGCCGGGCGCCGGCACGCCGCGGCCGGGGGGGTGGAGTAG

Upstream 100 bases:

>100_bases
GCAGCTGAAAACCCCCTTTGCCTTCGGCCTCATCGTGCTGGTGCTGATGCTGAGGCCCAGCGGCCTGATGGGGACCGTCC
AGCGAAAGAAGGTGTAGCCC

Downstream 100 bases:

>100_bases
ATGGCCCTGCTGGAGCTCAGGCAGGTGACGATGCGCTTCGGCGGCATCGTCGCGGTGGACCGGCTGGACCTCGCGGTGGA
GGAAGGGACCATCCACGGGC

Product: branched-chain amino acid ABC transporter permease protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGKKLLFLLGALAVLALPYALPDEWSWLVLLTNRALILAIAAIGLNLLTGFAGQISIGHAAFMAIGAFASYGLTAKVGIP
FWGALPLAGLISAAVGYALGFPALRLQGHYLAIATLGFGVAVPQILNLWKGLSGGWTGVKPAAPYLYGLYFKEDRPYYYL
ILIALALLTWVALNIARRRTGRAFIALRDSSVAAQAMGISLARYKTTAFALSAFYAGIAGSLWAHMMNYIAPHDFNLALS
MELFTIIVLGGLASVPGSIVGSLFMSLMPKAVERISLALQRSGAFDHSPFLMNVFKNLNQVLTGVILVLVVLYLPLGLVD
LWRRLQHWWAGRRHAAAGGVE

Sequences:

>Translated_341_residues
MGKKLLFLLGALAVLALPYALPDEWSWLVLLTNRALILAIAAIGLNLLTGFAGQISIGHAAFMAIGAFASYGLTAKVGIP
FWGALPLAGLISAAVGYALGFPALRLQGHYLAIATLGFGVAVPQILNLWKGLSGGWTGVKPAAPYLYGLYFKEDRPYYYL
ILIALALLTWVALNIARRRTGRAFIALRDSSVAAQAMGISLARYKTTAFALSAFYAGIAGSLWAHMMNYIAPHDFNLALS
MELFTIIVLGGLASVPGSIVGSLFMSLMPKAVERISLALQRSGAFDHSPFLMNVFKNLNQVLTGVILVLVVLYLPLGLVD
LWRRLQHWWAGRRHAAAGGVE
>Mature_340_residues
GKKLLFLLGALAVLALPYALPDEWSWLVLLTNRALILAIAAIGLNLLTGFAGQISIGHAAFMAIGAFASYGLTAKVGIPF
WGALPLAGLISAAVGYALGFPALRLQGHYLAIATLGFGVAVPQILNLWKGLSGGWTGVKPAAPYLYGLYFKEDRPYYYLI
LIALALLTWVALNIARRRTGRAFIALRDSSVAAQAMGISLARYKTTAFALSAFYAGIAGSLWAHMMNYIAPHDFNLALSM
ELFTIIVLGGLASVPGSIVGSLFMSLMPKAVERISLALQRSGAFDHSPFLMNVFKNLNQVLTGVILVLVVLYLPLGLVDL
WRRLQHWWAGRRHAAAGGVE

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=313, Percent_Identity=32.5878594249201, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 36657; Mature: 36526

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKLLFLLGALAVLALPYALPDEWSWLVLLTNRALILAIAAIGLNLLTGFAGQISIGHA
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEHHHH
AFMAIGAFASYGLTAKVGIPFWGALPLAGLISAAVGYALGFPALRLQGHYLAIATLGFGV
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHEECCCEEEEEHHHHHH
AVPQILNLWKGLSGGWTGVKPAAPYLYGLYFKEDRPYYYLILIALALLTWVALNIARRRT
HHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
GRAFIALRDSSVAAQAMGISLARYKTTAFALSAFYAGIAGSLWAHMMNYIAPHDFNLALS
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
MELFTIIVLGGLASVPGSIVGSLFMSLMPKAVERISLALQRSGAFDHSPFLMNVFKNLNQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VLTGVILVLVVLYLPLGLVDLWRRLQHWWAGRRHAAAGGVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GKKLLFLLGALAVLALPYALPDEWSWLVLLTNRALILAIAAIGLNLLTGFAGQISIGHA
CCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEHHHH
AFMAIGAFASYGLTAKVGIPFWGALPLAGLISAAVGYALGFPALRLQGHYLAIATLGFGV
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHEECCCEEEEEHHHHHH
AVPQILNLWKGLSGGWTGVKPAAPYLYGLYFKEDRPYYYLILIALALLTWVALNIARRRT
HHHHHHHHHCCCCCCCCCCCCCCHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
GRAFIALRDSSVAAQAMGISLARYKTTAFALSAFYAGIAGSLWAHMMNYIAPHDFNLALS
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
MELFTIIVLGGLASVPGSIVGSLFMSLMPKAVERISLALQRSGAFDHSPFLMNVFKNLNQ
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VLTGVILVLVVLYLPLGLVDLWRRLQHWWAGRRHAAAGGVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]