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The map label for this gene is acoR [H]

Identifier: 51596522

GI number: 51596522

Start: 2585058

End: 2586860

Strand: Reverse

Name: acoR [H]

Synonym: YPTB2196

Alternate gene names: 51596522

Gene position: 2586860-2585058 (Counterclockwise)

Preceding gene: 51596524

Following gene: 51596521

Centisome position: 54.52

GC content: 51.3

Gene sequence:

>1803_bases
ATGCAGGGAAATTTATCAGCCGCCAGCACGCCCACTACGGCGTGCAATCAACGACTCCGTGACTCTTGGCTGCGTAGCCA
ACTCTACGGTTTAGATCGCATGTCCGACGATGTTCCCCGTATTGAGCAGGGAGAACTGGCCGACTTGCTGGTCAGTCACG
CCGTATTACAGCAATTTTCTCAGCCAACAGTGAAAGCGCTGGCTGAGAAAATTGCCGATAAGCAATCGGTAGTGGTCCTC
GCCGATGCCAGTGGATTGGTATTGAATACCTTCGGCGATATACAGGCTCTACAAAAAGCACAACAGTTTGCCCTGACGCC
CGGTAATCTATGGAGTGAATGCAGCCGAGGAACGAATGCCATTGGTACTGCCCTGGCGATTGATGATAGCTGCGAAATCT
ATGGGCATCAGCATTATCTTATTAACAATCAGGGGCTTTACTGCGCGGCTATGCCACTGCAAGCGCCTAACGGACAGATT
GCCGGTGTGCTGGATATATCGGGTCCGGCGTATCACTCCCATCCCCACACACTGGCATGGATAAAAAACGCGGCGAAACA
AATTGAGTATTTATGGGTGAAACAGAGCCTGCATCCAGATCAGTGGCTGATGAGTCTGCATCCACAAATACAAGGCATTG
ATAATATTGAAGAGCTACTACTGGTGTTCTCTGATAACACTCTGATGGCAGCTAACCGTCTGGCGATGCACGAGTTGGCG
TTGGGGGCCGACCAGTTTGGTGCCCTAACCTTCCAGCAACTTTTTCCGCAAAGTAAGCAAGTTGCCAATCAGGTGCCGCA
CCCTTTAATGGCTCGCAATCAACAACGTTATTTCTTTCGCCTACGGGCGCCAGCACGAAGCCACTTCCCTGCAATAATAC
ACGTTCCCACAACATCGGTAACTTCGCCTGACTTATCCTTCTCACTGCGCGATGACGATAAGAAAATGGTGCGATTACTC
AATGCTGGCGTCTCGCTTTGTATAAATGGTGAGACTGGCAGTGGTAAGGAGTATGTTAGCCGGGCTTTACATCAGCAGAG
CCGGTGGCGGCAAGGTAAGTTTGTTGTTATCAACTGCGCTGCCATACCAGAGTCTCTGATTGAATCAGAACTCTTCGGAT
ACCAACCGGGTGCATTTACGGGGGCCAGCAAAAATGGCTATATTGGCAAAATTCGGGAGGCAGACGGTGGCGTACTGTTT
CTGGATGAAATAGGCGATATGCCGTTATCGCTACAAACCCGCTTACTCCGAGTATTGCAAGAAAAAGAGGTGACGCCGCT
GGGTTCTAGCCGTAGTTGGCCAGTCAATTTTGCGGTGGTCTGTGCTACGCATCGGGATCTTCCCCAGTTGGTCGCGGAGG
GTGGGTTCCGTGAAGACCTCCTCTACCGATTGCAAGAGTTCTCTCTAACCATTCCGCCACTGCGTGAATGGCCCGCGCTG
CCCGCCTTTATTTTACAGCTATGGAGGGCGTTGGGCGGTGAGCAACGGGGCATTCGCTTTACGCCAGCACTGCTTGATAC
GCTGGCGAAACATCCCTGGCCGGGTAATGTGCGTCAACTGCAAAGTTTACTGAAGGTATTATTCGCCCTGGCGGATGACG
ATGAGGTTCTTGATTGCGAGACACTGCCTGACAACTTCCGAGGTGAGAATAGTGAACCGTACCCCGCGCTGCAACAGCAT
GACAAGCAGTTTATTGAGAAAACACTGCAATATTTTAACGGTAACATCAGTAAAACTGCCAAGGCTTTGGGCATAGCACG
CAGTACGCTATACCGCCGTGCCGCGCGAGAAAAACGCCAGTAA

Upstream 100 bases:

>100_bases
AAATAGAGAAGGGGTTAATATTTGCGTTGCAAATCGCAACATTAAAATCATTATTGAGACACAATAATGATACATGTGTA
GCGAAGGTGTGAAATTACCA

Downstream 100 bases:

