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The map label for this gene is pepQ [H]

Identifier: 51891913

GI number: 51891913

Start: 872117

End: 873298

Strand: Reverse

Name: pepQ [H]

Synonym: STH775

Alternate gene names: 51891913

Gene position: 873298-872117 (Counterclockwise)

Preceding gene: 51891921

Following gene: 51891907

Centisome position: 24.49

GC content: 73.52

Gene sequence:

>1182_bases
ATGCTGCTGACGCCCCGCCACGAGCTGGACCTCCGCATCGGCCGGCTGCAGGCGGCCCTGCGCGACCTGGGGCTGGACGG
CGCCCTGCTCCACAGCACCACGTCGCTGCTGTACTTCACGGGGTCCGCCCAGCAGGGGCATCTCTGGGTGCCGGCGAACG
GAGAGCCCCGGTACCTGGTGCGCCGGGTGCTGGAGCGCGCCCGCCGCGAGTGCGCGCTGCCCGGCATCGAGCCGCTCACC
ACCCTGCGCGCGCTGCCGGACCACCTGGGCGGGGCCCGCCGGATCGGGATGGAGCTGGACCGGCTGCCGGTGGCGCAGTT
CGAGGTCTACCGGCGGCATCTGCCCGGCGTGGATGCGGCCGACGTGGGTCCTGTCCTGCGCCGGCTCCGCTCCGTCAAGT
CGCCGTGGGAGGTGGAACGCATCCGGGCTGCGGCCAGGGCGGCCGACGAGACCTACCGGGCGCTGTTTGCCGCGCTGCGG
GAGGGAATGACCGAGCTGGAGCTGTCGGTGGTGGGCGAGGGCGCCCAGCGGCTGGCCGGCGCGCAGGGCATGATCCGCTG
GCACGCGCACAACGCCTTCGAGTCCCCGGCCATGATGGTACTGGCCGGGGAGACGGCGCTGGCGTTCTCCTTCGCCGACA
CCCCCTTCGGCGGGGAGGGGCTCACCCCGGCCGCCCCGTACGGCGCGAGCCGGCGCCCGATCCGCCGGGACGAGCCCGTC
TGCGTCGACTTCCCGACGGTGGTGGATGGCTACGTCCACGACCAGACCCGCACCATGGTGATCGGAAAGCTACCCCGGCA
GCTCGTGGAGGCCCACGACACCGCCCGGCAGATCCTGGACATGGTCGCCCGGGAGGCGCGCCCCGGCGCCACCGGCCAGC
AGCTCTGGGAGCGAAGCGTGGACATCGCGCGCAGGGCGGGCCTGGAGGAGCACTTCATGGGGGCGGGCAACAGCCGGGTA
CGGTTCGTCGGCCACGGCGTGGGGCTCGAGCTGGACGAATGGCCGATCCTGGCTCCGAAGCAGACCACCCCGCTGGAGGC
CGGCAACGTGATCGCGGTGGAGCCCAAGTTCTTCTTCCCCGGCGTGGGCGCGGTGGGGCTGGAGTCCACCTTCCTGGTGA
CCCCGGACGGGGCGGAGCGGCTCTCGATCACGCCGGAGGAGCTCGGCGTCAAGGACGCGTAG

Upstream 100 bases:

>100_bases
CTGCGTCTGGTCCAGCGTATGCAGCGGGGCCCCCCGTCGCCCCAGGGCGGCGGCCGTCGTCATAATGGATCAGAAACCCT
GGTAAAGGAGAGGAATTCCC

Downstream 100 bases:

>100_bases
GGCGGGCCCCCGCATGACGGGGCCCGCCCCGAGCCGGCCGGTGGCCAGGTGGAGCACCCGGTGCCGGAGCTTGCCCTGGC
CCGTATCCTCCTCAACGTAG

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLLTPRHELDLRIGRLQAALRDLGLDGALLHSTTSLLYFTGSAQQGHLWVPANGEPRYLVRRVLERARRECALPGIEPLT
TLRALPDHLGGARRIGMELDRLPVAQFEVYRRHLPGVDAADVGPVLRRLRSVKSPWEVERIRAAARAADETYRALFAALR
EGMTELELSVVGEGAQRLAGAQGMIRWHAHNAFESPAMMVLAGETALAFSFADTPFGGEGLTPAAPYGASRRPIRRDEPV
CVDFPTVVDGYVHDQTRTMVIGKLPRQLVEAHDTARQILDMVAREARPGATGQQLWERSVDIARRAGLEEHFMGAGNSRV
RFVGHGVGLELDEWPILAPKQTTPLEAGNVIAVEPKFFFPGVGAVGLESTFLVTPDGAERLSITPEELGVKDA

Sequences:

>Translated_393_residues
MLLTPRHELDLRIGRLQAALRDLGLDGALLHSTTSLLYFTGSAQQGHLWVPANGEPRYLVRRVLERARRECALPGIEPLT
TLRALPDHLGGARRIGMELDRLPVAQFEVYRRHLPGVDAADVGPVLRRLRSVKSPWEVERIRAAARAADETYRALFAALR
EGMTELELSVVGEGAQRLAGAQGMIRWHAHNAFESPAMMVLAGETALAFSFADTPFGGEGLTPAAPYGASRRPIRRDEPV
CVDFPTVVDGYVHDQTRTMVIGKLPRQLVEAHDTARQILDMVAREARPGATGQQLWERSVDIARRAGLEEHFMGAGNSRV
RFVGHGVGLELDEWPILAPKQTTPLEAGNVIAVEPKFFFPGVGAVGLESTFLVTPDGAERLSITPEELGVKDA
>Mature_393_residues
MLLTPRHELDLRIGRLQAALRDLGLDGALLHSTTSLLYFTGSAQQGHLWVPANGEPRYLVRRVLERARRECALPGIEPLT
TLRALPDHLGGARRIGMELDRLPVAQFEVYRRHLPGVDAADVGPVLRRLRSVKSPWEVERIRAAARAADETYRALFAALR
EGMTELELSVVGEGAQRLAGAQGMIRWHAHNAFESPAMMVLAGETALAFSFADTPFGGEGLTPAAPYGASRRPIRRDEPV
CVDFPTVVDGYVHDQTRTMVIGKLPRQLVEAHDTARQILDMVAREARPGATGQQLWERSVDIARRAGLEEHFMGAGNSRV
RFVGHGVGLELDEWPILAPKQTTPLEAGNVIAVEPKFFFPGVGAVGLESTFLVTPDGAERLSITPEELGVKDA

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=264, Percent_Identity=29.9242424242424, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 43038; Mature: 43038

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTPRHELDLRIGRLQAALRDLGLDGALLHSTTSLLYFTGSAQQGHLWVPANGEPRYLV
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCEEEEECCCCHHHHH
RRVLERARRECALPGIEPLTTLRALPDHLGGARRIGMELDRLPVAQFEVYRRHLPGVDAA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHCCHHHCCCHHHHHHHHHHCCCCCCH
DVGPVLRRLRSVKSPWEVERIRAAARAADETYRALFAALREGMTELELSVVGEGAQRLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHC
AQGMIRWHAHNAFESPAMMVLAGETALAFSFADTPFGGEGLTPAAPYGASRRPIRRDEPV
CCCEEEEECCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCE
CVDFPTVVDGYVHDQTRTMVIGKLPRQLVEAHDTARQILDMVAREARPGATGQQLWERSV
EEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DIARRAGLEEHFMGAGNSRVRFVGHGVGLELDEWPILAPKQTTPLEAGNVIAVEPKFFFP
HHHHHCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEECC
GVGAVGLESTFLVTPDGAERLSITPEELGVKDA
CCCCCCCCCEEEECCCCCCEEECCHHHCCCCCC
>Mature Secondary Structure
MLLTPRHELDLRIGRLQAALRDLGLDGALLHSTTSLLYFTGSAQQGHLWVPANGEPRYLV
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCCCCEEEEECCCCHHHHH
RRVLERARRECALPGIEPLTTLRALPDHLGGARRIGMELDRLPVAQFEVYRRHLPGVDAA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHCCHHHCCCHHHHHHHHHHCCCCCCH
DVGPVLRRLRSVKSPWEVERIRAAARAADETYRALFAALREGMTELELSVVGEGAQRLAG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHC
AQGMIRWHAHNAFESPAMMVLAGETALAFSFADTPFGGEGLTPAAPYGASRRPIRRDEPV
CCCEEEEECCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCE
CVDFPTVVDGYVHDQTRTMVIGKLPRQLVEAHDTARQILDMVAREARPGATGQQLWERSV
EEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DIARRAGLEEHFMGAGNSRVRFVGHGVGLELDEWPILAPKQTTPLEAGNVIAVEPKFFFP
HHHHHCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEECC
GVGAVGLESTFLVTPDGAERLSITPEELGVKDA
CCCCCCCCCEEEECCCCCCEEECCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]