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The map label for this gene is visC

Identifier: 51597493

GI number: 51597493

Start: 3744597

End: 3745817

Strand: Reverse

Name: visC

Synonym: YPTB3183

Alternate gene names: 51597493

Gene position: 3745817-3744597 (Counterclockwise)

Preceding gene: 51597494

Following gene: 51597492

Centisome position: 78.95

GC content: 55.04

Gene sequence:

>1221_bases
ATGCAATCATTTGACATAGTTATCGCCGGTGGTGGGATGGTGGGTCTGGCGCTGGCTTGTGGTTTACAAGGCAGTGGCCT
GCGTATCGCCATTATCGAGCATCAGCCTGCACCGATGCCATTAACGGCACCGTTGACCGGTGAGCTGGCACTGCGAGTCT
CGGCGATCAACGCAGCTAGTGAGCGCTTACTGCAAAAAATCGGGGTGTGGGAAACGATTCAGGCACTGCGTGCTAGCCCG
TACCACGGTATGGAAGTGTGGGATAAAGACAGCTTCGGCAAAATTGCCTTTCATGCGGATGAATATGGCTTCAGCCATCT
TGGCCATATCATTGAAAATCAGGTCATTCAACAAGCATTGTGGCAGCGGGCCAGCCAACTACCAGAGGTGACGGTCTTGG
CACCCGCCAGCTTCAAACAAGTGGCTTGGGGCGAGACGGAAGCGTTTATCACCCTAACCGATGACCGGATGCTCAGTGCT
CGGCTGGTTGTTGGGGCTGATGGCGCACACTCATGGTTACGTCAGCATGCGGATATTCCTCTGACCTTCTGGGATTATGC
CCACCATGCCTTGGTGGCAACTATCCGGACTGACGAGCCGCATCAGGCTACCGCGCGTCAGGTATTCCACGGTGACGGCA
TTTTAGCTTTCCTCCCCTTTAGCGACCCCCACCTCAGTTCTATTGTCTGGTCATTACCGCCTGAGCGTGCCGCCGAGTTA
GCCGTGCTACCCGCCGAGCAATTTAACCGTGAGTTGGCGATGACGTTTGATATGCGCCTTGGGCAATGTCAGCTTGAGAG
TGAGCGGCAAACGTTCCCGCTGACCGGGCGTTATGCCCGTAGCTTTGCCGCGCACCGGCTGGTGTTGGTCGGCGATGCGG
CGCATACCGTGCATCCATTGGCTGGGCAGGGCGTTAATCTGGGCTTTATGGATGTAGCCGAATTAGTGTCTGAACTTCGG
CGTTTACAGCGTCAAGGGAAGGATATTGGTCAGCATCTCTATCTGCGCCGTTATGAACGCCGCCGCAAACACAGTGCTGC
GATGATGCTGGCGAGTATGCAGGGCTTCCGTGATCTGTTTGCTGGCAACAATCCGGCTAAAAAATTATTACGTGATATTG
GGTTAACGCTGGCCGATCACTTGCCGGGGGTTAAACCGCAACTGGTACGGCAGGCGATGGGGCTGAATGATTTGCCAGAA
TGGCTGGAGCGTTCTCAATAA

Upstream 100 bases:

>100_bases
AAATCGTTCCCGACCAATTTGCTTCTCGTTTGCCGCCTCCCTGCATCGAGAAATCTATAGAGTAAATAAAGTTCATATTT
TCATGGGGAAATGTTTCGGC

Downstream 100 bases:

>100_bases
TACGCCGTTACGGGTATTAATGAGACACCGCCAGTGTGTGTCTAAAGCAGCCTTCGGTAGTGCCTCAAGCCGCGTGCGCT
CTGGCGCTGATGGGGCTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPMPLTAPLTGELALRVSAINAASERLLQKIGVWETIQALRASP
YHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQALWQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSA
RLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDEPHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAEL
AVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYARSFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSELR
RLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLFAGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPE
WLERSQ

Sequences:

>Translated_406_residues
MQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPMPLTAPLTGELALRVSAINAASERLLQKIGVWETIQALRASP
YHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQALWQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSA
RLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDEPHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAEL
AVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYARSFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSELR
RLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLFAGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPE
WLERSQ
>Mature_406_residues
MQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPMPLTAPLTGELALRVSAINAASERLLQKIGVWETIQALRASP
YHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQALWQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSA
RLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDEPHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAEL
AVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYARSFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSELR
RLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLFAGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPE
WLERSQ

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=419, Percent_Identity=31.0262529832936, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI32967307, Length=347, Percent_Identity=31.700288184438, Blast_Score=139, Evalue=6e-33,
Organism=Escherichia coli, GI1789273, Length=403, Percent_Identity=71.4640198511166, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1786883, Length=394, Percent_Identity=37.8172588832487, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1789274, Length=397, Percent_Identity=31.9899244332494, Blast_Score=179, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25146631, Length=432, Percent_Identity=30.787037037037, Blast_Score=171, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6321694, Length=458, Percent_Identity=25.9825327510917, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920760, Length=432, Percent_Identity=33.7962962962963, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 45035; Mature: 45035

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPMPLTAPLTGELALRVSAINAAS
CCCEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCEEEEEEHHHHHH
ERLLQKIGVWETIQALRASPYHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQAL
HHHHHHHCHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
WQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSARLVVGADGAHSWLRQHADIP
HHHHHCCCCEEEECCCCHHHHHCCCCCEEEEEECCCEEEEEEEEECCCHHHHHHHCCCCC
LTFWDYAHHALVATIRTDEPHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAEL
EEHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCHHHHHCE
AVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYARSFAAHRLVLVGDAAHTVHPL
EEECHHHHCCEEEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHCEEEEEECCHHHCCCC
AGQGVNLGFMDVAELVSELRRLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPEWLERSQ
CCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPMPLTAPLTGELALRVSAINAAS
CCCEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCEEEEEEHHHHHH
ERLLQKIGVWETIQALRASPYHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQAL
HHHHHHHCHHHHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
WQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSARLVVGADGAHSWLRQHADIP
HHHHHCCCCEEEECCCCHHHHHCCCCCEEEEEECCCEEEEEEEEECCCHHHHHHHCCCCC
LTFWDYAHHALVATIRTDEPHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAEL
EEHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCHHHHHCE
AVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYARSFAAHRLVLVGDAAHTVHPL
EEECHHHHCCEEEEEECCCCCCCEECCCCCCCCCCHHHHHHHHHCEEEEEECCHHHCCCC
AGQGVNLGFMDVAELVSELRRLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPEWLERSQ
CCCCHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]