>100_bases
AATAGTATATTCCCTAGCGGCAAGCCGATACCTAAGTGATGGATTCCACTCTGACTCAGAATATGTTAATGATATCAATT
AGATTATTGGTAACAACAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MQGNLSAASTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFSQPTVKALAEKIADKQSVVVL
ADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAMPLQAPNGQI
AGVLDISGPAYHSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAANRLAMHELA
LGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTSVTSPDLSFSLRDDDKKMVRLL
NAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNGYIGKIREADGGVLF
LDEIGDMPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQEFSLTIPPLREWPAL
PAFILQLWRALGGEQRGIRFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCETLPDNFRGENSEPYPALQQH
DKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ

Sequences:

>Translated_600_residues
MQGNLSAASTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFSQPTVKALAEKIADKQSVVVL
ADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAMPLQAPNGQI
AGVLDISGPAYHSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAANRLAMHELA
LGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTSVTSPDLSFSLRDDDKKMVRLL
NAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNGYIGKIREADGGVLF
LDEIGDMPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQEFSLTIPPLREWPAL
PAFILQLWRALGGEQRGIRFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCETLPDNFRGENSEPYPALQQH
DKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ
>Mature_600_residues
MQGNLSAASTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFSQPTVKALAEKIADKQSVVVL
ADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNAIGTALAIDDSCEIYGHQHYLINNQGLYCAAMPLQAPNGQI
AGVLDISGPAYHSHPHTLAWIKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAANRLAMHELA
LGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTSVTSPDLSFSLRDDDKKMVRLL
NAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCAAIPESLIESELFGYQPGAFTGASKNGYIGKIREADGGVLF
LDEIGDMPLSLQTRLLRVLQEKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQEFSLTIPPLREWPAL
PAFILQLWRALGGEQRGIRFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCETLPDNFRGENSEPYPALQQH
DKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=434, Percent_Identity=35.9447004608295, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788905, Length=296, Percent_Identity=40.8783783783784, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87082117, Length=293, Percent_Identity=41.9795221843003, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI1789087, Length=286, Percent_Identity=43.006993006993, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1790437, Length=285, Percent_Identity=40, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1786524, Length=298, Percent_Identity=39.9328859060403, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1788550, Length=412, Percent_Identity=32.7669902912621, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1790299, Length=332, Percent_Identity=36.4457831325301, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI87082152, Length=233, Percent_Identity=41.6309012875536, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI87081872, Length=290, Percent_Identity=36.2068965517241, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI1787583, Length=200, Percent_Identity=38.5, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081858, Length=622, Percent_Identity=25.2411575562701, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789828, Length=154, Percent_Identity=42.8571428571429, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 66788; Mature: 66788

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGNLSAASTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
QPTVKALAEKIADKQSVVVLADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNA
CHHHHHHHHHHCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHCCCCH
IGTALAIDDSCEIYGHQHYLINNQGLYCAAMPLQAPNGQIAGVLDISGPAYHSHPHTLAW
HCEEEEECCCCEEEECEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHH
IKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAANRLAMHELA
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHEEECCCCEEHHHHHHHHHHH
LGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTSV
CCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCC
TSPDLSFSLRDDDKKMVRLLNAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCA
CCCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECH
AIPESLIESELFGYQPGAFTGASKNGYIGKIREADGGVLFLDEIGDMPLSLQTRLLRVLQ
HCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHH
EKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQEFSLTIPPLREWPAL
HCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCC
PAFILQLWRALGGEQRGIRFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCE
HHHHHHHHHHHCCCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECC
TLPDNFRGENSEPYPALQQHDKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQGNLSAASTPTTACNQRLRDSWLRSQLYGLDRMSDDVPRIEQGELADLLVSHAVLQQFS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
QPTVKALAEKIADKQSVVVLADASGLVLNTFGDIQALQKAQQFALTPGNLWSECSRGTNA
CHHHHHHHHHHCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHCCCCCHHHHHHHCCCCH
IGTALAIDDSCEIYGHQHYLINNQGLYCAAMPLQAPNGQIAGVLDISGPAYHSHPHTLAW
HCEEEEECCCCEEEECEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHH
IKNAAKQIEYLWVKQSLHPDQWLMSLHPQIQGIDNIEELLLVFSDNTLMAANRLAMHELA
HHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHEEECCCCEEHHHHHHHHHHH
LGADQFGALTFQQLFPQSKQVANQVPHPLMARNQQRYFFRLRAPARSHFPAIIHVPTTSV
CCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHCCCCEEEEEEECCCCCCCCEEEEECCCCC
TSPDLSFSLRDDDKKMVRLLNAGVSLCINGETGSGKEYVSRALHQQSRWRQGKFVVINCA
CCCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECH
AIPESLIESELFGYQPGAFTGASKNGYIGKIREADGGVLFLDEIGDMPLSLQTRLLRVLQ
HCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHH
EKEVTPLGSSRSWPVNFAVVCATHRDLPQLVAEGGFREDLLYRLQEFSLTIPPLREWPAL
HCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCCC
PAFILQLWRALGGEQRGIRFTPALLDTLAKHPWPGNVRQLQSLLKVLFALADDDEVLDCE
HHHHHHHHHHHCCCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECC
TLPDNFRGENSEPYPALQQHDKQFIEKTLQYFNGNISKTAKALGIARSTLYRRAAREKRQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]