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The map label for this gene is pdxY

Identifier: 51596606

GI number: 51596606

Start: 2693150

End: 2694010

Strand: Reverse

Name: pdxY

Synonym: YPTB2282

Alternate gene names: 51596606

Gene position: 2694010-2693150 (Counterclockwise)

Preceding gene: 51596607

Following gene: 51596594

Centisome position: 56.78

GC content: 50.29

Gene sequence:

>861_bases
ATGAAAAATATACTTTCTATTCAGTCACACGTCGTTTTTGGCCACGCAGGGAATAGCGCTGCAGAATTTCCTATGCGTCG
TATGGGGGTGAATGTCTGGCCGCTGAATACCGTTCAGTTTTCGAATCATACTCAATATGGTCACTGGACAGGTTGTGTCA
TGCCCGCTAGCCATTTAACTGACATTGTGCAAGGCATTGCCGATATCGATCGACTGAAAGACTGTGATGCGGTTCTGAGT
GGCTATATTGGGTCGCCAGAACAGGGCAGTCATATTCTGGCCGCCGTCGCCCAGGTTAAACAAGCCAATCCAGATGCTTG
GTATTTTTGTGATCCGGTCATGGGGCACCCCGAAAAAGGGTGTATTGTGGCACCGGGGGTGGCCGAATTTTTCTGCAACG
AAGCTTTGCCTGCCAGTGATATGATTGCGCCGAACCTGCTTGAACTTGAGCAACTCAGTGGTGAGCGAGTAGAGAATGTC
GAACAGGCGGTACAGGTTGCCCGTTCTCTTTGCGCTAGGGGGCCAAAAGTCGTGTTAGTCAAGCACCTGAGCCGTGCAGG
CTACCATGCTGACTGCTTCGAAATGTTATTGGTTACCGCAGATGATGCCTGGCATATCAGCCGCCCGCTGGTGGATTTTG
GCAAACGTCAACCGGTTGGTGTCGGTGATTTAACCAGTGGTTTATTGCTGGTGAATTTGTTGAAAGGTGAGCCATTGGAT
AAAGCACTGGAACATGTCACCGCCGCCGTGTATGAAGTGATGCTCAAAACACAGGAAATGGGGGAGTATGAGCTACAGGT
TGTCGCTGCCCAAGAGACTATTGTGACGCCTATCTGCCAGTTTACAGCGGTTAGGCTGTAA

Upstream 100 bases:

>100_bases
CTCTTTTAAGTCAGTGATTCGTGTGAGCGAAAACGGCTAACACCGCTGCAACTTTATGTAAGAAGGGTATACCAAACGCC
CTTAACTTTAGGCCGTACCA

Downstream 100 bases:

>100_bases
TCTAACCATTTTCAATTGCCCCCTAGTGATGGGGGCAATTGATTGATTCTCATTATTTATTACTTGATATCTTCGGCGGC
TAAAGCTGCTTTTACCGCAG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLS
GYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENV
EQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHISRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL

Sequences:

>Translated_286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLS
GYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENV
EQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHISRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
>Mature_286_residues
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLTDIVQGIADIDRLKDCDAVLS
GYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKGCIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENV
EQAVQVARSLCARGPKVVLVKHLSRAGYHADCFEMLLVTADDAWHISRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=180, Percent_Identity=36.1111111111111, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1787924, Length=286, Percent_Identity=75.5244755244755, Blast_Score=446, Evalue=1e-127,
Organism=Escherichia coli, GI1788758, Length=263, Percent_Identity=31.5589353612167, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17507759, Length=268, Percent_Identity=30.9701492537313, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17507757, Length=278, Percent_Identity=30.2158273381295, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324354, Length=275, Percent_Identity=30.1818181818182, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320806, Length=242, Percent_Identity=32.6446280991736, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI45553007, Length=303, Percent_Identity=30.3630363036304, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31169; Mature: 31169

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLT
CCCHHHHHHEEEEECCCCCHHHCCHHHHCCCEECCCEEEECCCCCCCCCCCCCCCHHHHH
DIVQGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
CIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLV
CEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEE
KHLSRAGYHADCFEMLLVTADDAWHISRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
HHHHHCCCCHHHHHHHHHCCCCCHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHH
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNILSIQSHVVFGHAGNSAAEFPMRRMGVNVWPLNTVQFSNHTQYGHWTGCVMPASHLT
CCCHHHHHHEEEEECCCCCHHHCCHHHHCCCEECCCEEEECCCCCCCCCCCCCCCHHHHH
DIVQGIADIDRLKDCDAVLSGYIGSPEQGSHILAAVAQVKQANPDAWYFCDPVMGHPEKG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
CIVAPGVAEFFCNEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLV
CEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEE
KHLSRAGYHADCFEMLLVTADDAWHISRPLVDFGKRQPVGVGDLTSGLLLVNLLKGEPLD
HHHHHCCCCHHHHHHHHHCCCCCHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHH
KALEHVTAAVYEVMLKTQEMGEYELQVVAAQETIVTPICQFTAVRL
HHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA