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The map label for this gene is luxS [H]

Identifier: 51598633

GI number: 51598633

Start: 386094

End: 386567

Strand: Direct

Name: luxS [H]

Synonym: BG0376

Alternate gene names: 51598633

Gene position: 386094-386567 (Clockwise)

Preceding gene: 51598632

Following gene: 51598656

Centisome position: 42.7

GC content: 30.38

Gene sequence:

>474_bases
ATGAAAAAAATAACAAGCTTTACAATAGATCATACAAAATTAAACCCCGGCATATATGTCTCAAGAAAAGACACCTTTGA
AAATGTAATATTTACTACAATAGACATTAGAATCAAAGCTCCCAACATTGAACCAATAATTGAAAACGCAGCAATACATA
CAATAGAGCATATAGGAGCTACTTTACTTAGAAATAATGAAGTTTGGACCGAAAAAATAGTATATTTTGGTCCCATGGGG
TGCAGAACTGGTTTTTATTTAATAATTTTTGGAAACTATGAAAGCAAAGATCTTATTGACTTAATATCATGGCTTTTTTC
CGAAATTGTGAACTTTTCAGAGCCCATTCCAGGCGCAAGCCATAAAGAATGCGGGAATTACAAAGATCATAACCTTGATA
TGGCTAAATATGAATCTTCTAAATACTTACAAATATTAAACAATATTAAAGAAGAAAATTTAAAATATCCCTAG

Upstream 100 bases:

>100_bases
CCATATATCTTAAAACTTGTACGTATGGTCAGTTGGGAAAGAATGAATTTGAATGGGAAAAATTAGATTTTGTAAAAAAA
ATACAAACGGTGCTAAAAAA

Downstream 100 bases:

>100_bases
TTCATAAAATTTACAAAATAGAAAGTATCTCGCTGTCATTTTTTGTTGCTACGTCAAGCTGAAAAATAAAGCCTAAAGTT
ATTTTATGCATTTGATTTAA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGATLLRNNEVWTEKIVYFGPMG
CRTGFYLIIFGNYESKDLIDLISWLFSEIVNFSEPIPGASHKECGNYKDHNLDMAKYESSKYLQILNNIKEENLKYP

Sequences:

>Translated_157_residues
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGATLLRNNEVWTEKIVYFGPMG
CRTGFYLIIFGNYESKDLIDLISWLFSEIVNFSEPIPGASHKECGNYKDHNLDMAKYESSKYLQILNNIKEENLKYP
>Mature_157_residues
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGATLLRNNEVWTEKIVYFGPMG
CRTGFYLIIFGNYESKDLIDLISWLFSEIVNFSEPIPGASHKECGNYKDHNLDMAKYESSKYLQILNNIKEENLKYP

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=144, Percent_Identity=31.9444444444444, Blast_Score=75, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18133; Mature: 18133

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGA
CCCCCEEEEECEECCCCEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
TLLRNNEVWTEKIVYFGPMGCRTGFYLIIFGNYESKDLIDLISWLFSEIVNFSEPIPGAS
HHHCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HKECGNYKDHNLDMAKYESSKYLQILNNIKEENLKYP
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKITSFTIDHTKLNPGIYVSRKDTFENVIFTTIDIRIKAPNIEPIIENAAIHTIEHIGA
CCCCCEEEEECEECCCCEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
TLLRNNEVWTEKIVYFGPMGCRTGFYLIIFGNYESKDLIDLISWLFSEIVNFSEPIPGAS
HHHCCCCCCEEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HKECGNYKDHNLDMAKYESSKYLQILNNIKEENLKYP
CCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA